scholarly journals Antimicrobial peptide based magnetic recognition elements and Au@Ag-GO SERS tags with stable internal standards: a three in one biosensor for isolation, discrimination and killing of multiple bacteria in whole blood

2018 ◽  
Vol 9 (47) ◽  
pp. 8781-8795 ◽  
Author(s):  
Kaisong Yuan ◽  
Qingsong Mei ◽  
Xinjie Guo ◽  
Youwei Xu ◽  
Danting Yang ◽  
...  
Keyword(s):  
Antimicrobial Peptide ◽  
Whole Blood ◽  
Bacterial Pathogens ◽  
Internal Standards ◽  
Recognition Elements ◽  
Sers Tags

A SERS based biosensor has been developed for isolation, detection and killing of multiple bacterial pathogens.

scholarly journals Correction: Antimicrobial peptide based magnetic recognition elements and Au@Ag-GO SERS tags with stable internal standards: a three in one biosensor for isolation, discrimination and killing of multiple bacteria in whole blood

2019 ◽  
Vol 10 (2) ◽  
pp. 635-635 ◽  
Author(s):  
Kaisong Yuan ◽  
Qingsong Mei ◽  
Xinjie Guo ◽  
Youwei Xu ◽  
Danting Yang ◽  
...  
Keyword(s):  
Antimicrobial Peptide ◽  
Whole Blood ◽  
Internal Standards ◽  
Recognition Elements ◽  
Sers Tags

Correction for ‘Antimicrobial peptide based magnetic recognition elements and Au@Ag-GO SERS tags with stable internal standards: a three in one biosensor for isolation, discrimination and killing of multiple bacteria in whole blood’ by Kaisong Yuan et al., Chem. Sci., 2018, DOI: 10.1039/c8sc04637a.

scholarly journals In vitroeffectiveness of the antimicrobial peptide eCATH1 against antibiotic-resistant bacterial pathogens of horses

2013 ◽  
Vol 350 (2) ◽  
pp. 216-222 ◽  
Author(s):  
Margot Schlusselhuber ◽  
Kristen Guldbech ◽  
Corinne Sevin ◽  
Matthias Leippe ◽  
Sandrine Petry ◽  
...  
Keyword(s):  
Antimicrobial Peptide ◽  
Bacterial Pathogens ◽  
Antibiotic Resistant

Comparing the effect of isotopically labeled or structural analog internal standards on the performance of a LC-MS/MS method to determine ciclosporin A, everolimus, sirolimus and tacrolimus in whole blood

2016 ◽  
Vol 54 (3) ◽  
Author(s):  
Henar Valbuena ◽  
Maria Shipkova ◽  
Sophie-Maria Kliesch ◽  
Simon Müller ◽  
Eberhard Wieland
Keyword(s):  
Mass Spectrometry ◽  
Whole Blood ◽  
Matrix Effects ◽  
Structural Analog ◽  
Immunosuppressive Drugs ◽  
Tandem Mass ◽  
Internal Standards ◽  
Chromatography Tandem Mass Spectrometry ◽  
Ciclosporin A ◽  
Liquid Chromatography Tandem Mass

AbstractLiquid chromatography-tandem mass spectrometry (LC-MS/MS) is routinely used for analysis of immunosuppressive drugs. This study investigated whether replacing analog internal standards (ANISs) with isotopically labeled internal standards (ILISs) has an impact on the performance of a LC-MS/MS method for the quantification of tacrolimus (TAC), sirolimus (SIR), ciclosporin A (CsA) and everolimus (EVE) in whole blood.Following hemolysis, protein precipitation, and extraction with either ANISs (ascomycin, desmethoxy-rapamycin, CsD), or ILISs (TAC-Within-day imprecision was <10%, between-day <8%, and trueness 91%–110% for all the analytes with both ISs. No carryover or matrix effects were observed. The median accuracy was −2.1% for CsA, 9.1% for EVE, 12.2% for SIR, and −1.2% for TAC with the ILISs; and −2% for CsA, 9.8% for EVE, 11.4% for SIR, and 0.2% for TAC with the ANISs. Results of patient and proficiency testing samples were not statistically different.: Although ILISs are generally considered superior to ANISs, they may not be always essential. When optimizing a LC-MS/MS method other factors must be also considered.

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