Quantitative activity-activity relationship (QAAR) driven design to develop hydroxamate derivatives of pentanoic acids as selective HDAC8 inhibitors: Synthesis, biological evaluation and binding mode of interaction studies
Keyword(s):
Histone deacetylase 8 (HDAC8) has been implicated as a potential drug target of many disease including cancer. HDAC8 isoform selectivity over other class-I HDACs is a major concern now-a-days. In...
2007 ◽
Vol 6
(1)
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pp. 81-81
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2013 ◽
Vol 19
(14)
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pp. 2637-2648
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2019 ◽
Vol 19
(15)
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pp. 1189-1195
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2019 ◽
Vol 20
(3)
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pp. 292-301
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2011 ◽
Vol 8
(4)
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pp. 363-370
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