Label-free tracking of nanosized graphene oxide cellular uptake by confocal Raman microscopy

The Analyst ◽  
2018 ◽  
Vol 143 (15) ◽  
pp. 3686-3692 ◽  
Author(s):  
Marianna Eliášová Sohová ◽  
Michal Bodík ◽  
Peter Siffalovic ◽  
Nikola Bugárová ◽  
Martina Labudová ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Cellular Uptake ◽  
Cancer Diagnostics ◽  
Raman Microscopy ◽  
Two Dimensional ◽  
Confocal Raman Microscopy ◽  
Label Free ◽  
Confocal Raman ◽  
Diagnostics And Therapy

Graphene oxide (GO), a partially oxidized two-dimensional allotrope of carbon, is an attractive nanocarrier for cancer diagnostics and therapy.

scholarly journals Label-Free Live-Cell Imaging with Confocal Raman Microscopy

2012 ◽  
Vol 102 (2) ◽  
pp. 360-368 ◽  
Author(s):  
Katharina Klein ◽  
Alexander M. Gigler ◽  
Thomas Aschenbrenner ◽  
Roberto Monetti ◽  
Wolfram Bunk ◽  
...  
Keyword(s):  
Live Cell Imaging ◽  
Cell Imaging ◽  
Raman Microscopy ◽  
Live Cell ◽  
Confocal Raman Microscopy ◽  
Label Free ◽  
Confocal Raman

scholarly journals Label-free detection of anticancer drug paclitaxel in living cells by confocal Raman microscopy

2013 ◽  
Vol 102 (11) ◽  
pp. 113701 ◽  
Author(s):  
H. Salehi ◽  
L. Derely ◽  
A.-G. Vegh ◽  
J.-C. Durand ◽  
C. Gergely ◽  
...  
Keyword(s):  
Anticancer Drug ◽  
Living Cells ◽  
Raman Microscopy ◽  
Confocal Raman Microscopy ◽  
Label Free ◽  
Label Free Detection ◽  
Confocal Raman

scholarly journals Label-free live cell imaging by Confocal Raman Microscopy identifies CHO host and producer cell lines

2016 ◽  
Vol 12 (1) ◽  
pp. 1600037 ◽  
Author(s):  
Batirtze Prats Mateu ◽  
Eva Harreither ◽  
Markus Schosserer ◽  
Verena Puxbaum ◽  
Elisabeth Gludovacz ◽  
...  
Keyword(s):  
Cell Lines ◽  
Live Cell Imaging ◽  
Cell Imaging ◽  
Raman Microscopy ◽  
Live Cell ◽  
Confocal Raman Microscopy ◽  
Label Free ◽  
Producer Cell ◽  
Confocal Raman

scholarly journals Temporal Imaging of Live Cells by High-Speed Confocal Raman Microscopy

Materials ◽  
2021 ◽  
Vol 14 (13) ◽  
pp. 3732
Author(s):  
Jeon Woong Kang ◽  
Freddy T. Nguyen ◽  
Niyom Lue
Keyword(s):  
High Speed ◽  
External Perturbation ◽  
Cell Types ◽  
Raman Microscopy ◽  
Live Cells ◽  
Confocal Raman Microscopy ◽  
Label Free ◽  
Minimal Sample ◽  
Confocal Raman

Label-free live cell imaging was performed using a custom-built high-speed confocal Raman microscopy system. For various cell types, cell-intrinsic Raman bands were monitored. The high-resolution temporal Raman images clearly delineated the intracellular distribution of biologically important molecules such as protein, lipid, and DNA. Furthermore, optical phase delay measured using quantitative phase microscopy shows similarity with the image reconstructed from the protein Raman peak. This reported work demonstrates that Raman imaging is a powerful label-free technique for studying various biomedical problems in vitro with minimal sample preparation and external perturbation to the cellular system.

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