Sucrose-mediated heat-stiffening microemulsion-based gel for enzyme entrapment and catalysis

2020 ◽  
Vol 56 (73) ◽  
pp. 10698-10701 ◽  
Author(s):  
Akshi Deshwal ◽  
Himanshu Chitra ◽  
Madhusudan Maity ◽  
Santanu Kumar Pal ◽  
Subhabrata Maiti
Keyword(s):  
Batch Bioreactor ◽  
Microemulsion Based Gel ◽  
Enzyme Entrapment

Formation of a thermo-stiffening microemulsion-based-gel showing the nanoconfinement effect of carbohydrates as an efficient batch bioreactor for entrapped enzymes has been reported.

Simulation of UDMC on a Fed-Batch Bioreactor

1988 ◽  
Author(s):  
Hsin-Ying Lin ◽  
John C. Lewis ◽  
Richard H. Luecke
Keyword(s):  
Fed Batch ◽  
Batch Bioreactor

Formulation and Evaluation of Fish Oil-based Rizatriptan Microemulsion for Intranasal Migraine Treatment

2015 ◽  
Vol 8 (3) ◽  
pp. 2972-2978
Author(s):  
Kanchan P Upadhye ◽  
Divya Senpal ◽  
Minakshee Nimbalwar ◽  
Gouri Dixit
Keyword(s):  
Fish Oil ◽  
Nasal Cavity ◽  
Residence Time ◽  
Stability Study ◽  
Migraine Treatment ◽  
Existence Region ◽  
Microemulsion Based Gel ◽  
Micro Emulsion ◽  
Pseudoternary Phase Diagram

In the present study microemulsion based intranasal gel of rizatriptan using fish oil was prepared for treatment and management of migraine to sustain the drug release and improve the drug residence time in nasal cavity. Fish oil is reported to have antimigraine activity hence it has been used in the present formulation along with cremophore EL as surfactant and Transcutol P as co-surfactant. The pseudoternary phase diagram plotted with these components shown the microemulsion existence region in ratio of (1:9-9:1) surfactant and co-surfactant. The optimized micro-emulsion contained fish oil (45.29%), cremophore E/transcutol P (2:1) and was characterized for pH (6.3±0.02), viscosity (114 ± 3.00cp), % transmittance (99.5 ± 1.01), refractive index (1.335±0.01),). The prepared microemulsion gels were optimized and characterized for in-vitro studies, pH, drug content, rheological studies and stability study. The release of rizatriptan from micro-emulsion gel prepared from carbopol 934 (98.01%) was found to be higher and prolonged than plain gel. Thus, microemulsion based gel was able to prolong drug releaseand improve drug residence time in the nasal cavity. 

Automated sequencing batch bioreactor under extreme peaks of 4-chlorophenol

2003 ◽  
Vol 47 (10) ◽  
pp. 175-181 ◽  
Author(s):  
G. Buitrón ◽  
M.-E. Schoeb ◽  
J. Moreno
Keyword(s):  
Dissolved Oxygen ◽  
Metabolic Activity ◽  
Automated System ◽  
Stable Operation ◽  
High Concentration ◽  
Batch Bioreactor ◽  
On Line ◽  
The Moment ◽  
And Control ◽  
System Operating

The operation of a sequencing batch bioreactor is evaluated when high concentration peaks of a toxic compound (4-chlorophenol, 4CP) are introduced into the reactor. A control strategy based on the dissolved oxygen concentration, measured on line, is utilized. To detect the end of the reaction period, the automated system search for the moment when the dissolved oxygen has passed by a minimum, as a consequence of the metabolic activity of the microorganisms and right after to a maximum due to the saturation of the water (similar to the self-cycling fermentation, SCF, strategy). The dissolved oxygen signal was sent to a personal computer via data acquisition and control using MATLAB and the SIMULINK package. The system operating under the automated strategy presented a stable operation when the acclimated microorganisms (to an initial concentration of 350 mg 4CP/L), were exposed to a punctual concentration peaks of 600 mg 4CP/L. The 4CP concentrations peaks superior or equals to 1,050 mg/L only disturbed the system from a short to a medium term (one month). The 1,400 mg/L peak caused a shutdown in the metabolic activity of the microorganisms that led to the reactor failure. The biomass acclimated with the SCF strategy can partially support the variations of the toxic influent since, at the moment in which the influent become inhibitory, there is a failure of the system.

