scholarly journals More than one way to bind to cholesterol: atypical variants of membrane-binding domain of perfringolysin O selected by ribosome display

RSC Advances ◽  
2020 ◽  
Vol 10 (63) ◽  
pp. 38678-38682
Author(s):  
Aleksandra Šakanović ◽  
Nace Kranjc ◽  
Neža Omersa ◽  
Marjetka Podobnik ◽  
Gregor Anderluh
Keyword(s):  
Amino Acid ◽  
Clostridium Perfringens ◽  
Membrane Binding ◽  
Binding Domain ◽  
Amino Acid Substitutions ◽  
Ribosome Display ◽  
Perfringolysin O

By using developed ribosomal display, we discovered variants of perfringolysin O, a pore forming toxin from bacteria Clostridium perfringens, with non-conserved amino acid substitutions at regions crucial for cholesterol recognition.

scholarly journals Biophysical studies of cytochromes B5 with amino acid substitutions in the membrane-binding domain

1992 ◽  
Vol 62 (1) ◽  
pp. 79-81 ◽  
Author(s):  
A.S. Ladokhin ◽  
V.G. Tretyachenko-Ladokhina ◽  
P.W. Holloway ◽  
L. Wang ◽  
A.W. Steggles
Keyword(s):  
Amino Acid ◽  
Membrane Binding ◽  
Binding Domain ◽  
Amino Acid Substitutions ◽  
Biophysical Studies

Amino acid substitutions in the membrane-binding domain of cytochrome b5 alter its membrane-binding properties

1993 ◽  
Vol 1153 (2) ◽  
pp. 163-169 ◽  
Author(s):  
Vera G. Tretyachenko-Ladokhina ◽  
Alexey S. Ladokhin ◽  
Liming Wang ◽  
Alan W. Steggles ◽  
Peter W. Holloway
Keyword(s):  
Amino Acid ◽  
Cytochrome B5 ◽  
Membrane Binding ◽  
Binding Domain ◽  
Amino Acid Substitutions ◽  
Binding Properties

Human androgen insensitivity due to point mutations encoding amino acid substitutions in the androgen receptor steroid-binding domain

1995 ◽  
Vol 6 (2) ◽  
pp. 152-162 ◽  
Author(s):  
Koichi Murono ◽  
Berenice B. Mendonca ◽  
Ivo J. P. Arnhold ◽  
Ana C. M. M. Rigon ◽  
Claude J. Migeon ◽  
...  
Keyword(s):  
Androgen Receptor ◽  
Amino Acid ◽  
Point Mutations ◽  
Binding Domain ◽  
Amino Acid Substitutions ◽  
Androgen Insensitivity ◽  
Steroid Binding

scholarly journals Effect of Amino Acid Substitutions in the Rad50 ATP Binding Domain on DNA Double Strand Break Repair in Yeast

2004 ◽  
Vol 280 (4) ◽  
pp. 2620-2627 ◽  
Author(s):  
Ling Chen ◽  
Kelly M. Trujillo ◽  
Stephen Van Komen ◽  
Dong Hyun Roh ◽  
Lumir Krejci ◽  
...  
Keyword(s):  
Amino Acid ◽  
Strand Break ◽  
Double Strand Break ◽  
Binding Domain ◽  
Double Strand Break Repair ◽  
Atp Binding ◽  
Amino Acid Substitutions ◽  
Dna Double Strand Break ◽  
Break Repair
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