scholarly journals Synthesis, characterization and biological evaluation of formononetin derivatives as novel EGFR inhibitors via inhibiting growth, migration and inducing apoptosis in breast cancer cell line

RSC Advances ◽  
2017 ◽  
Vol 7 (76) ◽  
pp. 48404-48419 ◽  
Author(s):  
Hong-Yan Lin ◽  
Wen-Xue Sun ◽  
Chao-Sai Zheng ◽  
Hong-Wei Han ◽  
Xue Wang ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cell Proliferation ◽  
Cell Line ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Breast Cancer Cell Line ◽  
Cancer Cell Line ◽  
Biological Evaluation ◽  
Induced Apoptosis ◽  
Line P

Novel formononetin derivative 4v inhibited MDA-MB-231 cell proliferation, migration and induced apoptosis through targeting EGFR.

HTS-FTIR spectroscopy allows the classification of polyphenols according to their differential effects on the MDA-MB-231 breast cancer cell line

The Analyst ◽  
2017 ◽  
Vol 142 (8) ◽  
pp. 1244-1257 ◽  
Author(s):  
A. Mignolet ◽  
V. Mathieu ◽  
E. Goormaghtigh
Keyword(s):  
Breast Cancer ◽  
Ftir Spectroscopy ◽  
Cell Line ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Breast Cancer Cell Line ◽  
Cancer Cell Line ◽  
Differential Effects ◽  
Line P

FTIR-based classification of the effect of polyphenols on a breast cancer cell line.

scholarly journals Cyanidin 3-glycoside induced apoptosis in MCF-7 breast cancer cell line

2020 ◽  
Author(s):  
Seyed Mirmalek ◽  
Sholeh Faraji ◽  
Sanaz Ranjbaran ◽  
Hoda Aryan ◽  
Hamid Arani ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cell Line ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Breast Cancer Cell Line ◽  
Cancer Cell Line ◽  
Induced Apoptosis ◽  
Mcf 7

scholarly journals Novel pH-sensitive and biodegradable micelles for the combined delivery of doxorubicin and conferone to induce apoptosis in MDA-MB-231 breast cancer cell line

RSC Advances ◽  
2020 ◽  
Vol 10 (49) ◽  
pp. 29228-29246 ◽  
Author(s):  
Akram Rahmani ◽  
Hassan Zavvar Mousavi ◽  
Roya Salehi ◽  
Ahmad Bagheri
Keyword(s):  
Breast Cancer ◽  
Drug Delivery ◽  
Cell Line ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Cancer Chemotherapy ◽  
Breast Cancer Cell Line ◽  
Cancer Cell Line ◽  
Ph Sensitive ◽  
Line P

pH-sensitive micelles are desirable for co-drug delivery in cancer chemotherapy.

scholarly journals Effects of FSTL1 on cell proliferation in breast cancer cell line MDA-MB-231 and its brain metastatic variant MDA-MB-231-BR

2017 ◽  
Vol 38 (5) ◽  
pp. 3001-3010 ◽  
Author(s):  
Jiaqiang An ◽  
Lulu Wang ◽  
Yuanli Zhao ◽  
Qiang Hao ◽  
Ying Zhang ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cell Proliferation ◽  
Cell Line ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Breast Cancer Cell Line ◽  
Cancer Cell Line ◽  
Metastatic Variant

scholarly journals Apoptosis and Antioxidant Activities of Catharanthus rosues [L] G.Don Extract on Breast Cancer Cell Line

2010 ◽  
Vol 1 (2) ◽  
pp. 99
Author(s):  
Wahyu Widowati ◽  
Tjandrawati Mozef ◽  
Chandra Risdian ◽  
Hana Ratnawati ◽  
Susi Tjahyani ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Antioxidant Activity ◽  
Anticancer Activity ◽  
Cell Line ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Catharanthus Roseus ◽  
Breast Cancer Cell Line ◽  
Cancer Cell Line ◽  
Induced Apoptosis

Tapak dara or Madagascar Periwinkle (Catharanthus roseus [L] G.Don), a natural plant, is empirically reported to have promising anticancer activity. To elucidate its mechanism, a research was conducted to investigate the possible ethanol extract of  C. roseus in inducing apoptosis on breast cancer cell line (T47D). Antioxidant activity of C. roseus was investigated as well. Sub-G1 flowcytometric apoptotic analysis result showed that extract of C. roseus at 6.25 μg/mL induced apoptosis for 26.365%. Increasing extract concentration resulted an increasing apoptotic level as well, extract at concentration of 12.5 μg/mL induced apoptosis for 22.235%.  Meanwhile doxorubicin at concentration of 10 μg/mL induced apoptosis for 36.055%. The antioxidant activity was determined by using in vitro assay: inhibition of  2,2-diphenyl-1-picrylhydrazyl (DPPH) scavenging activity. Antioxidant activity of C. roseus extract were compared to quercetin and butylated hydroxyanisol (BHA), as positive controls.  The results showed that DPPH IC50 of C. roseus extract, quercetin and BHA were 358.411 μg/mL, 19.200 μg/mL  and  94.178 μg/mL, respectively. We suggest that C. roseus extract had a potential anticancer activity by inducing apoptosis.Key words : antioxidant, DPPH, Catharanthus roseus, apoptosis, breast cancer, T47D

scholarly journals The tetrameric peptide LfcinB (20–25)4 derived from bovine lactoferricin induces apoptosis in the MCF-7 breast cancer cell line

RSC Advances ◽  
2019 ◽  
Vol 9 (36) ◽  
pp. 20497-20504 ◽  
Author(s):  
Jorge Rodríguez Guerra ◽  
Andrea Barragán Cárdenas ◽  
Alejandra Ochoa-Zarzosa ◽  
Joel López Meza ◽  
Adriana Umaña Pérez ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cell Line ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Breast Cancer Cell Line ◽  
Cytotoxic Effect ◽  
Cancer Cell Line ◽  
Bovine Lactoferricin ◽  
Line P ◽  
Mcf 7

The cytotoxic effect of the tetrameric peptide LfcinB (20–25)4 against breast cancer cell line ATCC® HTB-22™ (MCF-7) was evaluated.

Leccinum vulpinum Watling induces DNA damage, decreases cell proliferation and induces apoptosis on the human MCF-7 breast cancer cell line

2016 ◽  
Vol 90 ◽  
pp. 45-54 ◽  
Author(s):  
Filipa S. Reis ◽  
Diana Sousa ◽  
Lillian Barros ◽  
Anabela Martins ◽  
Patricia Morales ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cell Proliferation ◽  
Dna Damage ◽  
Cell Line ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Breast Cancer Cell Line ◽  
Cancer Cell Line ◽  
Mcf 7
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