scholarly journals Switching energy dissipation pathway: in situ proton-induced transformation of AIE-active self-assemblies to boost photodynamic therapy

2021 ◽  
Author(s):  
Jie Li ◽  
Jianxing Wang ◽  
Jianyu Zhang ◽  
Xiyao Hu ◽  
Dong Wang ◽  
...  

With the morphological transformation of fluorescent self-assembled nanostructures, their functions can be varied simultaneously.

2020 ◽  
Author(s):  
Jie Li ◽  
Jianxing Wang ◽  
Jianyu Zhang ◽  
Xiyao Hu ◽  
Dong Wang ◽  
...  

<p>An aggregation-induced emission-active self-assembly was fabricated to study the functions variation in morphological transformation. The excited-state energy of this self-assembly was dissipated via radiative decay showing strong emission, and the energy dissipation pathway could switch to non-radiative decay, offering high generation efficiencies of reactive oxygen species upon <i>in situ</i> proton-induced morphological transformation.</p>


Nanoscale ◽  
2020 ◽  
Vol 12 (20) ◽  
pp. 11119-11129 ◽  
Author(s):  
Yang Liu ◽  
Xiaomin Li ◽  
Xiaoyan Niu ◽  
Licheng Yu ◽  
Weizhou Sha ◽  
...  

Focusing on the high tissue hydraulic pressure in tumors leads to the low retention effect of photosensitizers (PSs), we proposed a “PSs self-fiber forming strategy” to effectively increase PSs concentration in tumor and enhance the PDT effect.


2020 ◽  
Author(s):  
Jie Li ◽  
Jianxing Wang ◽  
Jianyu Zhang ◽  
Xiyao Hu ◽  
Dong Wang ◽  
...  

<p>An aggregation-induced emission-active self-assembly was fabricated to study the functions variation in morphological transformation. The excited-state energy of this self-assembly was dissipated via radiative decay showing strong emission, and the energy dissipation pathway could switch to non-radiative decay, offering high generation efficiencies of reactive oxygen species upon <i>in situ</i> proton-induced morphological transformation.</p>


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