scholarly journals Development of label-free gold nanoparticle based rapid colorimetric assay for clinical/point-of-care screening of cervical cancer

2020 ◽  
Vol 2 (12) ◽  
pp. 5737-5745
Author(s):  
Tejaswini Appidi ◽  
Sushma V. Mudigunda ◽  
Suseela Kodandapani ◽  
Aravind Kumar Rengan
Keyword(s):  
Cervical Cancer ◽  
Gold Nanoparticles ◽  
Gold Nanoparticle ◽  
Colorimetric Assay ◽  
Point Of Care ◽  
Colorimetric Detection ◽  
Label Free ◽  
Free Gold ◽  
Clinical Point

“C-ColAur” technique for colorimetric detection of cervical cancer by in situ formation of gold nanoparticles.

Analyte-triggered autocatalytic amplification combined with gold nanoparticle probes for colorimetric detection of heavy-metal ions

2017 ◽  
Vol 53 (54) ◽  
pp. 7477-7480 ◽  
Author(s):  
Juanhua Yang ◽  
Yun Zhang ◽  
Lang Zhang ◽  
Huili Wang ◽  
Jinfang Nie ◽  
...  
Keyword(s):  
Heavy Metal ◽  
Gold Nanoparticles ◽  
Metal Ions ◽  
Gold Nanoparticle ◽  
Heavy Metal Ions ◽  
Colorimetric Detection ◽  
Detection Limits ◽  
Label Free ◽  
Nanoparticle Probes ◽  
Free Gold

This work reports a new nanosensor based on analyte-triggered autocatalytic amplification and label-free gold nanoparticles for the colorimetric detection of Hg2+, Cu2+and Ag+with detection limits less than 3 nM.

Colorimetric Detection of DNA Sequences Using an Organic Solvent to Induce the Aggregation of Label-Free Gold Nanoparticles

2013 ◽  
Vol 13 (6) ◽  
pp. 3805-3809 ◽  
Author(s):  
Huning Jia ◽  
Xiaomei Cao ◽  
Cong Fu ◽  
Jianping Wang ◽  
Zhiyao Chen ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Organic Solvent ◽  
Dna Sequences ◽  
Colorimetric Detection ◽  
Label Free ◽  
Free Gold

scholarly journals Specific pH effect for selective colorimetric assay of glutathione using anti-aggregation of label-free gold nanoparticles

RSC Advances ◽  
2017 ◽  
Vol 7 (22) ◽  
pp. 13426-13432 ◽  
Author(s):  
Jian-Fang Li ◽  
Peng-Cheng Huang ◽  
Fang-Ying Wu
Keyword(s):  
Gold Nanoparticles ◽  
Colorimetric Assay ◽  
Ph Effect ◽  
Colorimetric Method ◽  
Label Free ◽  
Free Gold

An operationally simple colorimetric method for measuring glutathione (GSH) concentration was developed using anti-aggregation of gold nanoparticles (AuNPs) in this work.

scholarly journals Label-Free Colorimetric Detection of Urine Glucose Based on Color Fading Using Smartphone Ambient-Light Sensor

Chemosensors ◽  
2020 ◽  
Vol 8 (1) ◽  
pp. 10 ◽  
Author(s):  
Wang ◽  
Guo ◽  
Hu ◽  
Liang ◽  
Li ◽  
...  
Keyword(s):  
Limit Of Detection ◽  
Colorimetric Assay ◽  
Point Of Care ◽  
Colorimetric Detection ◽  
Diabetic Patients ◽  
Ambient Light ◽  
Label Free ◽  
Urine Glucose ◽  
Light Sensor

In this work, a label-free colorimetric assay was developed for the determination of urine glucose using smartphone ambient-light sensor (ALS). Using horseradish peroxidase—hydrogen peroxide—3,3′,5,5′-tetramethylbenzidine (HRP-H2O2-TMB) colored system, quantitative H2O2 was added to samples to-be-determined for deepest color. The presence of glucose oxidase in urine led to the formation of H2O2 and the reduction of TMBred. As a result of this, the color of the urine faded and the solution changed from deep blue to light blue. We measured the illuminance of the transmitted light by a smartphone ambient light sensor, and thereby color changes were used to calculate the content of urine glucose. After method validation, this colorimetric assay was practically applied for the determination of urine samples from diabetic patients. Good linearity was obtained in the range of 0.039–10.000 mg/mL (R2 = 0.998), and a limit of detection was 0.005 mg/mL. Our method was had high accuracy, sensitivity, simplicity, rapidity, and visualization, providing a new sensor to be potentially applicable for point-of-care detection of urine glucose.

