One-pot synthesis of acid-degradable polyphosphazene prodrugs for efficient tumor chemotherapy

2020 ◽  
Vol 8 (46) ◽  
pp. 10540-10548
Author(s):  
Na Zhou ◽  
Ning Zhang ◽  
Zhe Zhi ◽  
Xunan Jing ◽  
Daomeng Liu ◽  
...  
Keyword(s):  
Side Effects ◽  
Anticancer Drugs ◽  
Therapeutic Efficacy ◽  
Ph Sensitive ◽  
One Pot ◽  
One Pot Synthesis

In order to improve the therapeutic efficacy and reduce the side effects of anticancer drugs, pH sensitive and biodegradable polyphosphazene prodrugs were prepared.

scholarly journals One-pot synthesis of biodegradable polydopamine-doped mesoporous silica nanocomposites (PMSNs) as pH-sensitive targeting drug nanocarriers for synergistic chemo-photothermal therapy

RSC Advances ◽  
2018 ◽  
Vol 8 (65) ◽  
pp. 37433-37440 ◽  
Author(s):  
Huicong Zhang ◽  
Xuandong Wang ◽  
Peiyuan Wang ◽  
Rong Liu ◽  
Xuemei Hou ◽  
...  
Keyword(s):  
Drug Release ◽  
Mesoporous Silica ◽  
Photothermal Therapy ◽  
Ph Sensitive ◽  
Ph Responsive ◽  
One Pot ◽  
Silica Nanocomposites ◽  
One Pot Synthesis ◽  
Drug Nanocarriers

Polydopamine-doped mesoporous silica nanocomposites (PMSNs) were controllably synthesized by a one-pot approach. They were demonstrated to be good biodegradability, pH-responsive drug release and targeting synergistic chemo-photothermal therapy.

A new Vilsmeier-type reaction for one-pot synthesis of pH sensitive fluorescent cyanine dyes

Tetrahedron ◽  
2006 ◽  
Vol 62 (33) ◽  
pp. 7793-7798 ◽  
Author(s):  
Reda M. El-Shishtawy ◽  
Paulo Almeida
Keyword(s):  
Cyanine Dyes ◽  
Ph Sensitive ◽  
One Pot ◽  
Type Reaction ◽  
One Pot Synthesis

scholarly journals One-pot synthesis of reactive oxygen species (ROS)-self-immolative polyoxalate prodrug nanoparticles for hormone dependent cancer therapy with minimized side effects

2017 ◽  
Vol 8 (13) ◽  
pp. 1999-2004 ◽  
Author(s):  
Anita Höcherl ◽  
Eliézer Jäger ◽  
Alessandro Jäger ◽  
Martin Hrubý ◽  
Rafał Konefał ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Side Effects ◽  
Cancer Therapy ◽  
Reactive Oxygen ◽  
Oxygen Species ◽  
One Pot ◽  
One Pot Synthesis

One-pot synthesis of ROS-self-immolative polyoxalate prodrug NPs for cancer therapy.

One-pot synthesis of pH-sensitive poly(RGD-co-β-amino ester)s for targeted intracellular drug delivery

2014 ◽  
Vol 5 (3) ◽  
pp. 844-853 ◽  
Author(s):  
Zeng-Ying Qiao ◽  
Sheng-Lin Qiao ◽  
Gang Fan ◽  
Yun-Shan Fan ◽  
Yu Chen ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Ph Sensitive ◽  
Amino Ester ◽  
One Pot ◽  
One Pot Synthesis ◽  
Intracellular Drug Delivery

One-pot synthesis of template-free hollow anisotropic CaCO3 structures: towards inorganic shape-mimicking drug delivery systems

2020 ◽  
Vol 56 (80) ◽  
pp. 11969-11972
Author(s):  
Nikita Serov ◽  
Darina Darmoroz ◽  
Alina Lokteva ◽  
Ivan Chernyshov ◽  
Elena Koshel ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Ph Sensitive ◽  
Release Behavior ◽  
One Pot ◽  
One Pot Synthesis ◽  
Template Free

A template-free approach for the formulation of hollow bacteria-like CaCO3-based pH-sensitive drug delivery systems (DDSs) with controllable anisotropy and click-release behavior is developed to make a step towards shape-mimicking DDSs.

Magnetic liposomes for light-sensitive drug delivery and combined photothermal–chemotherapy of tumors

2019 ◽  
Vol 7 (7) ◽  
pp. 1096-1106 ◽  
Author(s):  
Song Shen ◽  
Danhuang Huang ◽  
Jin Cao ◽  
Ying Chen ◽  
Xin Zhang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Side Effects ◽  
Cancer Therapy ◽  
Anticancer Drugs ◽  
Targeted Delivery ◽  
Therapeutic Efficacy

The targeted delivery of anticancer drugs for improving the therapeutic efficacy and reducing the side effects has attracted great attention in cancer therapy.

One-pot synthesis and loading of mesoporous SiO2 nanocontainers using micellar drugs as a template

RSC Advances ◽  
2016 ◽  
Vol 6 (42) ◽  
pp. 36207-36210 ◽  
Author(s):  
O. V. Dement'eva ◽  
V. M. Rudoy
Keyword(s):  
Mesoporous Silica ◽  
Ph Sensitive ◽  
One Pot ◽  
New Approach ◽  
One Pot Synthesis ◽  
Mesoporous Sio2

A new approach is proposed for creating of pH-sensitive mesoporous silica nanocontainers with ultrahigh capacity for amphiphilic functional compounds.

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