Intralymphocytic Sodium in Hypertensive Patients: A Significant Correlation

1979 ◽  
Vol 57 (s5) ◽  
pp. 325s-327s ◽  
Author(s):  
E. Ambrosioni ◽  
F. Tartagni ◽  
L. Montebugnoli ◽  
B. Magnani
Keyword(s):  
Blood Pressure ◽  
Normal Subjects ◽  
Sodium Concentration ◽  
The Other ◽  
Mean Blood Pressure ◽  
Normal Blood ◽  
Normal Blood Pressure ◽  
Hypertensive Patients ◽  
Normotensive Subjects

1. Intralymphocytic sodium concentration was measured in 50 patients with essential stable hypertension, 44 patients with labile hypertension and 40 subjects with normal blood pressure. 2. Intralymphocytic sodium concentration in normotensive subjects was significantly lower than in the other two groups. 3. The concentration was significantly correlated with mean blood pressure in the group as a whole and in the groups with stable and with labile hypertension. No correlation was found in normal subjects.

THE BRACHIAL TO DIGITAL BLOOD PRESSURE GRADIENT IN NORMAL SUBJECTS AND IN PATIENTS WITH HIGH BLOOD PRESSURE

1958 ◽  
Vol 36 (9) ◽  
pp. 889-893 ◽  
Author(s):  
P. Gaskell ◽  
A. M. Krisman
Keyword(s):  
Blood Pressure ◽  
Pressure Gradient ◽  
Diastolic Pressure ◽  
Systolic Pressure ◽  
Normal Subjects ◽  
Normal Blood ◽  
Control Group ◽  
Normal Blood Pressure ◽  
Hypertensive Patients ◽  
Systolic Pressure Gradient

The brachial and digital blood pressures were estimated by auscultatory techniques in 10 patients with essential hypertension and in a group of 6 subjects with normal blood pressure who were in a state of regulated peripheral vasoconstriction and again when they were in a state of regulated vasodilatation. The brachial to digital systolic and diastolic pressure gradients in both control subjects and hypertensive patients were greater when the individuals were heated than when they were cooled. The brachial to digital diastolic pressure gradient in the hypertensive patients was not significantly different from that in the subjects with normal blood pressure. However, the systolic pressure gradient was greater in the hypertensive patients than in the control group both when the individuals were heated and when they were cooled.

The Correlation of Anxiety, Dyslipidemia and Oxidative stress in Prehypertensive and Hypertensive patients

2020 ◽  
Vol 11 (2) ◽  
pp. 2614-2619
Author(s):  
Elsa Mathew ◽  
Mukkadan J. K.
Keyword(s):  
Oxidative Stress ◽  
Blood Pressure ◽  
Trait Anxiety ◽  
Normal Blood ◽  
Control Group ◽  
National Committee ◽  
Normal Blood Pressure ◽  
Hypertensive Patients ◽  
Normotensive Subjects ◽  
And Oxidative Stress

Studies have evaluated that high blood pressure kills nine million people annually Persistent. Psychological factors can be considered as a primary threat to the increase of hypertension. It may lead to cardiovascular disease, stroke and kidney disease. The current work was conducted to analyze the disparity of anxiety, dyslipidemia and oxidative stress in pre-hypertensive and hypertensive subjects. This was a cross-sectional study conducted among 180 subjects. Based on the Joint National Committee 8 Criteria, participants were divided into hypertensive patients (n₌60) and pre-hypertensive patients (n₌63). Fifty-seven healthy subjects with normal blood pressure were served as the control group. Anthropometric measurements and blood pressure were measured using the standard procedure. The biochemical parameters for measuring oxidative stress, blood glucose levels, and lipid profile were estimated. Anxiety level was assessed with the State-trait anxiety inventory (STAI) questionnaire. It is observed that the serum MalonDiAldehyde (MDA) levels (nmol/ml) were significantly higher in pre-hypertensive (3.74±0.33) and hypertensive (4.7±0.38) compared to normotensive subjects (3.05±0.38). The Superoxide Dismutase (SOD) activity (U/ml) was higher in subjects with normal blood pressure (12.67±2.31) than pre-hypertensive (11.16±2.43) and hypertensive subjects (8.98±2.32). The MDA had a significant positive correlation, and SOD had a negative association with waist-hip ratio, systolic blood pressure, diastolic blood pressure, fasting blood sugar, high-density lipoprotein, and state and trait anxiety. The present study confirmed that pre-hypertensive and hypertensive subjects suffered from more oxidative stress than normotensive subjects.

