Asymmetric small organic molecule-based NIR-II fluorophores for high performance tumor phototheranostics

2021 ◽  
Author(s):  
Qi Wang ◽  
Xinrui Niu ◽  
Lingqiang Yang ◽  
Jia-Wei Liu ◽  
Jing Wang ◽  
...  
Keyword(s):  
Optical Properties ◽  
Small Molecules ◽  
High Purity ◽  
High Performance ◽  
Organic Molecule ◽  
Organic Molecules ◽  
Great Promise ◽  
Small Organic Molecules ◽  
Small Organic Molecule ◽  
Chemical Structures

Small organic molecules hold great promise for phototheranostics due to their well-defined chemical structures and optical properties, excellent biodegradation and biocompatibility, high purity, and outstanding repeatability. Nevertheless, many small molecules...

The effect of solvation and temperature on the adsorption of small organic molecules on calcite

2018 ◽  
Vol 20 (10) ◽  
pp. 7140-7147 ◽  
Author(s):  
A. Budi ◽  
S. L. S. Stipp ◽  
M. P. Andersson
Keyword(s):  
Organic Molecule ◽  
Organic Molecules ◽  
Multicomponent Mixture ◽  
Nonzero Temperature ◽  
Small Organic Molecules ◽  
Small Organic Molecule ◽  
Molecule Adsorption

The effect of multicomponent mixture on small organic molecule adsorption on calcite at nonzero temperature was investigated.

scholarly journals Small organic molecules with tailored structures: initiators in the transition-metal-free C–H arylation of unactivated arenes

RSC Advances ◽  
2020 ◽  
Vol 10 (25) ◽  
pp. 14500-14509 ◽  
Author(s):  
Zhenghui Liu ◽  
Peng Wang ◽  
Yu Chen ◽  
Zhenzhong Yan ◽  
Suqing Chen ◽  
...  
Keyword(s):  
Transition Metal ◽  
Organic Molecule ◽  
Organic Molecules ◽  
Efficient Synthesis ◽  
Small Organic Molecules ◽  
Small Organic Molecule ◽  
Metal Free ◽  
Aryl Iodides

A small organic molecule was tailored for the efficient synthesis of biphenyl and its derivatives from aryl iodides.

scholarly journals Correlations between retention volume and molecular size parameters in gel permeation chromatography of small molecules

1975 ◽  
Vol 28 (1) ◽  
pp. 189 ◽  
Author(s):  
RA Shanks
Keyword(s):  
Molecular Weight ◽  
Small Molecules ◽  
Organic Molecules ◽  
Retention Volume ◽  
Molecular Size ◽  
Gel Permeation Chromatography ◽  
Molar Volumes ◽  
Small Organic Molecules ◽  
Molecular Dimension ◽  
Gel Permeation

Gel permeation columns of Bio Beads S-X8 have been used to provide separation of oligomers and other small organic molecules. Results show successful separations up to molecular weight c. 600. The retention times of compounds have been correlated with the largest molecular dimension of the molecules and also with molar volumes.

Molecular evolution pathways during nucleation of small organic molecules: solute-rich pre-nucleation species enable control over the nucleation process

2020 ◽  
Vol 22 (33) ◽  
pp. 18663-18671
Author(s):  
Shuyi Zong ◽  
Jingkang Wang ◽  
Xin Huang ◽  
Ting Wang ◽  
Qi Liu ◽  
...  
Keyword(s):  
Molecular Evolution ◽  
Small Molecules ◽  
Organic Molecules ◽  
Nucleation Process ◽  
Small Organic Molecules

The pre-nucleation clusters played a key role in the process of crystallization of organic small molecules, indicating that the dynamics of nucleation could be regulated by changing the structure and size of the pre-nucleation clusters.

