Activatable fluorescent probes for hydrolase enzymes based on coumarin–hemicyanine hybrid fluorophores with large Stokes shifts

2020 ◽  
Vol 56 (42) ◽  
pp. 5617-5620
Author(s):  
Hiroyoshi Fujioka ◽  
Shin-nosuke Uno ◽  
Mako Kamiya ◽  
Ryosuke Kojima ◽  
Kai Johnsson ◽  
...  
Keyword(s):  
Fluorescent Probes ◽  
Stokes Shift ◽  
Fluorescence Probes ◽  
Chemical Modifications ◽  
Large Stokes Shift ◽  
Stokes Shifts

We show that the equilibrium of intramolecular spirocyclization of coumarin–hemicyanine hybrid fluorophores can be finely tuned by means of chemical modifications to develop activatable fluorescence probes for hydrolases with large Stokes shift.

scholarly journals Novel alkyl chain-based fluorescent probes with large Stokes shifts used for imaging the cell membrane and mitochondria in different living cell lines

RSC Advances ◽  
2017 ◽  
Vol 7 (26) ◽  
pp. 16087-16091 ◽  
Author(s):  
Fangfang Meng ◽  
Yong Liu ◽  
Jie Niu ◽  
Weiying Lin
Keyword(s):  
Cell Membrane ◽  
Cell Lines ◽  
Fluorescent Probes ◽  
Living Cell ◽  
Alkyl Chain ◽  
Stokes Shift ◽  
Alkyl Chains ◽  
Large Stokes Shift ◽  
Stokes Shifts

In this study, we describe two novel alkyl chains-based fluorescent probes with large Stokes shift. Both probes have been successfully applied for sensing the cell membrane and mitochondria in different living cell lines.

Substitution nitrogen for chlorine of heptamethine cyanines for large Stokes shift fluorescent probes

2016 ◽  
Vol 57 (8) ◽  
pp. 932-936 ◽  
Author(s):  
Lihui Zheng ◽  
Liqiu Wang ◽  
Pengjun Wang ◽  
Qi Sun ◽  
Xuelong Liu ◽  
...  
Keyword(s):  
Fluorescent Probes ◽  
Stokes Shift ◽  
Large Stokes Shift

scholarly journals Novel rhodamine dye with large Stokes shifts by fusing the 1,4-diethylpiperazine moiety and its applications in fast detection of Cu2+

RSC Advances ◽  
2020 ◽  
Vol 10 (62) ◽  
pp. 38038-38044
Author(s):  
Jin Gong ◽  
Chang Liu ◽  
Xiaojie Jiao ◽  
Song He ◽  
Liancheng Zhao ◽  
...  
Keyword(s):  
Stokes Shift ◽  
Fast Detection ◽  
Large Stokes Shift ◽  
Rhodamine Dye ◽  
Stokes Shifts ◽  
Rhodamine Dyes

A novel NIR rhodamine dye JRQ with large Stokes shift (70 nm) by fusing the 1,4-diethylpiperazine moiety in rhodamine dyes has been synthesized and utilized to design a probe.

Two-photon absorbing 8-hydroxy-benzo[g]coumarins with giant Stokes shifts: an environment-insensitive dye platform for probing biomolecules

2018 ◽  
Vol 6 (27) ◽  
pp. 4446-4452 ◽  
Author(s):  
Sourav Sarkar ◽  
Mithun Santra ◽  
Subhankar Singha ◽  
Yong Woong Jun ◽  
Ye Jin Reo ◽  
...  
Keyword(s):  
Stokes Shift ◽  
Coumarin Derivative ◽  
Large Stokes Shift ◽  
Two Photon ◽  
Stokes Shifts

An 8-hydroxybenzo[g]coumarin derivative with two-photon absorptivity and a large Stokes shift has been highlighted as an environment insensitive dye platform.

Near-infrared fluorescent dyes with large Stokes shifts: light generation in BODIPYs undergoing excited state intramolecular proton transfer

2017 ◽  
Vol 15 (19) ◽  
pp. 4072-4076 ◽  
Author(s):  
Qiang Fei ◽  
Xianfeng Gu ◽  
Yajing Liu ◽  
Ben Shi ◽  
Hengyan Liu ◽  
...  
Keyword(s):  
Excited State ◽  
Proton Transfer ◽  
Near Infrared ◽  
Fluorescent Dyes ◽  
Stokes Shift ◽  
Intramolecular Proton Transfer ◽  
Large Stokes Shift ◽  
Light Generation ◽  
Stokes Shifts

New ESIPT-based BODIPYs are developed to render the NIR emissions with a large Stokes shift.

Novel BODIPY-based fluorescent probes with large Stokes shift for imaging hydrogen sulfide

2019 ◽  
Vol 165 ◽  
pp. 400-407 ◽  
Author(s):  
Xiao-Yan Zhu ◽  
Hao Wu ◽  
Xiao-Feng Guo ◽  
Hong Wang
Keyword(s):  
Hydrogen Sulfide ◽  
Fluorescent Probes ◽  
Stokes Shift ◽  
Large Stokes Shift

Synthesis of a visibly emissive 9-nitro-2,3-dihydro-1H-pyrimido[1,2-a]quinoxalin-5-amine scaffold with large stokes shift and live cell imaging

RSC Advances ◽  
2015 ◽  
Vol 5 (87) ◽  
pp. 70958-70967 ◽  
Author(s):  
Ajay Kanungo ◽  
Dipendu Patra ◽  
Sanghamitra Mukherjee ◽  
Tridib Mahata ◽  
Prakas R. Maulik ◽  
...  
Keyword(s):  
Live Cell Imaging ◽  
Cell Imaging ◽  
Stokes Shift ◽  
Live Cell ◽  
Visible Range ◽  
Large Stokes Shift ◽  
Stokes Shifts

Synthesis and live cell imaging of a novel fluorescent scaffold which is emissive in the visible range with large stokes shifts.

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