Visible-light-mediated iodine-catalyzed α-hydroxylation of α-methylene ketones under aerobic conditions

2018 ◽  
Vol 5 (8) ◽  
pp. 1325-1329 ◽  
Author(s):  
Jingya Yang ◽  
Dongtai Xie ◽  
Hongyan Zhou ◽  
Shuwen Chen ◽  
Congde Huo ◽  
...  
Keyword(s):  
Visible Light ◽  
Atmospheric Oxygen ◽  
Substrate Selectivity ◽  
Aerobic Conditions

A visible-light-mediated α-hydroxylation of α-methylene ketones using atmospheric oxygen as a green oxidant has been developed with novel substrate selectivity.

scholarly journals A novel high-content screening approach for the elucidation of C. jejuni biofilm composition and integrity

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Matthew V. X. Whelan ◽  
Jeremy C. Simpson ◽  
Tadhg Ó Cróinín
Keyword(s):  
Atmospheric Oxygen ◽  
Chicken Meat ◽  
Live Cells ◽  
High Throughput Analysis ◽  
Aerobic Conditions ◽  
Poultry Products ◽  
Source Of Infection ◽  
Fluorescent Markers ◽  
Oxygen Conditions ◽  
Bacterial Gastroenteritis

Abstract Background Campylobacter jejuni is the leading cause of bacterial gastroenteritis worldwide and the main source of infection is contaminated chicken meat. Although this important human pathogen is an obligate microaerophile, it must survive atmospheric oxygen conditions to allow transmission from contaminated chicken meat to humans. It is becoming increasingly evident that formation of biofilm plays a key role in the survival of this organism for extended periods on poultry products. We have recently demonstrated a novel inducible model for the study of adherent C. jejuni biofilm formation under aerobic conditions. By taking advantage of supercoiling mediated gene regulation, incubation of C. jejuni with subinhibitory concentrations of the Gyrase B inhibitor novobiocin was shown to promote the consistent formation of metabolically active adherent biofilm. Results In this study, we implement this model in conjunction with the fluorescent markers: TAMRA (live cells) and SytoX (dead cells, eDNA) to develop a novel systematic high-content imaging approach and describe how it can be implemented to gain quantifiable information about the integrity and extracellular polymeric substance (EPS) composition of adherent C. jejuni biofilm in aerobic conditions. We show that this produces a model with a consistent, homogenous biofilm that can be induced and used to screen a range of inhibitors of biofilm adherence and matrix formation. Conclusions This model allows for the first time a high throughput analysis of C. jejuni biofilms which will be invaluable in enabling researchers to develop mechanisms to disrupt these biofilms and reduce the viability of these bacteria under aerobic conditions.

Visible light promoted tandem dehydrogenation-deaminative cyclocondensation under aerobic conditions for the synthesis of 2-aryl benzimidazoles/quinoxalines from ortho-phenylenediamines and arylmethyl/ethyl amines

2021 ◽  
Vol 45 (10) ◽  
pp. 4569-4573
Author(s):  
Firdoos Ahmad Sofi ◽  
Rohit Sharma ◽  
Ravi Rawat ◽  
Asit K. Chakraborti ◽  
Prasad V. Bharatam
Keyword(s):  
Visible Light ◽  
Aerobic Conditions

Visible light promoted tandem dehydrogenation-deaminative cyclocondensation of arylmethyl/ethyl amines with ortho-phenylenediamines under aerobic conditions is reported for the synthesis of 2-aryl benzimidazoles/quinoxalines.

scholarly journals Visible‐Light‐Driven, One‐pot Amide Synthesis Catalyzed by the B 12 Model Complex under Aerobic Conditions

ChemPlusChem ◽  
2019 ◽  
Vol 84 (3) ◽  
pp. 236-236 ◽  
Author(s):  
Hui Tian ◽  
Hisashi Shimakoshi ◽  
Toshikazu Ono ◽  
Yoshio Hisaeda
Keyword(s):  
Visible Light ◽  
One Pot ◽  
Aerobic Conditions ◽  
Amide Synthesis ◽  
Model Complex ◽  
Visible Light Driven

Visible-light-mediated oxidative arylation of vinylarenes under aerobic conditions

2015 ◽  
Vol 5 (2) ◽  
pp. 830-834 ◽  
Author(s):  
Meijie Bu ◽  
Teng Fei Niu ◽  
Chun Cai
Keyword(s):  
Visible Light ◽  
Efficient Method ◽  
Aerobic Conditions

A mild and efficient method for the photocatalytic oxidative arylation of vinylarenes to generate 1,2-diarylated ethanones has been developed.