Theoretical study of phosphorene multilayers: optical properties and small organic molecule physisorption

2017 ◽  
Vol 53 (7) ◽  
pp. 5103-5113 ◽  
Author(s):  
Diego A. Ospina ◽  
Carlos A. Duque ◽  
Miguel E. Mora-Ramos ◽  
Julian D. Correa
Keyword(s):  
Optical Properties ◽  
Organic Molecule ◽  
Theoretical Study ◽  
Small Organic Molecule

Carbon Nanostructures Produced by Liquid Phase Exfoliation of Graphite in the Presence of Small Organic Molecules

2016 ◽  
Vol 3 (1) ◽  
Author(s):  
Jesús I. Tapia ◽  
Mildred Quintana
Keyword(s):  
Liquid Phase ◽  
Small Molecules ◽  
Carbon Nanostructures ◽  
Organic Molecules ◽  
Chemical Nature ◽  
Spectroscopy Analysis ◽  
Small Organic Molecules ◽  
Transmission Electron ◽  
Secondary Reactions ◽  
Carbon Nanoscrolls

AbstractWe report on the formation of different carbon nanostructures by ultrasonication of graphite in DMF upon the addition of 3 different small molecules: ferrocene carboxylic acid, dimethylamino methyl-ferrocene, and benzyl aldehyde. Our results confirm that acoustic cavitation in organic solvents generates free radicals which enable or are involved in secondary reactions. During the ultrasonication process, the addition of small molecules induces the formation of different carbon nanostructures mainly depending on the chemical nature of the molecule, as observed by transmission electron microscopy (TEM). Raman spectroscopy analysis confirms that small molecules act as radical scavengers reducing the damage caused by cavitation to graphene sheets producing long nanoribbons, squared sheets, or carbon nanoscrolls. Importantly, this strategy allows the production of different carbon nanostructures in liquid-phase making them readily available for their chemical functionalization or for their incorporation into hybrids materials enabling the development of new advanced biological applications.

Fluorescent Carbon Dots and their Applications in Sensing of Small Organic Molecules

2021 ◽  
Vol 17 ◽  
Author(s):  
Sakib Hussain Laghari ◽  
Najma Memon ◽  
Muhammad Yar Khuhawer ◽  
Taj Muhammad Jahangir
Keyword(s):  
Small Molecules ◽  
Fluorescent Probes ◽  
Carbon Dots ◽  
Organic Molecules ◽  
Fluorescent Properties ◽  
Small Organic Molecules ◽  
Uv Visible ◽  
Size Of Particles ◽  
Fluorescent Carbon Dots ◽  
Fluorescent Carbon

Background: Fluorescence-based sensing is considered highly sensitive and fluorescent probes with improved properties are always desired. Fluorescent carbon dots (CDs) are newly emerging quasi-spherical nanoparticles of less than 10 nm in size and belong to the carbon nano-material’s family. CDs have great potential as fluorescent probes and currently are under open deliberation by the researchers due to their striking properties such as low environmental hazard, high selectivity, greater sensitivity, good biocompatibility, tunable fluorescent properties and excitation dependent multicolor emission behavior. Introduction: This review demonstrates various available methods for fabrication of fluorescent CDs, capping of CDs and characterization with various techniques including UV-visible, FT-IR, and TEM. Analytical applications using CDs for the sensing of small organic molecules, specifically nitroaromatic compounds in the environmental samples are complied. Methods: The review covers literature related to synthesis and characterization of carbon dots. It includes around 171 research articles in this field. Results: Carbon dots can be synthesized using numerous routes. In all cases CDs possess spectral properties with little variation in wavelength maxima. Optical properties of CDs can be tuned by compositing these with metallic quantum dots or by modifying their surface with desired functionalities. HR-TEM is needed to see the morphology and size of particles whereas UV-Visible and FTIR are indispensable tools for this kind of research. These particles are successfully applied to sense small molecules in some matrices. Conclusion: Carbon dots are bright stars in fluorescent sensing of small molecules. However, more research is needed to determine small organic molecules in diversified areas of analysis.

OLIGOSACCHARIDE FUNCTIONALIZED NANOFIBROUS MEMBRANE

2006 ◽  
Vol 05 (01) ◽  
pp. 1-11 ◽  
Author(s):  
S. KAUR ◽  
M. KOTAKI ◽  
Z. MA ◽  
R. GOPAL ◽  
S. RAMAKRISHNA ◽  
...  
Keyword(s):  
Organic Molecule ◽  
Organic Waste ◽  
Organic Molecules ◽  
Waste Treatment ◽  
Nanofibrous Membrane ◽  
Selective Agent ◽  
Small Organic Molecules ◽  
Potential Applications ◽  
Nanofibrous Membranes ◽  
Organic Waste Treatment

An attempt was made to incorporate β-Cyclodextrin (β-CD) onto the surface of the nanofiber to target potential applications in organic waste treatment. Phenylcarbomylated and azido phenylcarbomylated β-CD were successfully blended with poly(methyl methacrylate) (PMMA) and electrospun into nanofibrous membrane respectively with an approximate diameter of 900 nm. The presence of this selective agent on the surface of the nanofibers was confirmed by ATR-FTIR and XPS. To determine the functionalized membranes ability to capture small organic molecules, a solution containing phenolphthalein (PHP), a small organic molecule, was used. The results obtained showed that the functionalized nanofibrous membranes were able to effectively capture the PHP molecules. Thus the developed β-CD functionalized nanofibrous membranes may have the potential to capture similar small organic molecules in organic waste.

