Hedgehog-like Bi2S3 nanostructures: a novel composite soft template route to the synthesis and sensitive electrochemical immunoassay of the liver cancer biomarker

2021 ◽  
Vol 57 (14) ◽  
pp. 1766-1769
Author(s):  
Jiawen Cao ◽  
Pu Ouyang ◽  
Suhua Yu ◽  
Feng Shi ◽  
Chuanli Ren ◽  
...  

A new route was proposed to synthesize novel hedgehog-like Bi2S3nanostructure using CTAB-trimellitic acid as a composite soft template and thiourea as the sulfur source, which was used  to construct an effective electrochemical AFP immunosensor.

2011 ◽  
Vol 287-290 ◽  
pp. 96-99 ◽  
Author(s):  
Xian Biao Wang ◽  
Jin Liu ◽  
Dong Lin Zhao ◽  
Xiao Jie Song

FeS nanoparticles with uniform size have been prepared through a facile route using (sodium carboxymethyl cellulose) CMC as soft template. The nanoparticles are about 4-6 nm by observation of transmission electron microscopy (TEM). The CMC template could also stabilize the FeS nanoparticles and resist aggregation. It is important to note that the size of nanoparticles can be easily controlled by the concentration of iron and sulfur source during the synthetic process. Interestingly, the FeS nanoparticles could assemble into rod-like morphology at higher concentration. More importantly, the CMC-stabilized FeS nanoparticles exibit enhanced performance for Cr(Ⅵ) removal as compared with FeS synthesized without CMC stabilizer.


2018 ◽  
Vol 765 ◽  
pp. 115-118
Author(s):  
Thidarat Wangkham

Materials modification with surface functional group for bioactive film or sensor surface is important in many applications. A suitable surface for each system can be shown high efficiency of detection. In this work, two different surfaces via covalent binding are created on gold substrate for finding the suitable surface in medical applications. The liver cancer biomarker, alpha-fetoprotein (AFP) was detected on two surfaces; one is carboxy dextran and another is a modified polymethyl metacrylate (PMMA). The substrates were improved by physical and chemical binding for AFP antibody immobilization. Contact angle and surface Plasmon resonance (SPR) were used to study the characteristic of surfaces. The result was found that the carboxy dextran gave higher detection than PMMA. Moreover, the dextran surface was studied in real serum samples. It was shown the significantly different between positive and negative AFP serum which is preliminary results for testing in more clinical samples further.


2015 ◽  
Vol 4 ◽  
pp. 40-45 ◽  
Author(s):  
Shuaipeng Wang ◽  
Jingjing Wang ◽  
Yinfang Zhu ◽  
Jinling Yang ◽  
Fuhua Yang

2014 ◽  
Vol 6 (22) ◽  
pp. 8878-8881 ◽  
Author(s):  
C. K. Tang ◽  
A. Vaze ◽  
J. F. Rusling

Inexpensive, reusable electrochemical chips were configured as immunosensors by using a filter paper disk equipped with antibodies. Rapid detection of cancer biomarker protein prostate specific antigen (PSA) in serum was achieved with 6 pg mL−1 detection in ∼15 min.


Database ◽  
2014 ◽  
Vol 2014 (0) ◽  
pp. bau085-bau085 ◽  
Author(s):  
H.-J. Dai ◽  
J. C.-Y. Wu ◽  
W.-S. Lin ◽  
A. J. F. Reyes ◽  
M. A. C. dela Rosa ◽  
...  

2014 ◽  
Vol 35 (10) ◽  
pp. 104008 ◽  
Author(s):  
Shuaipeng Wang ◽  
Jingjing Wang ◽  
Yinfang Zhu ◽  
Jinling Yang ◽  
Fuhua Yang

2016 ◽  
Vol 8 (27) ◽  
pp. 5398-5406 ◽  
Author(s):  
Yuanyuan Wu ◽  
Peng Wei ◽  
Sumate Pengpumkiat ◽  
Emily A. Schumacher ◽  
Vincent T. Remcho

Non-toxic, fluorescent carbon nanodot labels are employed as novel ratiometric immunosensors for α-fetoprotein (AFP), a liver cancer biomarker. The assay generates a broad linear range, a low detection limit, and can be adapted to a variety of immunoassay targets.


2008 ◽  
Vol 104 (1) ◽  
pp. 136-149 ◽  
Author(s):  
Pamela A. Norton ◽  
Mary Ann Comunale ◽  
Jonathan Krakover ◽  
Lucy Rodemich ◽  
Natalie Pirog ◽  
...  

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