Porous polyelectrolyte frameworks: synthesis, post-ionization and advanced applications

2022 ◽  
Author(s):  
Ting Zhou ◽  
Xingye Huang ◽  
Ning Ding ◽  
Zheng Lin ◽  
Ying Yao ◽  
...  

This review surveys approaches to the design and synthesis of emerging porous polyelectrolyte frameworks, and provides an overview of the recent advances in energy, environmental and biomedical fields.

2021 ◽  
Vol 9 ◽  
Author(s):  
Sijin Chen ◽  
Shuting Huang ◽  
Yan Li ◽  
Chuncai Zhou

With the advantages in biocompatibility, antimicrobial ability, and comparative facile synthesis technology, poly-L-lysine (PLL) has received considerable attention in recent years. Different arrangement forms and structures of the backbone endow lysine-based polymers with versatile applications, especially for ε-poly-L-lysine (EPL) and lysine-based dendrimer (LBD) compounds. This review summarized the advanced development of the synthesis and modification strategies of EPL and LBD, focus on the modification of bio-synthesis and artificial synthesis, respectively. Meanwhile, biomedical fields, where EPL and LBD are mainly utilized, such as agents, adjuvants, or carriers to anti-pathogen or used in tumor or gene therapies, are also introduced. With the deeper of knowledge of pharmacodynamics and pharmacokinetics of the drug system, the design and synthesis of these drugs can be further optimized. Furthermore, the performances of combination with other advanced methodologies and technologies demonstrated that challenges, such as scale production and high expenses, will not hinder the prospective future of lysine-based polymers.


Materials ◽  
2018 ◽  
Vol 11 (12) ◽  
pp. 2557 ◽  
Author(s):  
Seo Lee ◽  
Jae Kang ◽  
Dokyoung Kim

Porous silicon has been utilized within a wide spectrum of industries, as well as being used in basic research for engineering and biomedical fields. Recently, surface modification methods have been constantly coming under the spotlight, mostly in regard to maximizing its purpose of use. Within this review, we will introduce porous silicon, the experimentation preparatory methods, the properties of the surface of porous silicon, and both more conventional as well as newly developed surface modification methods that have assisted in attempting to overcome the many drawbacks we see in the existing methods. The main aim of this review is to highlight and give useful insight into improving the properties of porous silicon, and create a focused description of the surface modification methods.


Author(s):  
Rongchang Luo ◽  
Min Chen ◽  
Farong Zhou ◽  
Jiamin Zhan ◽  
Qi Deng ◽  
...  

This review summarized the recent advances made in the task-specific design and synthesis of metalloporphyrin-based porous organic polymers (POPs) and their functionalization for conversion of CO2 into cyclic carbonates.


Polymers ◽  
2018 ◽  
Vol 10 (8) ◽  
pp. 830 ◽  
Author(s):  
DaeYong Lee ◽  
N. Rejinold ◽  
Seong Jeong ◽  
Yeu-Chun Kim

Stimuli-responsive polypeptides have gained attention because desirable bioactive properties can be easily imparted to them while keeping their biocompatibility and biodegradability intact. In this review, we summarize the most recent advances in various stimuli-responsive polypeptides (pH, reduction, oxidation, glucose, adenosine triphosphate (ATP), and enzyme) over the past five years. Various synthetic strategies exploited for advanced polypeptide-based materials are introduced, and their applicability in biomedical fields is discussed. The recent polypeptides imparted with new stimuli-responsiveness and their novel chemical and physical properties are explained in this review.


2016 ◽  
Vol 53 ◽  
pp. 859-884 ◽  
Author(s):  
A.K. Pandey ◽  
V.V. Tyagi ◽  
Jeyraj A/L Selvaraj ◽  
N.A. Rahim ◽  
S.K. Tyagi

2022 ◽  
Vol 25 ◽  
pp. 24-40
Author(s):  
Emilio Mateev ◽  
Maya Georgieva ◽  
Alexander Zlatkov

With the significant increase of patients suffering from different types of cancer, it is evident that prompt measures in the development of novel and effective agents need to be taken. Pyrrole moiety has been found in various active compounds with anti-inflammatory, antiseptic, antibacterial, lipid-lowering and anticancer properties. Recent advances in the exploration of highly active and selective cytotoxic structures containing pyrrole motifs have shown promising data for future investigations. Accordingly, this review presents an overview of recent developments in the pyrrole derivatives as anticancer agents, with a main focus towards the key moieties required for the anti-tumor activities. Pyrrole molecules comprising prominent targeting capacities against microtubule polymerization, tyrosine kinases, cytochrome p450 family 1, histone deacetylase and bcl-2 proteins were reported. In addition, several mechanisms of action, such as apoptosis, cell cycle arrest, inhibiting kinases, angiogenesis, disruption of cell migration, modulation of nuclear receptor responsiveness and others were analyzed. Furthermore, in most of the discussed cases we provided synthesis schemes of the mentioned molecules. Overall, the utilization of pyrrole scaffold for the design and synthesis of novel anticancer drugs could be a promising approach for future investigations.  


2018 ◽  
Vol 47 (6) ◽  
pp. 2130-2144 ◽  
Author(s):  
Yan-Xi Tan ◽  
Fei Wang ◽  
Jian Zhang

In this review, we focus on the recent advances in metal–organic zeolites (MOZs), an important branch of metal–organic frameworks.


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