Total Body, Plasma and Erythrocyte Potassium and Leucocyte Ascorbic Acid in ‘Ultra-Fit’ Subjects

1974 ◽  
Vol 46 (4) ◽  
pp. 449-456 ◽  
Author(s):  
K. Boddy ◽  
R. Hume ◽  
Priscilla C. King ◽  
Elspeth Weyers ◽  
T. Rowan

1. Total body potassium was measured in professional football players before the football season began and at approximately mid-season. The values obtained were significantly higher than in healthy subjects taking only average exercise. There was a significant increase in body potassium as the season progressed. 2. Lean body mass was estimated by four methods and the results were compared. The values of lean body mass, as a percentage of body weight, were significantly higher than in healthy control subjects taking only average exercise and they also increased significantly over the period of the study. 3. The mean erythrocyte potassium concentration was lower pre-season than at mid-season and the pre-season value was also significantly less than in healthy controls. The values before and after vigorous exercise were not significantly different. 4. Conversely, the pre-season mean plasma potassium concentration was significantly higher than in control subjects and than the mid-season value. The mean plasma potassium concentration was higher before vigorous exercise than immediately afterwards. 5. The leucocyte count increased significantly after vigorous exercise, correlating with a decrease in leucocyte ascorbic acid content.

1975 ◽  
Vol 49 (1) ◽  
pp. 77-79
Author(s):  
R. Hesp ◽  
I. Chanarin ◽  
Christine E. Tait

1. Serial measurements of serum potassium and total-body potassium were made on eighteen patients with megaloblastic anaemia before the start of therapy and during the period of recovery. 2. In those patients who presented with an initial packed cell volume of less than 25%, a mean decrease in serum potassium of 0.4 mmol/l occurred on average within 2.5 days of the start of therapy. This was followed by a significant increase in serum potassium during the period of recovery. There was a significant increase in total-body potassium in these patients, but this could be explained by increases in erythrocyte mass, erythrocyte potassium concentration and lean body mass.


2002 ◽  
Vol 57 (3) ◽  
pp. 107-114 ◽  
Author(s):  
Pauline L. Martin ◽  
Joan Lane ◽  
Louise Pouliot ◽  
Malcolm Gains ◽  
Rudolph Stejskal ◽  
...  

1981 ◽  
Vol 33 (1) ◽  
pp. 361-363 ◽  
Author(s):  
B. Mazess ◽  
Walter W. Peppler ◽  
Charles H. Chesnut ◽  
Wil B. Nelp ◽  
Stanton H. Cohn ◽  
...  

1984 ◽  
Vol 17 (1) ◽  
pp. 63-65
Author(s):  
Akihiro Yamashita ◽  
Kazuhiro Ando ◽  
Katsuo Yoshimoto ◽  
Hideo Hidai ◽  
Kohji Shiraishi ◽  
...  

2000 ◽  
Vol 20 (6) ◽  
pp. 708-714 ◽  
Author(s):  
Cheuk-Chun Szeto ◽  
Johnathan Kong ◽  
Alan K.L. Wu ◽  
Teresa Y.H. Wong ◽  
Angela Y.M. Wang ◽  
...  

Objective To compare, in Chinese continuous ambulatory peritoneal dialysis (CAPD) patients, the creatinine kinetics method (LBM-CK) and the anthropometric method (LBM-AM) for determining lean body mass (LBM). Design Single-center cross-sectional study. Patients and Methods We studied 151 unselected CAPD patients (78 males, 73 females). We calculated LBM-CK and LBM-AM using standard formulas. The results of the two methods were then compared by the Bland and Altman method. Dialysis adequacy and other nutritional indices, including total Kt/V, weekly creatinine clearance (CCr), residual glomerular filtration rate (GFR), protein nitrogen appearance (PNA), subjective global assessment (SGA), and serum albumin, were measured simultaneously. Results The mean age of the patients was 55.6 ± 12.2 years, and the mean duration of dialysis was 33.6 ± 28.5 months. The mean body mass index (BMI) was 22.7 ± 3.7. The average LBM-AM was 43.6 ± 8.0 kg; the average LBM-CK was 33.0 ± 9.3 kg. The difference between the calculated LBM-AM and LBM-CK was 10.7 kg, with LBM-AM always giving a higher value; the limits of agreement were –5.8 kg and 27.1 kg. The difference between the two measures correlated with residual GFR (Pearson r = 0.629, p < 0.001). After normalizing for desired body weight, LBM-AM was only modestly correlated with serum albumin level. No correlations were found between overall SGA score or normalized protein nitrogen appearance (nPNA) and LBM-AM or LBM-CK. Conclusions In Chinese patients at least, a substantial discrepancy exists between LBM-AM and LBM-CK. The difference is especially marked in patients with significant residual renal function. The optimal method for determining LBM remains obscure in Chinese CAPD patients. Moreover, LBM correlated poorly with other nutritional indices. Multiple parameters should be taken into consideration in an assessment of nutritional status of CAPD patients.


