scholarly journals A near-infrared fluorescent probe based on a hemicyanine dye with an oxazolidine switch for mitochondrial pH detection

2021 ◽  
Author(s):  
Wafa Mazi ◽  
Yunnan Yan ◽  
Yibin Zhang ◽  
Shuai Xia ◽  
Shulin Wan ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Hela Cells ◽  
Near Infrared ◽  
Hemicyanine Dye ◽  
Ph Detection

A near-infrared fluorescent probe (AH+) has been prepared by incorporating an oxazolidine switch into a near-infrared hemicyanine dye for pH detection in the mitochondria of HeLa cells.

A benzothiazole-based near-infrared fluorescent probe for sensing SO2 derivatives and viscosity in HeLa cells

2021 ◽  
Vol 251 ◽  
pp. 119457
Author(s):  
Yibing Li ◽  
Yilin Zhu ◽  
Xuzi Cai ◽  
Jimin Guo ◽  
Cuiping Yao ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Hela Cells ◽  
Near Infrared

A near‐infrared fluorescent probe based on boric acid hydrolysis for hydrogen peroxide detection and imaging in HeLa cells

Luminescence ◽  
2019 ◽  
Vol 35 (2) ◽  
pp. 208-214 ◽  
Author(s):  
Tao Wang ◽  
Xiaojun Yang ◽  
Jinxia Men ◽  
Jinpei Zhou ◽  
Huibin Zhang
Keyword(s):  
Hydrogen Peroxide ◽  
Boric Acid ◽  
Acid Hydrolysis ◽  
Fluorescent Probe ◽  
Hela Cells ◽  
Near Infrared ◽  
Hydrogen Peroxide Detection

A Ratiometric Near-Infrared Fluorescent Probe Based on a Novel Reactive Cyanine Platform for Mitochondrial pH Detection

2021 ◽  
Author(s):  
Shulin Wan ◽  
Shuai Xia ◽  
Jerry Medford ◽  
Emma Durocher ◽  
Tessa E. Steenwinkel ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Near Infrared ◽  
Ph Detection

A near-infrared reactive cyanine platform (probe A) was prepared by condensation of 9-chloro-1,2,3,4-tetrahydro-10-methyl-acridinium iodide with Fisher’s aldehyde. A near-infrared fluorescent probe (probe B) was prepared by modifying a reactive chlorine...

scholarly journals Ratiometric Near-Infrared Fluorescent Probes Based on Hemicyanine Dyes Bearing Dithioacetal and Formal Residues for pH Detection in Mitochondria

Molecules ◽  
2021 ◽  
Vol 26 (7) ◽  
pp. 2088
Author(s):  
Yunnan Yan ◽  
Yibin Zhang ◽  
Shuai Xia ◽  
Shulin Wan ◽  
Tara Vohs ◽  
...  
Keyword(s):  
Fluorescent Probes ◽  
Near Infrared ◽  
Formyl Group ◽  
Pka Values ◽  
Theoretical Methods ◽  
Hemicyanine Dye ◽  
Hemicyanine Dyes ◽  
Experimental Values ◽  
Van Der Waals Radii ◽  
Ph Detection

Ratiometric near-infrared fluorescent probes (AH+ and BH+) have been prepared for pH determination in mitochondria by attaching dithioacetal and formal residues onto a hemicyanine dye. The reactive formyl group on probe BH+ allows for retention inside mitochondria as it can react with a protein primary amine residue to form an imine under slightly basic pH 8.0. Probes AH+ and BH+ display ratiometric fluorescent responses to pH changes through the protonation and deprotonaton of a hydroxy group in hemicyanine dyes with experimentally determined pKa values of 6.85 and 6.49, respectively. Calculated pKa values from a variety of theoretical methods indicated that the SMDBONDI method of accounting for solvent and van der Waals radii plus including a water molecule located near the site of protonation produced the closest overall agreement with the experimental values at 7.33 and 6.14 for AH+ and BH+ respectively.

A novel near-infrared fluorescent probe based on isophorone for the bioassay of endogenous cysteine

2021 ◽  
Author(s):  
Hong-Bo Liu ◽  
Hai Xu ◽  
Xin Guo ◽  
Jian Xiao ◽  
Zheng-Hong Cai ◽  
...  
Keyword(s):  
Aqueous Solution ◽  
Fluorescent Probe ◽  
Near Infrared ◽  
Stokes Shift ◽  
Rapid Identification ◽  
Large Stokes Shift

A near-infrared (NIR) fluorescent probe with a large Stokes shift (143 nm) for the rapid identification of Cys over Hcy and GSH in aqueous solution was developed.

A mitochondria-targeted near-infrared fluorescent probe for imaging viscosity in living cells and a diabetic mice model

2021 ◽  
Author(s):  
Bochao Chen ◽  
Shumei Mao ◽  
Yanyan Sun ◽  
Liyuan Sun ◽  
Ning Ding ◽  
...  
Keyword(s):  
Mouse Model ◽  
Fluorescent Probe ◽  
Near Infrared ◽  
Diabetic Mouse ◽  
Living Cells ◽  
Pancreatic Tissue ◽  
Diabetic Mice ◽  
Mice Model ◽  
Viscosity Changes

A mitochondria-targeted near-infrared fluorescent probe NIR-V with 700 nm emission was designed to monitor cell viscosity changes, which was applied to detect the intracellular viscosity and imagine pancreatic tissue in diabetic mouse model.

Sign in / Sign up

Export Citation Format

Share Document