A facile microemulsion template route for producing hollow silica nanospheres as imaging agents and drug nanocarriers

2015 ◽  
Vol 3 (16) ◽  
pp. 3130-3133 ◽  
Author(s):  
Nirun Jatupaiboon ◽  
Yanfang Wang ◽  
Hao Wu ◽  
Xiaojie Song ◽  
Yizhe Song ◽  
...  

Hollow silica nanospheres with uniform size distribution and tuneable shell thickness were synthesized through a one-step reverse microemulsion method at room temperature within 24 h.

2012 ◽  
Vol 622-623 ◽  
pp. 930-938
Author(s):  
Xiao Feng Deng ◽  
Yu Wen ◽  
Liang Wu Lin ◽  
Li Xiong ◽  
Xiong Ying Miao

In this study, Photosan (PS) was loaded onto hollow silica nanospheres using one-step wet chemical-based synthetic route method. Polydispersive index of the Photosan-loaded hollow Silica Nanospheres (PS-loaded NSs) is 0.121±0.01. The photobiological activity of the PS-loaded NSs was evaluated on human cholangiocarcinoma QBC939 cells. Cells were incubated with free PS or PS-loaded NSs for 2 h and then washed with phosphate-buffered saline. Culture medium was added to the wells containing the cells. Finally, the cells were exposed to red light (630 nm) with a light dose of 10J/cm2. The cellular viability was determined after 24 h of incubation. PS-loaded NSs and free PS eliminated about 96.4%±2.0% and 54.7%±1.9% of QBC939 cells, respectively. The phototoxicity was time dependent up to 2 h and concentration dependent at 1-7.5 mg/l. The cells viability decreased with the increase of the light dose in the range of 5-15 J/cm2. In conclusion, PS-loaded NSs are the release systems that promise photodynamic therapy use.


2018 ◽  
Vol 29 (3) ◽  
pp. 1805764 ◽  
Author(s):  
Yanke Wang ◽  
Yan Liu ◽  
Huixia Wu ◽  
Jianping Zhang ◽  
Qiwei Tian ◽  
...  

2020 ◽  
Vol 7 (10) ◽  
pp. 2060-2071 ◽  
Author(s):  
Lei Qiu ◽  
Hang Yang ◽  
Zhigao Dai ◽  
Fengxu Sun ◽  
Jiarui Hao ◽  
...  

A highly stable and efficient CsPbBr3@SiO2 composite phosphor is achieved by protecting the CsPbBr3 QDs from direct exposure to the atmosphere by encapsulating CsPbBr3 into dual-shell hollow silica nanospheres.


Catalysts ◽  
2019 ◽  
Vol 9 (5) ◽  
pp. 481 ◽  
Author(s):  
Xiaoli Zhang ◽  
Juan Wei ◽  
Xiaoming Zhang

Hollow silica nanospheres with ultra-high acid density were fabricated successfully via sulfonation of phenyl-functionalized hollow silica nanospheres, which were synthesized through a single micelle (F127 (EO106PO70EO106))-templated method, with phenyltrimethoxysilane and tetramethoxysilane (TMOS) as silane precursors under neutral conditions. The density of sulfonic acid reached as high as 1.97 mmol/g. The characterization results of 31P-NMR using triethylphosphine oxide as a probe molecule suggested that the acid strength of hybrid solid acids could be systematically tuned by tuning the content of sulfonic acid and higher acid density results in stronger acid strength. Attributed to the unique hollow structure and high-acid density, the sulfonic acid-functionalized hollow silica nanospheres exhibited good catalytic performance in the condensation reaction of benzaldehyde with ethylene glycol. Notably, this study found that the catalytic activity was significantly influenced by the acid density and the ultra-high acid loading was beneficial for the activity due to the enhanced acid strength. This novel solid-acid catalyst also showed good recyclability and could be reused for at least 11 runs.


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