A novel bifunctional chemosensor for bioimaging in living cells with highly sensitive colorimetric and fluorescent detection of CN- and Al3+

2022 ◽  
Author(s):  
luo wentao ◽  
Zhiyang Yuwen ◽  
Hui Li ◽  
Shouzhi Pu
Keyword(s):  
Living Cells ◽  
Fluorescent Chemosensor ◽  
Fluorescent Detection ◽  
Channel Response ◽  
Dual Channel ◽  
Highly Sensitive

A novel colorimetric/fluorescent chemosensor (1o) was designed and synthesized for the detection of CN- and Al3+. 1o exhibited a selective dual channel response to CN-, while it showed fluorescence changes...

A Novel Highly Sensitive Dual-channel Chemical Sensor for Sequential Recognition of Cu2+ and CN- in Aqueous Media and its Bioimaging Applications on Living Cells

2021 ◽  
Author(s):  
Yong-Qiang Xie ◽  
You-Ming Zhang ◽  
Zhao-Hui Li ◽  
Qi Xiao-Ni ◽  
Hong Yao ◽  
...  
Keyword(s):  
Chemical Sensor ◽  
Aqueous Media ◽  
Living Cells ◽  
Chemical Probe ◽  
Dual Channel ◽  
Highly Sensitive ◽  
Sequential Recognition

A simple and unique dual-channel chemical probe (DH) was designed and synthesized, which not only realized sequential recognition of Cu2+ and CN− by colorimetric and fluorometric methods, but also realized...

Triphenylphosphine-assisted highly sensitive fluorescent chemosensor for ratiometric detection of palladium in solution and living cells

RSC Advances ◽  
2015 ◽  
Vol 5 (118) ◽  
pp. 97121-97126 ◽  
Author(s):  
Hailiang Nie ◽  
Junming Geng ◽  
Jing Jing ◽  
Yamin Li ◽  
Wen Yang ◽  
...  
Keyword(s):  
Living Cells ◽  
Fluorescent Chemosensor ◽  
Highly Sensitive ◽  
Ratiometric Detection

A triphenylphosphine-assisted highly sensitive fluorescent chemosensor for ratiometric detection of palladium in solution and living cells was developed.

A near-infrared Nile red fluorescent probe for the discrimination of biothiols by dual-channel response and its bioimaging applications in living cells and animals

The Analyst ◽  
2019 ◽  
Vol 144 (11) ◽  
pp. 3676-3684 ◽  
Author(s):  
Jin-Shuai Lan ◽  
Rui-Feng Zeng ◽  
Yun Liu ◽  
Yan-Wei Xiang ◽  
Xiao-yi Jiang ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Near Infrared ◽  
Nile Red ◽  
Living Cells ◽  
Channel Response ◽  
Dual Channel ◽  
Physiological Processes

Biothiols, including cysteine (Cys), homocysteine (Hcy), glutathione (GSH) and H2S, play important roles in human physiological processes.

A novel colorimetric/fluorescence dual-channel sensor based on NBD for the rapid and highly sensitive detection of cysteine and homocysteine in living cells

2016 ◽  
Vol 8 (11) ◽  
pp. 2420-2426 ◽  
Author(s):  
Youming Shen ◽  
Xiangyang Zhang ◽  
Youyu Zhang ◽  
Chunxiang Zhang ◽  
Junling Jin ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Optical Sensing ◽  
Living Cells ◽  
Sensitive Detection ◽  
Turn On ◽  
Dual Channel ◽  
Highly Sensitive ◽  
Highly Sensitive Detection

A novel and simple turn-on fluorescent probe bearing NBD and benzaldehyde fragments for the rapid optical sensing of biothiols has been designed and synthesized.

scholarly journals A Novel Coumarin-Based Fluorescent Probe With Aggregation Induced Emission for Detecting Cn− and Its Applications in Bioimaging

