scholarly journals Hybrid polymer/porous silicon nanofibers for loading and sustained release of synthetic DNA-based responsive devices

Nanoscale ◽  
2020 ◽  
Vol 12 (4) ◽  
pp. 2333-2339 ◽  
Author(s):  
Jonathan M. Zuidema ◽  
Alessandro Bertucci ◽  
Jinyoung Kang ◽  
Michael J. Sailor ◽  
Francesco Ricci
Keyword(s):  
Porous Silicon ◽  
Sustained Release ◽  
Silicon Nanoparticles ◽  
Hybrid Polymer ◽  
Polymer Nanofibers ◽  
Synthetic Dna ◽  
Hybrid Nanofibers ◽  
Porous Silicon Nanoparticles

Synthetic DNA-based oligonucleotides are loaded into porous silicon nanoparticles and incorporated into polymer nanofibers. The functionality of these input-responsive nanodevices is retained following release from the hybrid nanofibers.

Dual-drug delivery by porous silicon nanoparticles for improved cellular uptake, sustained release, and combination therapy

2015 ◽  
Vol 16 ◽  
pp. 206-214 ◽  
Author(s):  
Chang-Fang Wang ◽  
Ermei M. Mäkilä ◽  
Martti H. Kaasalainen ◽  
Marja V. Hagström ◽  
Jarno J. Salonen ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Porous Silicon ◽  
Combination Therapy ◽  
Sustained Release ◽  
Cellular Uptake ◽  
Silicon Nanoparticles ◽  
Porous Silicon Nanoparticles ◽  
Dual Drug

Fusogenic porous silicon nanoparticles as a broad-spectrum immunotherapy against bacterial infections

2021 ◽  
Author(s):  
Byungji Kim ◽  
Qinglin Yang ◽  
Leslie W. Chan ◽  
Sangeeta N. Bhatia ◽  
Erkki Ruoslahti ◽  
...  
Keyword(s):  
Porous Silicon ◽  
Broad Spectrum ◽  
Therapeutic Efficacy ◽  
Bacterial Infections ◽  
Silicon Nanoparticles ◽  
First Line ◽  
Gram Positive ◽  
Gram Negative ◽  
Porous Silicon Nanoparticles

RNAi-mediated immunotherapy provided by fusogenic porous silicon nanoparticles demonstrates superior therapeutic efficacy against both Gram-positive and Gram-negative bacterial infections compared with first-line antibiotics.

scholarly journals Tracking the Fate of Porous Silicon Nanoparticles Delivering a Peptide Payload by Intrinsic Photoluminescence Lifetime

2018 ◽  
Vol 30 (35) ◽  
pp. 1802878 ◽  
Author(s):  
Yusung Jin ◽  
Dokyoung Kim ◽  
Hajung Roh ◽  
Sojeong Kim ◽  
Sazid Hussain ◽  
...  
Keyword(s):  
Porous Silicon ◽  
Silicon Nanoparticles ◽  
Porous Silicon Nanoparticles ◽  
Photoluminescence Lifetime

scholarly journals Ex vivo biodistribution of gallium-68-labeled porous silicon nanoparticles

2020 ◽  
Vol 1439 ◽  
pp. 012035
Author(s):  
V K Tishchenko ◽  
V. M. Petriev ◽  
A A Mikhailovskaya ◽  
O A Smoryzanova ◽  
A V Kabashin ◽  
...  
Keyword(s):  
Porous Silicon ◽  
Silicon Nanoparticles ◽  
Ex Vivo ◽  
Porous Silicon Nanoparticles ◽  
Gallium 68 ◽  
Ex Vivo Biodistribution
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