scholarly journals Towards practical and sustainable SERS: A review of recent developments in the construction of multifunctional enhancing substrates

2021 ◽  
Author(s):  
Chunchun Li ◽  
Yiming Huang ◽  
Xinyuan Li ◽  
Yingrui Zhang ◽  
Qinglu Chen ◽  
...  
Keyword(s):  
Single Molecule ◽  
Chemical Species ◽  
Surface Enhanced Raman Spectroscopy ◽  
Quantitative Detection ◽  
Analytical Technique ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Recent Developments ◽  
Molecular Specificity ◽  
Powerful Analytical Technique

Surface-enhanced Raman spectroscopy (SERS) is a powerful analytical technique, which allows quantitative detection of chemical species with molecular specificity and single-molecule sensitivity. These useful properties can be further combined with...

scholarly journals Filter paper based SERS substrate for the direct detection of analytes in complex matrices

The Analyst ◽  
2021 ◽  
Author(s):  
Harmke Susanna Siebe ◽  
Qinglu Chen ◽  
Xinyuan Li ◽  
Yikai Xu ◽  
Wesley Browne ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Chemical Analysis ◽  
Direct Detection ◽  
High Sensitivity ◽  
Surface Enhanced Raman Spectroscopy ◽  
Sers Substrate ◽  
Analytical Technique ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Molecular Specificity

Surface-enhanced Raman spectroscopy (SERS) is an emerging analytical technique for chemical analysis, due to its combination of short measurement time, high sensitivity and molecular specificity. However, the application of SERS...

Multivariate Analysis Aided Surface-Enhanced Raman Spectroscopy (MVA-SERS) Multiplex Quantitative Detection of Trace Fentanyl in Illicit Drug Mixtures Using a Handheld Raman Spectrometer

2021 ◽  
pp. 000370282110329
Author(s):  
Ling Wang ◽  
Mario O. Vendrell-Dones ◽  
Chiara Deriu ◽  
Sevde Doğruer ◽  
Peter de B. Harrington ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Principal Component ◽  
Surface Enhanced Raman Spectroscopy ◽  
Quantitative Detection ◽  
Least Squares Regression ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Sers Detection ◽  
Current Screening

Recently there has been upsurge in reports that illicit seizures of cocaine and heroin have been adulterated with fentanyl. Surface-enhanced Raman spectroscopy (SERS) provides a useful alternative to current screening procedures that permits detection of trace levels of fentanyl in mixtures. Samples are solubilized and allowed to interact with aggregated colloidal nanostars to produce a rapid and sensitive assay. In this study, we present the quantitative determination of fentanyl in heroin and cocaine using SERS, using a point-and-shoot handheld Raman system. Our protocol is optimized to detect pure fentanyl down to 0.20 ± 0.06 ng/mL and can also distinguish pure cocaine and heroin at ng/mL levels. Multiplex analysis of mixtures is enabled by combining SERS detection with principal component analysis and super partial least squares regression discriminate analysis (SPLS-DA), which allow for the determination of fentanyl as low as 0.05% in simulated seized heroin and 0.10% in simulated seized cocaine samples.

Engineering nanostructures for single-molecule surface-enhanced Raman spectroscopy

2004 ◽  
Author(s):  
Martin Moskovits ◽  
Dae-Hong Jeong ◽  
Tsachi Livneh ◽  
Yiying Wu ◽  
Galen D. Stucky
Keyword(s):  
Raman Spectroscopy ◽  
Single Molecule ◽  
Surface Enhanced Raman Spectroscopy ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Molecule Surface

scholarly journals Surface-enhanced Raman spectroscopy: benefits, trade-offs and future developments

2020 ◽  
Vol 11 (18) ◽  
pp. 4563-4577 ◽  
Author(s):  
Ana Isabel Pérez-Jiménez ◽  
Danya Lyu ◽  
Zhixuan Lu ◽  
Guokun Liu ◽  
Bin Ren
Keyword(s):  
Raman Spectroscopy ◽  
Single Molecule ◽  
Surface Enhanced Raman Spectroscopy ◽  
Direct Identification ◽  
Molecular Fingerprints ◽  
Single Molecule Level ◽  
Trade Offs ◽  
Target Analytes ◽  
Surface Enhanced ◽  
Surface Enhanced Raman

Surface-enhanced Raman spectroscopy (SERS) is a vibrational spectroscopy technique with sensitivity down to the single molecule level that provides fine molecular fingerprints, allowing for direct identification of target analytes.

scholarly journals Revisiting semicontinuous silver films as surface-enhanced Raman spectroscopy substrates

2019 ◽  
Vol 10 ◽  
pp. 1048-1055 ◽  
Author(s):  
Malwina Liszewska ◽  
Bogusław Budner ◽  
Małgorzata Norek ◽  
Bartłomiej J Jankiewicz ◽  
Piotr Nyga
Keyword(s):  
Raman Spectroscopy ◽  
Percolation Threshold ◽  
Physical Vapor Deposition ◽  
Surface Enhanced Raman Spectroscopy ◽  
Silver Films ◽  
Analytical Technique ◽  
Detection And Identification ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
The Many

Surface-enhanced Raman spectroscopy (SERS) is a very promising analytical technique for the detection and identification of trace amounts of analytes. Among the many substrates used in SERS of great interest are nanostructures fabricated using physical methods, such as semicontinuous metal films obtained via electron beam physical vapor deposition. In these studies, we investigate the influence of morphology of semicontinuous silver films on their SERS properties. The morphologies studied ranged from isolated particles through percolated films to almost continuous films. We found that films below the percolation threshold (transition from dielectric-like to metal-like) made of isolated silver structures provided the largest SERS enhancement of 4-aminothiophenol (4-ATP) analyte signals. The substrate closest to the percolation threshold has the SERS signal about four times lower than the highest signal sample.

scholarly journals Dual-triggered nanoaggregates of cucurbit[7]uril and gold nanoparticles for multi-spectroscopic quantification of creatinine in urinalysis

2020 ◽  
Vol 8 (21) ◽  
pp. 7051-7058
Author(s):  
Weng-I Katherine Chio ◽  
Suresh Moorthy ◽  
Jayakumar Perumal ◽  
Dinish U. S. ◽  
Ivan P. Parkin ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Raman Spectroscopy ◽  
Surface Enhanced Raman Spectroscopy ◽  
Quantitative Detection ◽  
Vis Spectroscopy ◽  
Surface Enhanced ◽  
Surface Enhanced Raman

A novel nanosensing platform was developed for the quantitative detection of creatinine of clinically relevant concentrations via UV-Vis spectroscopy and surface-enhanced Raman spectroscopy.

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