myristic acid
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2022 ◽  
Vol 335 ◽  
pp. 00047
Author(s):  
Poespitasari Hazanah Ndaru ◽  
Siti Chuzaemi ◽  
Muhimmatu Mufidah

The purpose of this research was to determine the influence of Myristic acid and the source of condensed tannin on corn straw basedcomplete feed on nutrient content and in vitro digestibility. The method which was used in this experiment was randomized block design with four treatments and three replications. The treatment consisted of T0 complete feed (40% corn straw + 60% concentrate), T1 complete feed (40% corn straw + 60% concentrate + myristic acid 30 g/Kg DM), T2 complete feed (40% corn straw + 50% concentrate + calliandra leaf meal 10%/Kg DM and myristic acid 30 g/Kg DM), T3 complete feed (40% corn straw + 45% concentrate + calliandra leaf meal 15%/Kg DM and myristic acid 30 g/Kg DM), T4 (40% corn straw + 40% concentrate + calliandra leaf meal 20%/Kg DM and myristic acid 30 g/Kg DM). Based on the result, it could be concluded that calliandra leaf meal 15%/Kg DM + Myristic acid 30 g/Kg DM on the complete feed (T3) was the best treatment based on nutrient content and increase of dry matter digestibility, but not an effect of organic matter digestibility


Author(s):  
Felipe Andrade-Villalobos ◽  
Daniel Zúñiga-Núñez ◽  
Angelica Fierro ◽  
Denis Fuentealba

A new toluidine blue-myristic acid photosensitizer derivate (TBOMyr) was investigated as a design molecule to bind simultaneously to cucurbit[7]uril (CB[7]) and human serum albumin (HSA) with the aim of constructing...


2022 ◽  
Vol 335 ◽  
pp. 00028
Author(s):  
Siti Chuzaemi ◽  
Iftitah Nuzulia Qur’any

The study aimed to determine the effect of adding tannin and myristic acid in complete feed on nutrient content and the Profile of volatile fatty acids (VFA) in vitro. The materials used for this research were corn straw, condensed tannins, myristic acid, coffee waste, rice bran, tapioca byproduct, soybean meal, copra meal, and palm kernel meal. The method was used in this experiment was laboratory experiment with four treatments and three replications. The treatment consisted of T1 complete feed (40% corn straw + 60% concentrate (be based DM)), T2 (complete feed + condensed tannins 3%/kg DM and myristic acid 2%/kg DM), T3 (complete feed + condensed tannins 3%/kg DM and myristic acid 3%/kg DM), and T4 (complete feed + condensed tannins 3%/kg DM and myristic acid 4%/kg DM). Every treatment was repeated three times and analysed statistically using Randomized Block Design (RBD). The adding of 4% myristic acid to the complete feed (T4) gives the best results, it increased nutrition and propionic acid, but decreased acetic acid, butyric acid, total VFA and C2/C3 ratio.


2021 ◽  
Vol 1 (3) ◽  
pp. 73
Author(s):  
Mahyuni Marito Harahap ◽  
Azhari Azhari ◽  
Meriatna Meriatna ◽  
Suryati Suryati ◽  
Syamsul Bahri

