Reaction engineering of biocatalytic (S)-naproxen synthesis integrating in-line process monitoring by Raman spectroscopy

2017 ◽  
Vol 2 (4) ◽  
pp. 531-540 ◽  
Author(s):  
M. Aßmann ◽  
A. Stöbener ◽  
C. Mügge ◽  
S. K. Gaßmeyer ◽  
L. Hilterhaus ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Chemical Synthesis ◽  
Process Monitoring ◽  
Environmentally Friendly ◽  
Reaction Engineering ◽  
Line Process ◽  
Arylmalonate Decarboxylase

Biocatalytic (S)-naproxen synthesis using an (S)-selective arylmalonate decarboxylase mutant (AMDase G74C/M159L/C188G/V43I/A125P/V156L, AMDase-CLGIPL) exposes a promising environmentally friendly alternative to conventional chemical synthesis strategies.

A Hybrid Methodology For On-Line Process Monitoring

2004 ◽  
Vol 2 (1) ◽  
Author(s):  
Rakesh Kumar ◽  
Avinash M. Jade ◽  
Valadi K. Jayaraman ◽  
Bhaskar D. Kulkarni
Keyword(s):  
Process Monitoring ◽  
Current Practice ◽  
Locally Linear Embedding ◽  
Support Vector ◽  
Nonlinear Dimensionality Reduction ◽  
Hybrid Strategy ◽  
Vector Machines ◽  
On Line ◽  
Line Process

A hybrid strategy of using (i) locally linear embedding for nonlinear dimensionality reduction of high dimensional data and (ii) support vector machines for classification of the resultant features is proposed as a robust methodology for process monitoring. Illustrative examples substantiate the methodology vis-à-vis current practice.

An Integrated Rule-Based/Algorithmic Architecture for On-Line Process Monitoring and Reactive Control

1992 ◽  
Vol 25 (28) ◽  
pp. 313-317
Author(s):  
Bruce H. Krogh ◽  
C.J. Paul ◽  
Dwo-Wen Yan ◽  
Jay K. Strosnider ◽  
Lawrence E. Holloway
Keyword(s):  
Process Monitoring ◽  
Reactive Control ◽  
Rule Based ◽  
On Line ◽  
Line Process

OPC model space approach to in-line process monitoring structures

2009 ◽  
Author(s):  
Romuald Sabatier ◽  
Antonio Di Giacomo ◽  
Caroline Fossati ◽  
Salah Bourennane
Keyword(s):  
Process Monitoring ◽  
Model Space ◽  
Line Process ◽  
Space Approach
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