Lipid nanoparticles – Metvan: revealing a novel way to deliver a vanadium compound to bone cancer cells

2019 ◽  
Vol 43 (45) ◽  
pp. 17726-17734 ◽  
Author(s):  
M. L. Cacicedo ◽  
M. C. Ruiz ◽  
S. Scioli-Montoto ◽  
M. E. Ruiz ◽  
M. A. Fernández ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Bone Cancer ◽  
Lipid Nanoparticles ◽  
Antitumor Efficacy ◽  
Vanadium Compound

A new Metvan-NLC compound was developed to improve Metvan's biopharmaceutical profile and antitumor efficacy.

In Vitro and In Vivo Antitumor Efficacy of Docetaxel and Sorafenib Combination in Human Pancreatic Cancer Cells

2010 ◽  
Vol 999 (999) ◽  
pp. 1-11
Author(s):  
P. Ulivi ◽  
C. Arienti ◽  
W. Zoli ◽  
M. Scarsella ◽  
S. Carloni ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Cancer Cells ◽  
Antitumor Efficacy ◽  
Human Pancreatic Cancer ◽  
Pancreatic Cancer Cells

scholarly journals Osteosarcoma and Metastasis Associated Bone Degradation—A Tale of Osteoclast and Malignant Cell Cooperativity

2021 ◽  
Vol 22 (13) ◽  
pp. 6865
Author(s):  
Kirstine Sandal Nørregaard ◽  
Henrik Jessen Jürgensen ◽  
Henrik Gårdsvoll ◽  
Lars Henning Engelholm ◽  
Niels Behrendt ◽  
...  
Keyword(s):  
Bone Metastasis ◽  
Cancer Cells ◽  
Bone Cancer ◽  
Degradation Process ◽  
Cell Types ◽  
Malignant Cell ◽  
Pathological Process ◽  
Course Of Disease ◽  
Bone Degradation ◽  
Primary Bone

Cancer-induced bone degradation is part of the pathological process associated with both primary bone cancers, such as osteosarcoma, and bone metastases originating from, e.g., breast, prostate, and colon carcinomas. Typically, this includes a cancer-dependent hijacking of processes also occurring during physiological bone remodeling, including osteoclast-mediated disruption of the inorganic bone component and collagenolysis. Extensive research has revealed the significance of osteoclast-mediated bone resorption throughout the course of disease for both primary and secondary bone cancer. Nevertheless, cancer cells representing both primary bone cancer and bone metastasis have also been implicated directly in bone degradation. We will present and discuss observations on the contribution of osteoclasts and cancer cells in cancer-associated bone degradation and reciprocal modulatory actions between these cells. The focus of this review is osteosarcoma, but we will also include relevant observations from studies of bone metastasis. Additionally, we propose a model for cancer-associated bone degradation that involves a collaboration between osteoclasts and cancer cells and in which both cell types may directly participate in the degradation process.

scholarly journals Effects of alendronate and interferon-γ on bone cancer cells in vitro

2018 ◽  
Vol 4 (1) ◽  
pp. 1427306 ◽  
Author(s):  
Andrew W. Barone ◽  
Gabriela Fernandes ◽  
Rosemary Dziak ◽  
Meritxell Huch
Keyword(s):  
Cancer Cells ◽  
Bone Cancer ◽  
Interferon Γ

scholarly journals Cholesteryl butyrate solid lipid nanoparticles inhibit the adhesion and migration of colon cancer cells

2012 ◽  
Vol 166 (2) ◽  
pp. 587-601 ◽  
Author(s):  
R Minelli ◽  
L Serpe ◽  
P Pettazzoni ◽  
V Minero ◽  
G Barrera ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Cancer Cells ◽  
Solid Lipid Nanoparticles ◽  
Lipid Nanoparticles ◽  
Colon Cancer Cells ◽  
Solid Lipid ◽  
And Migration

Piperlongumine potentiates the antitumor efficacy of oxaliplatin through ROS induction in gastric cancer cells

2019 ◽  
Vol 42 (6) ◽  
pp. 847-860 ◽  
Author(s):  
Peichen Zhang ◽  
Lingyan Shi ◽  
Tingting Zhang ◽  
Lin Hong ◽  
Wei He ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Cancer Cells ◽  
Antitumor Efficacy ◽  
Gastric Cancer Cells

scholarly journals Cytotoxic effects of gemcitabine-loaded solid lipid nanoparticles in pancreatic cancer cells

2020 ◽  
Vol 55 ◽  
pp. 101374 ◽  
Author(s):  
Kevin O. Affram ◽  
Taylor Smith ◽  
Edward Ofori ◽  
Sunil Krishnan ◽  
Patrick Underwood ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Cancer Cells ◽  
Solid Lipid Nanoparticles ◽  
Lipid Nanoparticles ◽  
Cytotoxic Effects ◽  
Solid Lipid ◽  
Pancreatic Cancer Cells
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