2021 ◽  
Author(s):  
Sha Deng ◽  
Qiao Lei ◽  
Junzhe Cai ◽  
Yuliang Jiang ◽  
Jian Shen
Keyword(s):  
Optical Properties ◽  
Excited State ◽  
High Selectivity ◽  
High Sensitivity ◽  
Intramolecular Proton Transfer ◽  
Living Cells ◽  
Aggregation Induced Emission ◽  
Channel Response ◽  
Dual Channel ◽  
Low Toxicity

Abstract Although cyanogen ion (CN-) plays important role in industry which also bring acute environmental pollution. More serious, trace CN- enters the human body can cause serious consequences and even death. Therefore, it is of great significance to detect trace CN- with high sensitivity. Herein, a novel aggregation-induced emission (AIE) probe C-BH was synthesized based on coumarin matrix. Probe C-BH showed high selectivity and sensitivity toward CN- by dual channel response due to the excited state intramolecular proton transfer (ESIPT). The low detection limit was calculated to be 0.05 µM. Moreover, probe C-BH was successfully used for imaging CN- in living cells and zebrafish due to its low toxicity and excellent optical properties.

Highly Sensitive and Selective Colorimetric and Off−On Fluorescent Chemosensor for Cu2+in Aqueous Solution and Living Cells

2009 ◽  
Vol 81 (16) ◽  
pp. 7022-7030 ◽  
Author(s):  
Yan Zhao ◽  
Xiao-Bing Zhang ◽  
Zhi-Xiang Han ◽  
Li Qiao ◽  
Chun-Yan Li ◽  
...  
Keyword(s):  
Aqueous Solution ◽  
Living Cells ◽  
Fluorescent Chemosensor ◽  
Highly Sensitive

Fluorescence ratio imaging of dynamic intracellular ionic signals

1988 ◽  
Vol 46 ◽  
pp. 42-43
Author(s):  
R. Y. Tsien ◽  
A. Minta ◽  
M. Poenie ◽  
J.P.Y. Kao ◽  
A. Harootunian
Keyword(s):  
Binding Sites ◽  
Living Cells ◽  
Molecular Engineering ◽  
Ph Indicators ◽  
Highly Sensitive ◽  
Fluorescence Ratio Imaging ◽  
Ratio Imaging ◽  
Technical Advances ◽  
Indicator Dyes ◽  
Fluorescein Dyes

Recent technical advances now enable the continuous imaging of important ionic signals inside individual living cells with micron spatial resolution and subsecond time resolution. This methodology relies on the molecular engineering of indicator dyes whose fluorescence is strong and highly sensitive to ions such as Ca2+, H+, or Na+, or Mg2+. The Ca2+ indicators, exemplified by fura-2 and indo-1, derive their high affinity (Kd near 200 nM) and selectivity for Ca2+ to a versatile tetracarboxylate binding site3 modeled on and isosteric with the well known chelator EGTA. The most commonly used pH indicators are fluorescein dyes (such as BCECF) modified to adjust their pKa's and improve their retention inside cells. Na+ indicators are crown ethers with cavity sizes chosen to select Na+ over K+: Mg2+ indicators use tricarboxylate binding sites truncated from those of the Ca2+ chelators, resulting in a more compact arrangement of carboxylates to suit the smaller ion.

scholarly journals Anchoring zinc-doped carbon dots on a paper-based chip for highly sensitive fluorescence detection of copper ions

The Analyst ◽  
2021 ◽  
Vol 146 (20) ◽  
pp. 6297-6305
Author(s):  
Qinglan Miao ◽  
Ji Qi ◽  
Yuanyuan Li ◽  
Xinxia Fan ◽  
Dongmei Deng ◽  
...  
Keyword(s):  
Fluorescence Detection ◽  
Carbon Dots ◽  
Active Sites ◽  
Copper Ions ◽  
Fluorescent Detection ◽  
Zn Doping ◽  
Highly Sensitive ◽  
Doped Carbon Dots

A novel paper-based chip that anchored zinc-doped carbon dots was constructed for sensitive and stable fluorescent detection of Cu2+. Zn doping increased the active sites for simplifying the modification of carbon dots.

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