Metabolic profiling of asthma in mice and the interventional effects of SPA using liquid chromatography and Q-TOF mass spectrometry

2017 ◽  
Vol 13 (6) ◽  
pp. 1172-1181 ◽  
Author(s):  
Li Su ◽  
Lei Shi ◽  
Jian Liu ◽  
Lifei Huang ◽  
Yi Huang ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Lung Disease ◽  
Metabolic Profiling ◽  
Inflammatory Lung Disease

Asthma is a chronic inflammatory lung disease that leads to 250 000 deaths annually.

scholarly journals Metabolic profiling putatively identifies plasma biomarkers of male infertility using UPLC-ESI-IT-TOFMS

RSC Advances ◽  
2018 ◽  
Vol 8 (46) ◽  
pp. 25974-25982 ◽  
Author(s):  
F. J. Zeng ◽  
H. C. Ji ◽  
Z. M. Zhang ◽  
J. K. Luo ◽  
H. M. Lu ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Male Infertility ◽  
Electrospray Ionization ◽  
Metabolic Profiling ◽  
Ion Trap ◽  
Time Of Flight ◽  
Ultra Performance Liquid Chromatography ◽  
Flight Mass Spectrometry ◽  
Potential Biomarkers

Ultra-performance liquid chromatography-electrospray ionization-ion trap-time of flight mass spectrometry combined with chemometrics methods was used to discover potential biomarkers of male infertility based on untargeted plasma metabolomics.

Screening and verification of linearly dependent biomarkers with acute toxicity induced by Aconiti Radix based on liquid chromatography-mass spectrometry-based metabolite profiling

RSC Advances ◽  
2015 ◽  
Vol 5 (126) ◽  
pp. 103915-103924 ◽  
Author(s):  
Yubo Li ◽  
Zhiguo Hou ◽  
Yuming Wang ◽  
Lei Wang ◽  
Liang Ju ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Acute Toxicity ◽  
Linear Dependence ◽  
Metabolic Profiling ◽  
Metabolite Profiling ◽  
Liquid Chromatography Mass Spectrometry ◽  
Toxicity Biomarkers ◽  
Metabolic Profiling Analysis ◽  
Profiling Analysis

We built a method that has three parts: first is to screen the biomarkers with metabolic profiling analysis; second is to determine the linear dependence with acute toxicity biomarkers; third is to validate the biomarkers with different Aconiti Radix involved medicine.

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