Small Organic Molecules for Electrically Re-writable Non-volatile Polymer Memory Devices

2010 ◽  
Vol 1250 ◽  
Author(s):  
Iulia Salaoru ◽  
Shashi Paul
Keyword(s):  
Small Molecules ◽  
Polymer Matrix ◽  
Organic Molecules ◽  
Electrical Conductance ◽  
Metal Structure ◽  
Organic Polymer ◽  
Memory Devices ◽  
Electrical Behaviour ◽  
Small Organic Molecules ◽  
Polymer Memory

AbstractThe usage of organic materials in the manufacture of electronic polymer memory devices is on the rise. Polymer memory devices are fabricated by depositing a blend (an admixture of organic polymer, small molecules and nanoparticles) between two metal electrodes. The primary aim is to produce devices that exhibit two distinct electrical conductance states when a voltage is applied. These two states can be viewed as the realisation of non-volatile memory. This is an interesting development; however, there are a number of theories that have been proposed to explain the observed electrical behaviour. We have proposed a model that is based on electric dipole formation in the polymer matrix. Here, we investigate further the proposed model by deliberately creating electric dipoles in a polymer matrix using electron donors (8-Hydroxyquinoline, Tetrathiafulvalene and Bis(ethylenedithio)tetrathiafulvalene) and electron acceptors (7,7,8,8-Tetracyanoquinodimethane, Tetracyanoethylene and Fullerene) small molecules.Two types of structures were investigated (i) a metal/blend of polymer and small molecules/metal (MOM), device and (ii) a metal/insulator/blend of small molecules and polymer/semiconductor (MIS) architecture. A blend of polymer and small organic molecules was prepared in methanol and spin-coated onto a glass substrate marked with thin aluminium (Al) tracks; a top Al contact was then evaporated onto the blend after drying - this resulted in a metal-organic-metal structure. The MIS structures consisted of an ohmic bottom Al contact, p-type Si, a polymer blend (two small organic molecules and insulating polymer), followed by polyvinyl acetate and finally a top, circular Al electrode. In-depth FTIR studies were carried out to understand the observed electrical behaviour. An electrical analysis of these structures was performed using an HP4140B picoammeter and an HP 4192A impedance analyser at a frequency of 1 MHz.

scholarly journals Desorption/ionization on silicon for small molecules:a promising alternative to MALDI TOF.

2003 ◽  
Vol 50 (3) ◽  
pp. 783-787 ◽  
Author(s):  
Agnieszka Kraj ◽  
Tomasz Dylag ◽  
Anna Gorecka-Drzazga ◽  
Sylwester Bargiel ◽  
Jan Dziubanand ◽  
...  
Keyword(s):  
Porous Silicon ◽  
Small Molecules ◽  
Molecular Mass ◽  
Organic Molecules ◽  
Mass Region ◽  
Promising Alternative ◽  
Small Organic Molecules ◽  
Desorption Ionization ◽  
Maldi Tof ◽  
Detection And Identification

A method has been developed for laser desorption/ionization of catecholamines from porous silicon. This methodology is particularly attractive for analysis of small molecules. MALDI TOF mass spectrometry, although a very sensitive technique, utilizes matrices that need to be mixed with the sample prior to their analysis. Each matrix produces its own background, particularly in the low-molecular mass region. Therefore, detection and identification of molecules below 400 Da can be difficult. Desorption/ionization of samples deposited on porous silicon does not require addition of a matrix, thus, spectra in the low-molecular mass region can be clearly readable. Here, we describe a method for the analysis of catecholamines. While MALDI TOF is superior for proteomics/peptidomics, desorption/ionization from porous silicon can extend the operating range of a mass spectrometer for studies on metabolomics (small organic molecules and their metabolites, such as chemical neurotransmitters, prostaglandins, steroids, etc.).

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