scholarly journals “Sweet tooth”-oriented SN38 prodrug delivery nanoplatform for targeted gastric cancer therapy

2021 ◽  
Vol 9 (12) ◽  
pp. 2816-2830
Author(s):  
Ning Ding ◽  
Shengjun Xu ◽  
Sheng Zheng ◽  
Qianwei Ye ◽  
Li Xu ◽  
...  

Motivated by the overexpression of GLUT1 in gastric cancer, a targeted SN38 prodrug delivery nanoplatform was constructed and exhibited potent antitumor efficiency, which brought a new insight to the design of nanomedicine against cancer.

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Fanming Kong ◽  
Yang Yao ◽  
Renfen Deng ◽  
Xiaojiang Li ◽  
Yingjie Jia

2018 ◽  
Vol 233 (12) ◽  
pp. 9261-9270 ◽  
Author(s):  
Sadegh Fattahi ◽  
Mohadeseh Kosari‐Monfared ◽  
Elham Ghadami ◽  
Monireh Golpour ◽  
Parastoo Khodadadi ◽  
...  

2020 ◽  
Vol 56 ◽  
pp. 101576 ◽  
Author(s):  
Sepehr Batooei ◽  
Azim Khajeali ◽  
Roghayeh Khodadadi ◽  
Jalil Pirayesh Islamian

2019 ◽  
Vol 36 (6) ◽  
pp. 1900015 ◽  
Author(s):  
Xiangbo Meng ◽  
Ke Wang ◽  
Lin Lv ◽  
Ye Zhao ◽  
Chen Sun ◽  
...  

2022 ◽  
pp. 307-329
Author(s):  
Priyadarshini Mohapatra ◽  
Natarajan Chandrasekaran ◽  
Amitava Mukherjee

Nanoemulsion is the major vehicle for delivering different types of drugs, nucleic acids, and imaging agents. Due to their attractive properties, it has been extensively used for diagnostics of cancer therapy and imaging. However, nanoemulsion is designed through multiple functions by modifications in surface and encapsulation of active compounds against cancer. In nanoemulsion, the surface alteration can be changed by targeting the surface charge, a targeting ligand. The core of the emulsion can be loaded with drugs, imaging agents, and contrast agents. In this chapter, the application of nanoemulsion against specifically liver and gastric cancer is explored briefly. The major focuses on the severity of cancer, multifunctional nature of respective drug-loaded nanoemulsions, how to defeat the physiological hurdles, targeted and non-targeted delivery of nanoemulsion, clinical and preclinical studies are discussed with trending examples from the review of the literature and future perspectives.


RSC Advances ◽  
2018 ◽  
Vol 8 (52) ◽  
pp. 30012-30020 ◽  
Author(s):  
Shichao Ai ◽  
Shuang Zhen ◽  
Zhijian Liu ◽  
Feng Sun ◽  
Xingchen He ◽  
...  

A nontoxic, low immunogenic and high specific drug delivery system for gastric cancer.


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