One stone two birds: cobalt-catalyzed in situ generation of isocyanates and benzyl alcohols for the synthesis of N-aryl carbamates

2019 ◽  
Vol 17 (24) ◽  
pp. 5891-5896 ◽  
Author(s):  
Sida Li ◽  
Ruhima Khan ◽  
Xia Zhang ◽  
Yong Yang ◽  
Zheting Wang ◽  
...  

An efficient method for the synthesis of N-aryl carbamates from N-Boc-protected amines has been developed.

2018 ◽  
Vol 14 ◽  
pp. 2308-2312 ◽  
Author(s):  
Edwin Alfonzo ◽  
Jesse W L Mendoza ◽  
Aaron B Beeler

A one-pot synthesis of epoxides from commercially available benzyl alcohols and aldehydes is described. The reaction proceeds through in situ generation of sulfonium salts from benzyl alcohols and their subsequent deprotonation for use in Corey–Chaykovsky epoxidation of aldehydes. The generality of the method is exemplified by the synthesis of 34 epoxides that were made from an array of electronically and sterically varied alcohols and aldehydes.


2014 ◽  
Vol 67 (9) ◽  
pp. 1360 ◽  
Author(s):  
Jia Cao ◽  
Patrick Perlmutter

A highly efficient method for the conversion of primary tosylates into the corresponding iodides is outlined. The method involves heating a neat mixture of the tosylate and solid sodium iodide in a microwave cavity. Reaction times are short, usually about 60 minutes, delivering high yields. This procedure is especially useful for the in situ generation of volatile primary iodides, and for most of the primary iodides, the crude product is sufficiently pure.


ChemInform ◽  
2003 ◽  
Vol 34 (26) ◽  
Author(s):  
Mohammad Ali Zolfigol ◽  
Arash Ghorbani Choghamarani ◽  
Solmaz Dialameh ◽  
Majid M. Sadeghi ◽  
Iraj Mohammadpoor-Baltork ◽  
...  

2003 ◽  
Vol 2003 (1) ◽  
pp. 18-20 ◽  
Author(s):  
Mohammad Ali Zolfigol ◽  
Arash Ghorbani Choghamarani ◽  
Solmaz Dialameh ◽  
Majid M. Sadeghi ◽  
Iraj Mohammadpoor-Baltork ◽  
...  

A combination of inorganic chloride salts [e.g. AlCl3, ZrCl4, and ZnCl2] and sodium nitrite in the presence of wet SiO2 was used as an effective oxidising agent for the oxidation of dihydropyridines to their corresponding pyridine derivatives under mild and heterogeneous conditions in moderate to excellent yields.


Author(s):  
Kazumasa Funabiki ◽  
Toshiya Gotoh ◽  
Ryunosuke Kani ◽  
Toshiyasu Inuzuka ◽  
Yasuhiro Kubota

A highly diastereo- and enantioselective organocatalytic method to synthesise erythritols bearing a trifluoromethyl group has been investigated.


2020 ◽  
Vol 24 ◽  
Author(s):  
Wengui Wang ◽  
Shoufeng Wang

Abstract:: Minisci-type reactions have become widely known as reactions that involve the addition of carbon-centered radicals to basic heteroarenes followed by formal hydrogen atom loss. While the originally developed protocols for radical generation remain in active use today, in recent years by a new array of radical generation strategies allow use of a wider variety of radical precursors that often operate under milder and more benign conditions. New transformations based on free radical reactivity are now available to a synthetic chemist looking to utilize a Minisci-type reaction. Radical-generation methods based on photoredox catalysis and electrochemistry, which utilize thermal cleavage or the in situ generation of reactive radical precursors, have become popular approaches. Our review will cover the remarkably literature that has appeared on this topic in recent 5 years, from 2015-01 to 2020-01, in an attempt to provide guidance to the synthetic chemist, on both the challenges that have been overcome and applications in organic synthesis.


2021 ◽  
Author(s):  
Thomas Richards ◽  
Jonathan H. Harrhy ◽  
Richard J. Lewis ◽  
Alexander G. R. Howe ◽  
Grzegorz M. Suldecki ◽  
...  

2021 ◽  
Vol 23 (3) ◽  
pp. 1130-1134
Author(s):  
Haibo Mei ◽  
Li Wang ◽  
Romana Pajkert ◽  
Qian Wang ◽  
Jingcheng Xu ◽  
...  

2014 ◽  
Vol 1038 ◽  
pp. 75-81
Author(s):  
Bernd Niese ◽  
Philipp Amend ◽  
Uwe Urmoneit ◽  
Stephan Roth ◽  
Michael Schmidt

Embedding stereolithography (eSLA) is an additive, hybrid process, which provides a flexible production of 3D components and the ability to integrate electrical and optical conductive structures and functional components within parts. However, the embedding of conductive circuits in stereolithography (SLA) parts assumes usage of process technologies, which enables their direct integration of conductive circuits during the layer-wise building process. In this context, a promising method for in-situ generation of conductive circuits is dispensing of conductive adhesive on the current surface of the SLA part and its subsequent sintering. In this paper, the laser sintering (λ = 355 nm) of conductive adhesive mainly consisting of silver nanoparticles is investigated. The work intends to evaluate the curing behavior of the conductive adhesive, the beam-matter-interactions and the thermal damage of the SLA substrate. The investigations revealed a fast and flexible laser sintering process for the generation of conductive circuits with sufficient electrical conductivity and sufficient current capacity load. In this context, a characterization of the conductive structures is done by measuring their electrical resistance and their potential current capacity load.


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