2019 ◽  
Vol 34 (Supplement_3) ◽  
pp. iii19-iii25
Author(s):  
Csaba P Kovesdy

Abstract Plasma potassium concentration is maintained in a narrow range to avoid deleterious electrophysiologic consequences of both abnormally low and high levels. This is achieved by redundant physiologic mechanisms, with the kidneys playing a central role in maintaining both short-term plasma potassium stability and long-term total body potassium balance. In patients with end-stage renal disease, the lack of kidney function reduces the body’s ability to maintain normal physiologic potassium balance. Routine thrice-weekly dialysis therapy achieves long-term total body potassium mass balance, but the intermittent nature of dialytic therapy can result in wide fluctuations in plasma potassium concentration and consequently contribute to an increased risk of arrhythmogenicity. Various dialytic and nondialytic interventions can reduce the magnitude of these fluctuations, but the impact of such interventions on clinical outcomes remains unclear.


Bone ◽  
2010 ◽  
Vol 46 ◽  
pp. S80
Author(s):  
Tom Sanchez ◽  
Jingmei Wang ◽  
Chad Dudzek ◽  
George Ekker ◽  
Kathy Dudzek

1978 ◽  
Vol 54 (3) ◽  
pp. 223-231 ◽  
Author(s):  
Christine Delaporte ◽  
J. Stulzaft ◽  
C. Loirat ◽  
M. Broyer

1. Muscle electrolyte (Na, K, Cl, P) concentrations and fluid compartments of six children with Bartter's syndrome were compared with those of 17 control children. From four of the patients biopsies were taken twice, before and after treatment with potassium chloride and spironolactone. Muscle electrolytes were determined by neutron activation in tissue sampled by needle biopsy. Results were expressed in relation to fat-free dry solids. Trapped extracellular fluid was calculated from the chloride space, a normal resting membrane potential being assumed. 2. In hypokalaemic patients total muscle potassium (Km) (33·0 ± 2·1 sem) was below the normal range (43·8 ± 0·7 mmol/100 g of fat-free dry solids) in all cases. When plasma potassium was corrected, total muscle potassium returned to normal. There was a significant correlation between plasma potassium concentration and total muscle potassium (r = 0·87; P < 0·01). Total muscle sodium (Nam) was increased: 18·7 ± 2·9 mmol/100 g in hypokalaemic patients (11·3 ± 0·6 mmol/100 g of fat-free dry solids in control subjects). A negative relationship was found between Km and Nam (r = —0·85; P < 0·01). With treatment, intracellular potassium concentration remained low (142·0 mmol/l of intracellular water; control, 163·0 ± 2·4 mmol/l) despite normokalaemia and normal total muscle potassium. Muscle phosphorus (32·1 ± 1·8 mmol/100 g) was higher than in control subjects (28·1 ± 0·4 mmol/100 g of fat-free dry solids). 3. These data suggest that sodium replaces potassium in muscle of patients with Bartter's syndrome. The low intracellular potassium concentration in the binephrectomized sister of one child and in all treated children suggests that there are generalized anomalies in the handling of cations in Bartter's syndrome.


1984 ◽  
Vol 16 (2) ◽  
pp. 199
Author(s):  
S. W. Lichtman ◽  
K. R. Segal ◽  
R. L. Ruskin ◽  
E. Presta ◽  
J. Wang ◽  
...  

2015 ◽  
Vol 33 (3_suppl) ◽  
pp. 219-219
Author(s):  
Toru Aoyama ◽  
Takaki Yoshikawa ◽  
Taiichi Kawabe ◽  
Hirohito Fujikawa ◽  
Tsutomu Hayashi ◽  
...  

219 Background: Postoperative changes in body weight and composition during first 1 month after gastrectomy remained unclear. Methods: The patients who underwent gastrectomy for gastric cancer between May 2010 and October 2013 were examined. Body weight and composition were evaluated by bioelectrical impedance analyzer within 1 week before surgery (first measurement), at 1 week after surgery (second measurement), and at 1 month after surgery (third measurement). The changes of the early period were defined as the differences until the second measurement, while those of the late period as the differences from the second to the third measurement. Results: Two-hundred forty four patients were selected for this study. Total body weight loss (BWL) within 1 month was -3.4 kg and the rate of body weight at 1 month to the preoperative body weight was 94.1%. BWL was significantly greater in the early period rather than that of the late period (-2.1 kg vs -1.2 kg, p<0.001). In the early period, loss of lean body mass was significantly greater than loss of fat mass (-1.5 kg vs -0.6 kg, p<0.001). The same trend was observed regardless of type of gastrectomy and surgical approach. Conclusions: Loss of lean body mass within 1 week was a major determinant for total body weight loss at 1 month. To maintain lean body mass within 1 week and total body weight at 1 month, future trial should be focused on not the surgical approach but nutritional intervention within 1 week.


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