Recent advances in nanotechnology-based COVID-19 vaccines and therapeutic antibodies

Nanoscale ◽  
2022 ◽  
Author(s):  
Lanying Du ◽  
Yang Yang ◽  
Xiujuan Zhang ◽  
Fang Li
Keyword(s):  
Viral Agent ◽  
Therapeutic Antibodies ◽  
Recent Advances ◽  
Global Pandemic

COVID-19 has caused a global pandemic and millions of deaths. It is imperative to develop effective countermeasures against the causative viral agent, SARS-CoV-2 and its many variants. Vaccines and therapeutic...

Combating the pandemic with a potential cure: A thermostable mRNA vaccine emerges as a promising candidate against COVID-19

2020 ◽  
Vol 2 (9) ◽  
pp. 20-24
Author(s):  
Shripriya Singh ◽  
Keyword(s):  
Promising Candidate ◽  
Vaccine Candidates ◽  
Recent Advances ◽  
Global Pandemic

The ongoing global pandemic caused by the deadly SARS-CoV-2 (COVID-19) has initiated worldwide efforts to develop effective vaccines against the virus. Many promising strategies have been considered in developing vaccines. Among the various vaccine candidates, mRNA vaccine has emerged as a leading contender to contain COVID-19. We describe here some of the recent advances in thermostable mRNA vaccine and discuss its potential to neutralize the virus.

scholarly journals Blueprint for a Pop-up SARS-CoV-2 Testing Lab

2020 ◽  
Author(s):  
◽  
Dirk Hockemeyer ◽  
Fyodor Urnov ◽  
Ralph Green ◽  
Jennifer A. Doudna
Keyword(s):  
Infectious Disease ◽  
Clinical Laboratory ◽  
Transmission Rate ◽  
Clinical Sample ◽  
Viral Agent ◽  
The Novel ◽  
Bay Area ◽  
Global Pandemic ◽  
The Us ◽  
Effective Public Health

AbstractThe appearance and spread of the novel severe acute respiratory syndrome coronavirus (SARS-CoV-2) led to the official declaration of a global pandemic, with states in the US implementing shelter-in-place orders at an unprecedented scale. SARS-CoV-2 has a robust person-to-person transmission rate and an asymptomatic period of two weeks or more, leading to widespread infection that has overwhelmed healthcare infrastructures around the globe. Effective public health measures require extensive, accurate, and rapid testing to determine infection rates. Here we describe the strategy we used to establish a CLIA-licensed clinical laboratory to perform a validated Laboratory-Developed Test (LDT) for SARS-CoV-2 in Berkeley, California and the surrounding Bay Area community. Our procedures for implementing the technical, regulatory, and data management workstreams necessary for clinical sample processing provide a roadmap to aid others in setting up similar testing centers.Note on Nomenclaturein accordance with established virology and infectious disease nomenclature, throughout this document we use “SARS-CoV-2” to refer to the viral agent causing infection and “COVID-19” to refer to the human infectious disease caused by that viral agent.

scholarly journals Advances in treatment of COVID-19

2020 ◽  
Vol 1 ◽  
pp. 1
Author(s):  
Qi Wu ◽  
Yong Xu ◽  
Wen-Pan Peng ◽  
Fan-Chao Feng ◽  
Zhi-Chao Wang ◽  
...  
Keyword(s):  
Infectious Disease ◽  
Severe Acute Respiratory Syndrome ◽  
Disease Control ◽  
Human Health ◽  
The Novel ◽  
Recent Advances ◽  
Global Pandemic ◽  
Acute Infectious Disease ◽  
Novel Coronavirus

The novel coronavirus pneumonia is an acute infectious disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The global pandemic of this novel coronavirus pneumonia has greatly threatened human health and brought enormous economy losses. By the end of May 20, 2020, the pandemic of this disease had caused more than 2.70 million infections and more than 320 thousand deaths. This paper reviewed the recent advances in the treatment of the novel coronavirus pneumonia to provide basic references for disease control.

Recent Advances in High Dispersion Spectroscopy of Globular Cluster Stars

1988 ◽  
Vol 132 ◽  
pp. 525-530
Author(s):  
Raffaele G. Gratton
Keyword(s):  
Globular Cluster ◽  
Globular Clusters ◽  
High Dispersion ◽  
Photographic Material ◽  
Recent Advances ◽  
Metal Abundances ◽  
Ccd Detectors ◽  
Major Progress

The use CCD detectors has allowed a major progress in abundance derivations for globular cluster stars in the last years. Abundances deduced from high dispersion spectra now correlates well with other abundance indicators. I discuss some problems concerning the derivation of accurate metal abundances for globular clusters using high dispersion spectra from both the old photographic and the most recent CCD data. The discrepant low abundances found by Cohen (1980), from photographic material for M71 giants, are found to be due to the use of too high microturbulences.

Chelation-assisted transition metal-catalysed C–H chalcogenylations

2020 ◽  
Vol 7 (8) ◽  
pp. 1022-1060 ◽  
Author(s):  
Wenbo Ma ◽  
Nikolaos Kaplaneris ◽  
Xinyue Fang ◽  
Linghui Gu ◽  
Ruhuai Mei ◽  
...  
Keyword(s):  
Transition Metal ◽  
Recent Advances ◽  
Site Selectivity ◽  
Transition Metal Catalyzed ◽  
Metal Catalyzed

This review summarizes recent advances in C–S and C–Se formations via transition metal-catalyzed C–H functionalization utilizing directing groups to control the site-selectivity.

Nucleosome dynamics

2006 ◽  
Vol 73 ◽  
pp. 109-119 ◽  
Author(s):  
Chris Stockdale ◽  
Michael Bruno ◽  
Helder Ferreira ◽  
Elisa Garcia-Wilson ◽  
Nicola Wiechens ◽  
...  
Keyword(s):  
High Resolution ◽  
Chromatin Structure ◽  
Current Knowledge ◽  
Dynamic Properties ◽  
Structure And Dynamics ◽  
Nucleosome Dynamics ◽  
Sharp Focus ◽  
Recent Advances ◽  
Insight Into ◽  
Chromatin Structure And Dynamics

In the 30 years since the discovery of the nucleosome, our picture of it has come into sharp focus. The recent high-resolution structures have provided a wealth of insight into the function of the nucleosome, but they are inherently static. Our current knowledge of how nucleosomes can be reconfigured dynamically is at a much earlier stage. Here, recent advances in the understanding of chromatin structure and dynamics are highlighted. The ways in which different modes of nucleosome reconfiguration are likely to influence each other are discussed, and some of the factors likely to regulate the dynamic properties of nucleosomes are considered.

Recent Advances in the Treatment of Pulmonary Tuberculosis

1950 ◽  
Vol 34 (5) ◽  
pp. 1363-1380
Author(s):  
Theodore L. Badger ◽  
William E. Patton
Keyword(s):  
Pulmonary Tuberculosis ◽  
Recent Advances

Recent Advances in Thyroid Imaging

1990 ◽  
Vol 23 (2) ◽  
pp. 251-270
Author(s):  
Martin P. Sandler, MD ◽  
James A. Patton ◽  
Robert H. Ossoff
Keyword(s):  
Thyroid Imaging ◽  
Recent Advances
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