Visible-light-promoted oxidative difunctionalization of alkenes with sulfonyl chlorides to access β-keto sulfones under aerobic conditions

2017 ◽  
Vol 58 (37) ◽  
pp. 3667-3671 ◽  
Author(s):  
Teng-fei Niu ◽  
Jing Cheng ◽  
Chang-li Zhuo ◽  
Ding-yun Jiang ◽  
Xing-ge Shu ◽  
...  
Keyword(s):  
Visible Light ◽  
Aerobic Conditions ◽  
Sulfonyl Chlorides ◽  
Oxidative Difunctionalization

scholarly journals Carbon nitride as a heterogeneous visible-light photocatalyst for the Minisci reaction and coupling to H2 production

2019 ◽  
Vol 55 (93) ◽  
pp. 14007-14010 ◽  
Author(s):  
Arjun Vijeta ◽  
Erwin Reisner
Keyword(s):  
Visible Light ◽  
Electron Acceptor ◽  
Carbon Nitride ◽  
Atmospheric Oxygen ◽  
H2 Production ◽  
Nitride Powder ◽  
Co Catalyst ◽  
Visible Light Photocatalyst ◽  
Type Coupling

Cyanamide functionalised carbon nitride powder is reported as a photocatalyst for direct Minisci-type coupling of heteroarenes with ethers, alcohols, and amides using atmospheric oxygen or a hydrogen evolving co-catalyst as an electron acceptor.

Synthesis of 6-Thiocyanatophenanthridines by Visible-Light- and Air-Promoted Radical Thiocyanation of 2-Isocyanobiphenyls

Synlett ◽  
2017 ◽  
Vol 29 (02) ◽  
pp. 176-180 ◽  
Author(s):  
Manjula Singh ◽  
Arvind Yadav ◽  
Lal Yadav ◽  
R. Singh
Keyword(s):  
Natural Resources ◽  
Visible Light ◽  
Room Temperature ◽  
Atmospheric Oxygen ◽  
Ammonium Thiocyanate ◽  
Radical Cyclization ◽  
Eosin Y ◽  
One Pot ◽  
Metal Free

A convenient, efficient, and metal-free synthesis of 6-thiocyanatophenanthridines by visible-light- and air-mediated, eosin Y-catalyzed, sequential radical cyclization and aromatization of 2-isocyanobiphenyls with ammonium thiocyanate is reported. Advantageously, the protocol utilizes inexpensive, clean, and sustainable natural resources such as visible light and atmospheric oxygen at room temperature in a one-pot procedure.

scholarly journals Substrate Selectivity of a 3-Nitrophenol-Induced Metabolic System in Pseudomonas putida 2NP8 Transforming Nitroaromatic Compounds into Ammonia under Aerobic Conditions

2001 ◽  
Vol 67 (3) ◽  
pp. 1388-1391 ◽  
Author(s):  
Jian-Shen Zhao ◽  
Owen P. Ward
Keyword(s):  
Pseudomonas Putida ◽  
Enzyme System ◽  
Nitroaromatic Compounds ◽  
Substrate Selectivity ◽  
Ammonia Production ◽  
Metabolic System ◽  
Aerobic Conditions ◽  
Nitrobenzoic Acid ◽  
In Cells

ABSTRACT The 3-nitrophenol-induced enzyme system in cells ofPseudomonas putida 2NP8 manifested a wide substrate range in transforming nitroaromatic compounds through to ammonia production. All of the 30 mono- or dinitroaromatic substrates except 4-nitrophenol, 2,4-dinitrophenol, 2,4,6-trinitrophenol, 3-nitroaniline, 2-nitrobenzoic acid, and 2-nitrofuran were quickly transformed. Ammonia production from most nitroaromatic substrates appeared to be stoichiometric.

Sign in / Sign up

Export Citation Format

Share Document