scholarly journals The oxidative pathway of carbohydrate metabolism in Escherichia coli. 2. Quantitative studies of glucose 6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase

1953 ◽  
Vol 55 (1) ◽  
pp. 33-36 ◽  
Author(s):  
Dwight B. McNair Scott ◽  
S. S. Cohen
Keyword(s):  
Escherichia Coli ◽  
Carbohydrate Metabolism ◽  
Phosphogluconate Dehydrogenase ◽  
Quantitative Studies ◽  
Oxidative Pathway ◽  
Glucose 6 Phosphate Dehydrogenase

EFFECTS OF TESTOSTERONE PROPIONATE AND CYPROTERONE ACETATE ON CARBOHYDRATE METABOLISM IN RAT MAMMARY GLANDS

1980 ◽  
Vol 84 (3) ◽  
pp. 467-471
Author(s):  
N. DESHPANDE ◽  
IRENE MITCHELL
Keyword(s):  
Carbohydrate Metabolism ◽  
Cyproterone Acetate ◽  
Testosterone Propionate ◽  
Mammary Glands ◽  
Normal Mammary Gland ◽  
Inhibitory Effects ◽  
Phosphogluconate Dehydrogenase ◽  
Normal Rat ◽  
And Function ◽  
Glucose 6 Phosphate Dehydrogenase

The effects of administration of testosterone propionate on the activities of seven of the enzymes of carbohydrate metabolism in normal rat mammary glands were investigated and the validity of the results was confirmed by simultaneous injection of the hormone and cyproterone acetate. The administration of the androgen increased the activities of phosphofructokinase (PFK), glucose-6-phosphate dehydrogenase (G6PDH), 6-phosphogluconate dehydrogenase (6PGDH) and lactate dehydrogenase (LDH) in glands from both intact and from ovariectomized and adrenalectomized animals. Administration of cyproterone acetate alone resulted in a significant reduction in the activities of PFK and G6PDH and when given together with the androgen it inhibited increases in the activities of PFK, G6PDH, 6PGDH and LDH induced by testosterone. It was concluded that these results did not explain the known inhibitory effects of the androgen on normal mammary gland growth and function.

scholarly journals The effects of grass and concentrate diets on the specific activities of some enzymes of hepatic carbohydrate metabolism in sheep

1976 ◽  
Vol 35 (3) ◽  
pp. 407-411 ◽  
Author(s):  
J. Pearce ◽  
E. F. Unsworth
Keyword(s):  
Carbohydrate Metabolism ◽  
Malate Dehydrogenase ◽  
Specific Activity ◽  
Glycolytic Enzymes ◽  
Phosphogluconate Dehydrogenase ◽  
Specific Activities ◽  
Glucose 6 Phosphate Dehydrogenase

1. Feeding sheep a concentrate diet compared with grass diets increased the hepatic specific activities of the three glycolytic enzymes studied, and that of glucose-6-phosphate dehydrogenase (EC 1.1.1.49), and reduced the specific activity of D-fructose-1,6-diphosphate 1-phosphohydrolase (EC 3.1.3.11). The specific activities of phosphogluconate dehydrogenase (EC 1.1.1.43) and malate dehydrogenase (decarboxylating) (NADP) (EC 1.1.1.40) were unaffected by diet.

scholarly journals Quantitative Studies of White Matter

1961 ◽  
Vol 44 (3) ◽  
pp. 487-498 ◽  
Author(s):  
D. B. McDougal ◽  
D.W. Schulz ◽  
J.V. Passonneau ◽  
J. R. Clark ◽  
M. A. Reynolds ◽  
...  
Keyword(s):  
White Matter ◽  
Glucose Metabolism ◽  
Olfactory Bulb ◽  
Metabolic Activity ◽  
Lipid Content ◽  
O2 Uptake ◽  
Phosphogluconate Dehydrogenase ◽  
Quantitative Studies ◽  
Glucose 6 Phosphate Dehydrogenase ◽  
High Metabolic Activity

Total lipid and six enzymes closely related to the metabolism of glucose-6-phosphate have been measured in ten tracts of the rabbit. Lipid content appears to be a valid indicator of the degree of myelination. Heavily myelinated tracts have much larger amounts of glucose-6-phosphate dehydrogenase than lightly myelinated ones but there is no corresponding difference in 6-phosphogluconate dehydrogenase. In fact the ratios between the two enzymes were found to vary over a ninefold range. Hexokinase is found in largest amounts in tracts with relatively little lipid, and this tends to be true for phosphofructokinase as well. The fibrillar layer of olfactory bulb is exceptional with regard to both enzymes, and to glucose-6-phosphate dehydrogenase. The enzymes are present in amounts which are more than adequate to support glucose metabolism at a rate commensurate with the known rates of O2 uptake by various tracts. The distribution of some of the enzymes is compatible with the notion that the nodes of Ranvier are regions of high metabolic activity. A simple algebraic relationship is found to hold fairly well for the distribution of four of the enzymes among the tracts.

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