Gold nanorods vs. gold nanoparticles: application in electrochemical sensing of cytosine β-d-arabinoside using metal ion mediated molecularly imprinted polymer

RSC Advances ◽  
2016 ◽  
Vol 6 (84) ◽  
pp. 80679-80691 ◽  
Author(s):  
Bhim Bali Prasad ◽  
Ragini Singh ◽  
Anil Kumar

The determination of an anticancer drug (cytosine arabinoside, Ara-C) in body fluids is very important due to its pharmaceutical and clinical significance.

2014 ◽  
Vol 881-883 ◽  
pp. 93-97 ◽  
Author(s):  
Tian Hua Li ◽  
De Wang ◽  
Hang Zhen Lan ◽  
Ning Gan

An electrochemical sensor for estradiol was prepared by a molecularly imprinted polymer (MIP) film and its recognition properties for estradiol were investigated. The polypyrrole (PPy) film was prepared by electropolymerizing pyrrole on gold nanoparticles (Au NPs) and graphene (Gs) modified glassy carbon (GC) electrode. The electrochemical response of 17β-Estradiol (17β-E2) at the imprinted PPy-Gs-Au/GC electrode was investigated by cyclic voltammetry. The results indicated that the imprinted PPy-Gs-Au/GC electrode can effectively improve the electrochemical signal of 17β-E2 and eliminate interferences of other interfering substances. The results showed that a wide detection linear range (3.0 × 10-9 1.0 × 10-6 mol L-1) for the determination of 17β-E2 with the low detection limit of 1.0 × 10-9 mol L-1 (S/N = 3) was obtained. The proposed sensor exhibited fast balance response time of 10 min, which is propitious to rapid detect 17β-E2 in real samples. The merits of the imprinted electrode suggested an attractive and broadly applicable way for developing the chemical sensor used for the estrogen detection.


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