Control of dissolved oxygen concentration using neural network in a batch bioreactor

2010 ◽  
Vol 20 (4) ◽  
pp. 619-628 ◽  
Author(s):  
Tufan Mete ◽  
Gulay Ozkan ◽  
Hale Hapoglu ◽  
Mustafa Alpbaz
Keyword(s):  
Neural Network ◽  
Dissolved Oxygen ◽  
Oxygen Concentration ◽  
Dissolved Oxygen Concentration ◽  
Batch Bioreactor

scholarly journals Enzyme entrapment in liposomes

FEBS Letters ◽  
1971 ◽  
Vol 14 (2) ◽  
pp. 95-99 ◽  
Author(s):  
G. Gregoriadis ◽  
P.D. Leathwood ◽  
Brenda E. Ryman
Keyword(s):  
Enzyme Entrapment

scholarly journals Implementation of Stir-Speed Adopted Controllers Onto a Batch Bioreactor for Improved Fermentation

IEEE Access ◽  
2021 ◽  
Vol 9 ◽  
pp. 16783-16806
Author(s):  
Jozef Ritonja
Keyword(s):  
Batch Bioreactor

scholarly journals Optimal control of a batch bioreactor for the production of a novel antifungal substance CF66I

2009 ◽  
Vol 8 (21) ◽  
pp. 5702-5710
Author(s):  
Quan Chun Shan ◽  
Li Xin ◽  
Wang Jun Hua ◽  
Zheng Wei ◽  
Fan Sheng Di
Keyword(s):  
Optimal Control ◽  
Antifungal Substance ◽  
Batch Bioreactor

scholarly journals Reuse of treated wastewater using sequencing batch bioreactor for the improvement of wheat growth

2011 ◽  
Vol 1 (3) ◽  
pp. 179-184 ◽  
Author(s):  
Beenish Saba ◽  
Tariq Mahmood ◽  
Bushra Zaman ◽  
Imran Hashmi
Keyword(s):  
Removal Efficiency ◽  
Growth Parameters ◽  
Wheat Variety ◽  
Treatment Plant ◽  
Oxygen Demand ◽  
Laboratory Scale ◽  
Treated Wastewater ◽  
Reclaimed Wastewater ◽  
Attached Growth ◽  
Batch Bioreactor

Reclaimed wastewater reuse for irrigation to crop plants is evaluated in a laboratory-scale experiment to assess growth and water saving potential from natural resources. A prototype laboratory-scale treatment plant was established for this purpose with suspended and attached growth configurations. Chakwal wheat variety was selected to examine growth parameters. The removal of chemical oxygen demand (COD), total nitrogen (TN) and total phosphorus (TP) were evaluated to check the quality of treated water. It was found that a suspended growth sequencing batch bioreactor (SGSBBR) achieved 97% ± 2 removal efficiency over a 4 h hydraulic retention time (HRT). For an attached growth sequencing batch bioreactor (AGSBBR) results showed 98% ± 2 removal efficiencies with polyurethane. TN and TP removal efficiency was 58.7 ± 3% and 64 ± 4.8% in SGSBBR, 53 ± 0.17% and 67 ± 2.7% in polyurethane. AGSBBR enhanced performance with AGSBBR may be due to enforced anoxic/aerobic conditions in the inner layers of biofilm formed on biocarriers which facilitate the required metabolic conditions for treating high strength wastewater. Plant growth was visibly greater in SGSBBR treated wastewater than AGSBBR because of less nutrient removal.

Sign in / Sign up

Export Citation Format

Share Document