Three dimensional tracking of nanoparticles by dual-color position retrieval in double-core microstructured optical fiber

Lab on a Chip ◽  
2021 ◽  
Author(s):  
Shiqi Jiang ◽  
Ronny Förster ◽  
Adrian Lorenz ◽  
Markus Schmidt
Keyword(s):  
Light Scattering ◽  
Optical Fiber ◽  
Three Dimensional ◽  
Individual Species ◽  
3D Tracking ◽  
Elastic Light Scattering ◽  
Microstructured Optical Fiber ◽  
Dual Color ◽  
Nanoscale Level

Elastic light scattering based three-dimensional (3D) tracking of objects at the nanoscale level is essential for unlocking dynamics of individual species or interactions in fields such as biology or surface...

scholarly journals Three-dimensional spatiotemporal tracking of nano-objects diffusing in water-filled optofluidic microstructured fiber

Nanophotonics ◽  
2020 ◽  
Vol 9 (15) ◽  
pp. 4545-4554
Author(s):  
Shiqi Jiang ◽  
Ronny Förster ◽  
Malte Plidschun ◽  
Jens Kobelke ◽  
Ron Fatobene Ando ◽  
...  
Keyword(s):  
Life Science ◽  
Three Dimensional ◽  
Image Plane ◽  
Observation Time ◽  
Axial Position ◽  
3D Tracking ◽  
Elastic Light Scattering ◽  
Light Line ◽  
Gold Nanosphere ◽  
Temporal And Spatial

AbstractThree-dimensional (3D) tracking of nano-objects represents a novel pathway for understanding dynamic nanoscale processes within bioanalytics and life science. Here we demonstrate 3D tracking of diffusing 100 nm gold nanosphere within a water-filled optofluidic fiber via elastic light scattering–based position retrieval. Specifically, the correlation between intensity and position inside a region of a fiber-integrated microchannel has been used to decode the axial position from the scattered intensity, while image processing–based tracking was used in the image plane. The 3D trajectory of a diffusing gold nanosphere has been experimentally determined, while the determined diameter analysis matches expectations. Beside key advantages such as homogenous light-line illumination, low-background scattering, long observation time, large number of frames, high temporal and spatial resolution and compatibility with standard microscope, the particular properties of operating with water defines a new bioanalytical platform that is highly relevant for medical and life science applications.

QUASI-ELASTIC LIGHT SCATTERING STUDIES OF THE KINETICS OF LYSOZYME DIMERIZATION

1972 ◽  
Vol 33 (C1) ◽  
pp. C1-169-C1-169
Author(s):  
Y. YEY ◽  
T. M. SCHUSTER ◽  
D. A. YPHANTIS
Keyword(s):  
Light Scattering ◽  
Elastic Light Scattering ◽  
Kinetics Of

The light-scattering Mueller matrices for Rayleigh and Rayleigh-Gans-Debye approximation

1990 ◽  
Vol 55 (12) ◽  
pp. 2889-2897
Author(s):  
Jaroslav Holoubek
Keyword(s):  
Light Scattering ◽  
Theoretical Work ◽  
Matrix Elements ◽  
Elastic Light Scattering ◽  
Yield Information ◽  
Recent Theoretical Work ◽  
Particle Parameters ◽  
Complete Set ◽  
Single Matrix ◽  
Scattering Matrix Elements

Recent theoretical work has shown that the complete set of polarized elastic light-scattering studies should yield information about scatterer structure that has so far hardly been utilized. We present here calculations of angular dependences of light-scattering matrix elements for spheres near the Rayleigh and Rayleigh-Gans-Debye limits. The significance of single matrix elements is documented on examples that show how different matrix elements respond to changes in particle parameters. It appears that in the small-particle limit (Rg/λ < 0.1) we do not loose much information by ignoring "large particle" observables.

Defect Distribution in N-Doped and Semi-Insulating 6H-SiC Bulk Single Crystal Wafers Observed by Two- and Three-Dimensional Light Scattering Tomography

2008 ◽  
Vol 47 (7) ◽  
pp. 5576-5580 ◽  
Author(s):  
Passapong Wutimakun ◽  
Taichiro Mori ◽  
Hisashi Miyazaki ◽  
Yoichi Okamoto ◽  
Jun Morimoto ◽  
...  
Keyword(s):  
Light Scattering ◽  
Single Crystal ◽  
Three Dimensional ◽  
Bulk Single Crystal ◽  
Defect Distribution

scholarly journals Parallel, linear, and subnanometric 3D tracking of microparticles with Stereo Darkfield Interferometry

2021 ◽  
Vol 7 (6) ◽  
pp. eabe3902
Author(s):  
Martin Rieu ◽  
Thibault Vieille ◽  
Gaël Radou ◽  
Raphaël Jeanneret ◽  
Nadia Ruiz-Gutierrez ◽  
...  
Keyword(s):  
High Precision ◽  
High Throughput ◽  
Single Molecule ◽  
Particle Tracking ◽  
Focal Plane ◽  
Tracking System ◽  
Three Dimensional ◽  
3D Tracking ◽  
Single Molecule Force Spectroscopy ◽  
A New Technique

While crucial for force spectroscopists and microbiologists, three-dimensional (3D) particle tracking suffers from either poor precision, complex calibration, or the need of expensive hardware, preventing its massive adoption. We introduce a new technique, based on a simple piece of cardboard inserted in the objective focal plane, that enables simple 3D tracking of dilute microparticles while offering subnanometer frame-to-frame precision in all directions. Its linearity alleviates calibration procedures, while the interferometric pattern enhances precision. We illustrate its utility in single-molecule force spectroscopy and single-algae motility analysis. As with any technique based on back focal plane engineering, it may be directly embedded in a commercial objective, providing a means to convert any preexisting optical setup in a 3D tracking system. Thanks to its precision, its simplicity, and its versatility, we envision that the technique has the potential to enhance the spreading of high-precision and high-throughput 3D tracking.

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