Sensitive colorimetric detection of cyromazine in cucumber samples by using label-free gold nanoparticles and polythymine

The Analyst ◽  
2015 ◽  
Vol 140 (9) ◽  
pp. 3064-3069 ◽  
Author(s):  
Jinchuan Liu ◽  
Wenhui Bai ◽  
Chao Zhu ◽  
Mengmeng Yan ◽  
Shuming Yang ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Colorimetric Detection ◽  
Colorimetric Method ◽  
Label Free ◽  
Free Gold

A sensitive colorimetric method for cyromazine detection in cucumber samples was developed by using label-free gold nanoparticles and polythymine.

A gold nanoparticle-based label free colorimetric aptasensor for adenosine deaminase detection and inhibition assay

The Analyst ◽  
2015 ◽  
Vol 140 (5) ◽  
pp. 1572-1577 ◽  
Author(s):  
Fen Cheng ◽  
Yue He ◽  
Xiao-Jing Xing ◽  
Dai-Di Tan ◽  
Yi Lin ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Adenosine Deaminase ◽  
Gold Nanoparticle ◽  
Label Free ◽  
Inhibition Assay ◽  
Free Gold ◽  
Novel Strategy ◽  
Colorimetric Aptasensor

A novel strategy for the fabrication of a colorimetric aptasensor using label free gold nanoparticles (AuNPs) is proposed. The aptasensor consists of adenosine (AD) aptamer, AD and AuNPs. The strategy has been employed for the assay of adenosine deaminase (ADA) activity.

A colorimetric approach for measuring mercuric ions with high selectivity using label-free gold nanoparticles and thiourea

2015 ◽  
Vol 7 (16) ◽  
pp. 6837-6841 ◽  
Author(s):  
Qianru Wang ◽  
Yiran Li ◽  
Min Li ◽  
Congying Wen ◽  
Rongsheng Liu ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
High Selectivity ◽  
Colorimetric Assay ◽  
Label Free ◽  
Au Nps ◽  
Free Gold ◽  
Mercuric Ions

A simple, sensitive and selective colorimetric assay was developed for detecting Hg2+ by coupling Au NPs with thiourea.

Gold nanoparticle-based exonuclease III signal amplification for highly sensitive colorimetric detection of folate receptor

Nanoscale ◽  
2014 ◽  
Vol 6 (6) ◽  
pp. 3055-3058 ◽  
Author(s):  
Xinjian Yang ◽  
Zhiqiang Gao
Keyword(s):  
Gold Nanoparticles ◽  
Small Molecule ◽  
Signal Amplification ◽  
Colorimetric Assay ◽  
Folate Receptor ◽  
Colorimetric Detection ◽  
Label Free ◽  
Exonuclease Iii ◽  
Highly Sensitive ◽  
Highly Sensitive Detection

By combining terminal protection of small molecule (folate)-capped DNA probes, exonuclease III signal amplification and gold nanoparticles, we developed a simple and label-free colorimetric assay for highly sensitive detection of folate receptor.

Colorimetric Detection of Heavy Metal Ions Using Label-Free Gold Nanoparticles and Alkanethiols

2010 ◽  
Vol 114 (39) ◽  
pp. 16329-16334 ◽  
Author(s):  
Yu-Lun Hung ◽  
Tung-Ming Hsiung ◽  
Yi-You Chen ◽  
Yu-Fen Huang ◽  
Chih-Ching Huang
Keyword(s):  
Heavy Metal ◽  
Gold Nanoparticles ◽  
Metal Ions ◽  
Heavy Metal Ions ◽  
Colorimetric Detection ◽  
Label Free ◽  
Free Gold

Nitrilotriacetate-stabilized gold nanoparticles: a novel strategy for the colorimetric detection of Cr(iii)/Cr(vi) and the mechanistic aspects

2017 ◽  
Vol 9 (19) ◽  
pp. 2805-2811 ◽  
Author(s):  
Jianyu Wei ◽  
Luming Yang ◽  
Guozong Yue ◽  
Jing Zhu ◽  
Deshun Huang ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Gold Nanoparticle ◽  
Colorimetric Assay ◽  
Colorimetric Detection ◽  
One Pot ◽  
One Pot Synthesis ◽  
Novel Strategy

Nitrilotriacetate (NTA) has been reported to behave as both a reductant and a stabilizer for gold nanoparticle (AuNP) preparation in a one-pot synthesis and colorimetric assay.

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