scholarly journals Real-time simultaneous detection of microbial contamination and determination of an ultra low-content active pharmaceutical ingredient in tazarotene gel by near-infrared spectroscopy

RSC Advances ◽  
2018 ◽  
Vol 8 (48) ◽  
pp. 27037-27044 ◽  
Author(s):  
Qian Xie ◽  
Ruanqi Wu ◽  
Xiaoxiao Zhong ◽  
Yanhong Dong ◽  
Qi Fan

This paper proposes a real-time and non-destructive strategy for sensitive and simultaneous detection of microbial contamination and determination of an ultra low-content active pharmaceutical ingredient in tazarotene gel by NIR spectroscopy.

2014 ◽  
Vol 43 (24) ◽  
pp. 8200-8214 ◽  
Author(s):  
Marena Manley

Principles, interpretation and applications of near-infrared (NIR) spectroscopy and NIR hyperspectral imaging are reviewed.


1995 ◽  
Vol 3 (2) ◽  
pp. 89-95 ◽  
Author(s):  
Tongming Jin ◽  
Ling Liu ◽  
Xiaowei Tang ◽  
Hang Chen

The feasibility of using a non-destructive method to differentiate male (M), female (F) and dead (D) worm cocoons of silkworms has been studied with near infrared (NIR) spectroscopy over the region 680–1235 nm on a sample set of 205 fresh cocoons. On the basis of the spectral data of the first and second derivatives, characteristic vectors were extracted by multiple linear regression and a Bayes critical function was established. This function was used to test 375 samples and the success rate was 95.7%. This method of sex judging is thus preferable to the conventional use of the weight and size of a cocoon which achieved a success rate of only 82.9% on the same samples. Experiments showed that the differences between NIR spectra of M and F cocoons mainly result from the property of silkworm cocoons rather than their incunabulum.


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