scholarly journals Illustrating drug design using molecular modelling

2009 ◽  
Vol 31 (4) ◽  
pp. 46-47
Author(s):  
Steven Rossington

This article describes the construction of a giant protein (‘Boris’) and illustrates how by making molecular models secondary school and college students can learn hands on how drug systems and proteins interact in drug therapy treatments within the human body.

2021 ◽  
Vol 75 (1) ◽  
pp. 80-88
Author(s):  
Roger Deuber ◽  
Urs Leisinger ◽  
Amadeus Bärtsch

The topic 'Sulfa-Drugs in secondary school chemistry' has been developed in cooperation of three high schools (Kantonsschulen). Three essential aspects are covered that ideally complement each other: 1. The synthesis of sulfamethoxazole – an antibiotic 'without side effects' – as a practical course in a school laboratory; 2. An introduction to the topic 'drug design' with the question of structure, effect and side effects of sulfonamides; 3. A detailed answer to the question of how side effects can be avoided by the design of drugs using molecular modelling. Teaching materials on all topics can be downloaded free of charge from Swisseduc. ch (see box). The article discusses various possible approaches in high school chemistry along the lines of a well-established teaching unit on sulfonamides.


1991 ◽  
Vol 19 (2) ◽  
pp. 271-276
Author(s):  
Ian E. Hughes

Computers are now used routinely as tools in pharmacology, particularly in the areas of teaching, data processing and collection, information retrieval and literature searching, and in molecular modelling and drug design. Their use in these areas has enhanced research activity and has extended and increased the availability of new teaching methods. Here, their impact on the use of animals in both teaching and research is discussed. It is concluded that computers may have some potential to reduce animal experimentation in the medium to long term, but their current use as alternatives to animals has made only a marginal impact on the total number of animals utilised for experimental purposes.


1987 ◽  
Vol 15 (4) ◽  
pp. 383-389 ◽  
Author(s):  
Joan C. Roderick ◽  
Karen A. Forcht

Because of the availability of user-friendly software and the affordability of hardware, computers have become a common means of organizational communication. Users have had to change the way they process thoughts and ideas and to transfer them into hard-copy documentation. The integration of the computer into the business communication curriculum allows the instructor to provide a relevant and practical educational experience for college students. This article examines the importance of incorporating hands-on usage of a microcomputer in the business communication class and discusses computer applications and teaching strategies for text editing, punctuation review, and grammar assistance.


2014 ◽  
Vol 76 (6) ◽  
pp. 403-406
Author(s):  
Siegfried Harden ◽  
Matthew E. Grilliot

Optimal foraging theory is a principle that is often presented in the community ecology section of biology textbooks, but also can be demonstrated in the laboratory. We introduce a lab activity that uses an interactive strategy to teach high school and/or college students about this ecological concept. The activity is ideal because it engages students in a hands-on activity that teaches them a fundamental ecological principle; it can be completed in a short class period; and it utilizes a few inexpensive, easy-to-purchase supplies.


Author(s):  
Lorenz S. Neuwirth

Cellular phone distractions inhibit faculty delivering and students learning the curriculum by reducing student attendance and active engagement. Arguably, cellular phone usage during precious class times can be a risk factor for student attrition, but scarce solutions have been offered to address this problem in colleges. The Flipd App, a cellular phone distraction reduction technology was tested on 266 college students. The results showed a positive linear relationship between usage and attendance rates and a negative linear relationship between usage and ≥ 3 absence rates, and ∼10% of students resisted its use. The Flipd App may serve as a predictive educational intervention tool that increases active learning, reduces attrition, and increases retention. It may be useful in classes with less hands-on activities to reduce distractions and increase active student engagement. The Flipd App may prove useful in helping college students curb their screen time habits from the Fear of Missing Out to the Joy of Missing Out.


1978 ◽  
Vol 71 (7) ◽  
pp. 578-581
Author(s):  
Charles Lund

Buckminster Fuller has created a myriad of ideas that are highly appropriate for study at various points in the mathematics curriculum. This article describes some practical, hands-on ways in which Fuller's ideas about geodesic domes are being used in the secondary school mathematics classrooms of the St. Paul public schools.


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