AbstrakTanaman orok-orok (crotalaria juncea) adalah tanaman leguminosa yang termasuk kedalam keluarga perdu dan semak. Biji orok-orok dapat digunakan sebagai obat insomnia dan sebagai bahan baku pembuatan biodiesel karena mengandung 12,6 % minyak dengan 46,8 % asam linoleate. 4,6 % asam linolenat, 28,3 % asam oleat dan 20,3 % asam jenuh. Untuk mendapatkan minyak dari biji orok-orok yang akan digunakan sebagai bahan baku biodiesel dapat dilakukan dengan metode ekstraksi padat-cair menggunakan pelarut N-Heksan. Pada penelitian ini bahan baku yang digunakan adalah biji orok-orok dan N-Heksan. Biji orok-orok dihaluskan menggunakan blender, kemudian dimasukkan dalam labu leher tiga untuk proses ekstraksi menggunakan pelarut N-Heksan. Ekstraksi dilakukan dengan memvariasikan suhu ekstraksi dan volume pelarut dengan waktu ekstraksi 5 jam dan bahan baku sebanyak 100 gr. Setelah selesai ekstraksi larutan disaring menggunakan kertas saring. Selanjutnya dilakukan pemisahan antara minyak dan pelarut dengan proses destilasi. Pengujian yang dilakukan adalah uji densitas, yield, kadar FFA, viscositas, densitas dan uji komposisi dengan alat GC-MS. Densitas terendah dihasilkan pada suhu 500C, berat sampel 100 gr, waktu ekstraksi 5 jam dan volume pelarut sebanyak 400 ml sebesar 1 g/ml. Yield tertinggi dihasilkan pada suhu 600C, berat sampel 100 gr, volume pelarut 700 ml dan waktu ekstraksi 5 jam sebesar 35,52 %. Kadar FFA terendah dihasilkan pada suhu 500C, berat sampel 100 gr, volume pelarut 500 ml dan waktu 5 jam sebesar 1,39 %. Viscositas hasil terbaik yang didapatkan adalah pada volume 700 ml dengan waktu ekstraksi 5 jam menggunakan pelarut N-Heksan pada suhu 600c sebesar 1 cp. Dari hasil uji GC-MS diketahui bahwa minyak biji orok-orok mengandung methyl ester of undecanoic acid, 2-methylpentanoic acid, myristic acid methyl ester, methyl linolelaidate, 2-cyclopentylacetohydrazide dan 2-methylpentanoic acid. 


2021 ◽  
Vol 22 (24) ◽  
pp. 13565
Author(s):  
Kristin Oepen ◽  
Hüseyin Özbek ◽  
Anja Schüffler ◽  
Johannes C. Liermann ◽  
Eckhard Thines ◽  
...  

ATP-binding cassette (ABC) transporters are conserved in all kingdoms of life, where they transport substrates against a concentration gradient across membranes. Some ABC transporters are known to cause multidrug resistances in humans and are able to transport chemotherapeutics across cellular membranes. Similarly, BmrA, the ABC transporter of Bacillus subtilis, is involved in excretion of certain antibiotics out of bacterial cells. Screening of extract libraries isolated from fungi revealed that the C14 fatty acid myristic acid has an inhibitory effect on the BmrA ATPase as well as the transport activity. Thus, a natural membrane constituent inhibits the BmrA activity, a finding with physiological consequences as to the activity and regulation of ABC transporter activities in biological membranes.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Wuwen Feng ◽  
Juan Liu ◽  
Dandan Zhang ◽  
Yuzhu Tan ◽  
Hao Cheng ◽  
...  

AbstractIn recent decades, herbal medicines have played more and more important roles in the healthcare system in the world because of the good efficacy. However, with the increasing use of herbal medicines, the toxicity induced by herbal medicines has become a global issue. Therefore, it is needed to investigate the mechanism behind the efficacy and toxicity of herbal medicines. In this study, using Aconiti Lateralis Radix Praeparata (Fuzi) as an example, we adopted a systems pharmacology approach to investigate the mechanism of Fuzi in treating rheumatoid arthritis and in inducing cardiac toxicity and neurotoxicity. The results showed that Fuzi has 25 bioactive compounds that act holistically on 61 targets and 27 pathways to treat rheumatoid arthritis, and modulation of inflammation state is one of the main mechanisms of Fuzi. In addition, the toxicity of Fuzi is linked to 32 compounds that act on 187 targets and 4 pathways, and the targets and pathways can directly modulate the flow of Na+, Ca2+, and K+. We also found out that non-toxic compounds such as myristic acid can act on targets of toxic compounds and therefore may influence the toxicity. The results not only reveal the efficacy and toxicity mechanism of Fuzi, but also add new concept for understanding the toxicity of herbal medicines, i.e., the compounds that are not directly toxic may influence the toxicity as well.


Author(s):  
Angel Josabad Alonso‐Castro ◽  
Roberto Serrano‐Vega ◽  
Salud Pérez Gutiérrez ◽  
Mario Alberto Isiordia‐Espinoza ◽  
Cesar Rogelio Solorio‐Alvarado

2021 ◽  
Author(s):  
Chaowu Yang ◽  
Mohan Qiu ◽  
Chunlin Yu ◽  
Han Peng ◽  
Xiaoyan Song ◽  
...  

Abstract Backgroud Studies have shown that prebiotics could affect meat quality, but the underlying mechanism are poorly understood. This study aimed to investigate whether prebiotics affect chicken’s meat quality through gut microbiome and metabolome. Methods The gut content were collected from chickens fed with or without prebiotics (galactooligosaccharides or xylo-oligosaccharides) and subjected to microbiome and metabolome analyses, and chicken breast was performed transcriptome sequencing. Results The prebiotics altered proportions of microbiota in gut contents at different levels, especially microbiota in the phylum of Bacteroidetes and Firmicutes, such as genus of Alistipes, Bacteroides, and Faecalibacterium. The prebiotics also altered contents of caecal metabolites such as lysophosphatidylcholine (lysoPC), intramuscular fat and flavor compound (Benzaldehyde and myristic acid). Differentially expressed genes (DEGs) induced by prebiotics were significantly involved in regulation of lipolysis inadipocytes and adipocytokine signaling pathway. Changes in gut microbiota and metabolites were remarkably correlated such as Bacteroidetes and Firmicutes was respectively positively and negatively correlated with lysoPC. DEGs were also interacted with caecal metabolites. Conclusion These findings integrated and incorporated link among gut microbiota, metabolites and transcriptome, which proposed prebiotics may affect meat quality and flavor of chickens.


Energies ◽  
2021 ◽  
Vol 14 (21) ◽  
pp. 6860
Author(s):  
Yamuna Munusamy ◽  
John Wong Lin Onn ◽  
Mohammed Alquraish ◽  
Mohamed Kchaou ◽  
Sumathi Sethupathi

Photovoltaic (PV) panels must be equipped with a cooling system to increase their electrical output generation. Despite numerous publications on the fabrication of form-stable phase change material (FSPCM) for thermal energy storage application, studies on the usage of FSPCM for PV cooling are incredibly limited. In this work, the cooling performance of myristic acid FSPCM encapsulated with cross-linked nitrile rubber (NBR) was investigated. A fin heat sink (FHS) was employed to hold the FSPCM. The thermal performance of the FHS embedded with FSPCM (FHS-FSPCM) was preliminarily tested in an indoor setup. Results show that the FHS-FSPCM has a lower temperature distribution curve than the bare FHS, highlighting the increase in cooling capability of fabricated FSPCM. Field-testing of PV panels integrated with an FHS-FSPCM displayed that FSPCM manages to reduce the operating temperature of the panel by 4 to 15 °C and increase power output generation by 38.61%.


2021 ◽  
Vol 8 (1) ◽  
pp. 67
Author(s):  
Sri Indriati ◽  
Muhammad Yusuf ◽  
Riskayanti Riskayanti ◽  
Nur Amaliah ◽  
Mahyati Latief ◽  
...  

Safflower, were extracted using propanol solvent at different time intervals: 10, 20, and 30 min at a constant temperature of 40°C. The extracts were analyzed by GC/MS technique. The major compounds identified were tetrapentacontane, tetracontane, triacontanol, gamma sitosterol, myristic acid, linoleic acid, stearic acid, palmitic acid, oleic acid, and lauric acid. However, some levels of palmidrol, beta-amyrin, cubenol, and tocopherol were also found in safflower extracts. Most of the volatile compounds were detected between 10–30 min time of extraction. The 30 min time of extraction also showed the maximum content of polyphenols and antioxidants in safflower extracts. Thus, 30 min was suggested as the most suitable time for maximum extraction of bioactive volatiles, antioxidants, and polyphenols from Safflower using propanol solvent.


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