THE BRACHIAL TO DIGITAL BLOOD PRESSURE GRADIENT IN NORMAL SUBJECTS AND IN PATIENTS WITH HIGH BLOOD PRESSURE

1958 ◽  
Vol 36 (1) ◽  
pp. 889-893 ◽  
Author(s):  
P. Gaskell ◽  
A. M. Krisman
Keyword(s):  
Blood Pressure ◽  
Pressure Gradient ◽  
Diastolic Pressure ◽  
Systolic Pressure ◽  
Normal Subjects ◽  
Normal Blood ◽  
Control Group ◽  
Normal Blood Pressure ◽  
Hypertensive Patients ◽  
Systolic Pressure Gradient

The brachial and digital blood pressures were estimated by auscultatory techniques in 10 patients with essential hypertension and in a group of 6 subjects with normal blood pressure who were in a state of regulated peripheral vasoconstriction and again when they were in a state of regulated vasodilatation. The brachial to digital systolic and diastolic pressure gradients in both control subjects and hypertensive patients were greater when the individuals were heated than when they were cooled. The brachial to digital diastolic pressure gradient in the hypertensive patients was not significantly different from that in the subjects with normal blood pressure. However, the systolic pressure gradient was greater in the hypertensive patients than in the control group both when the individuals were heated and when they were cooled.

Abnormalities of peripheral venous tone in women with pregnancy-induced hypertension

1986 ◽  
Vol 70 (2) ◽  
pp. 155-157 ◽  
Author(s):  
Karen Stainer ◽  
Rachel Morrison ◽  
C. Pickles ◽  
A. J. Cowley
Keyword(s):  
Blood Pressure ◽  
Pregnant Women ◽  
Inverse Correlation ◽  
The Other ◽  
Normal Blood ◽  
Pregnancy Induced Hypertension ◽  
Normal Blood Pressure ◽  
Venous Tone ◽  
Arterial Blood ◽  
Induced Hypertension

1. Forearm venous tone was measured in two groups of pregnant women: one group with pregnancy-induced hypertension and the other group with normal blood pressure. 2. The women with pregnancy-induced hypertension were venoconstricted in the forearm (P < 0.01) compared with the pregnant women with normal blood pressure. However, there was no difference in venous tone between the women with pregnancy-induced hypertension and nonpregnant women. 3. There was an inverse correlation between mean arterial blood pressure and forearm venous tone (r = −0.581, P < 0.001) for all the pregnant women studied. Further evaluation of peripheral venous tone may provide valuable information about the pathophysiology and treatment of women with pregnancy-induced hypertension.

Relationship of arterial compliance to baroreflex function in hypertensive patients

1993 ◽  
Vol 265 (1) ◽  
pp. H232-H237 ◽  
Author(s):  
S. G. Lage ◽  
J. F. Polak ◽  
D. H. O'Leary ◽  
M. A. Creager
Keyword(s):  
Blood Pressure ◽  
Arterial Compliance ◽  
Normal Subjects ◽  
Arterial Baroreflex ◽  
Arterial Diameter ◽  
Hypertensive Patients ◽  
Baroreflex Function ◽  
Normotensive Subjects ◽  
Relationship Of ◽  
Carotid Arterial

The objectives of this study were to determine whether carotid arterial compliance is reduced in patients with hypertension and to assess whether reduced arterial compliance is related to abnormal arterial baroreflex function. Accordingly, concurrent measurements of carotid arterial diameter (via computerized high resolution B-mode ultrasonography) and blood pressure were made to determine carotid arterial compliance in 23 normotensive and 16 age-matched hypertensive patients. In addition, arterial baroreflex function was assessed in 12 of the normal subjects and nine of the hypertensive patients by measuring the infusions of nitroprusside and phenylephrine. Compared with the normotensive subjects, the patients with hypertension had reduced compliance (5.9 +/- 0.7 vs. 16.6 +/- 1.8 10(-7) m2/kPa, mean +/- SE, P < 0.001). The baroreflex slope relating the change in R-R interval to the change in systolic blood pressure during the drug infusions was less in the hypertensive than normotensive subjects (12.3 +/- 2 vs. 18.9 +/- 2 ms/mmHg, P < 0.05). Consequently, when both normotensive and hypertensive subjects were considered, there was a significant correlation between the baroreflex slope and compliance (r = 0.53, P < 0.05). However, there was no correlation between the baroreflex slope and compliance within either the normotensive group (r = 0.04, P = NS) or the hypertensive group (r = 0.43, P = NS) when analyzed separately. There was a significant correlation between age and compliance (r = -0.48, P < 0.01) but not between age and baroreflex function.(ABSTRACT TRUNCATED AT 250 WORDS)

NEPHRECTOMY IN JUVENILE HYPERTENSION ASSOCIATED WITH RENAL DISEASE

PEDIATRICS ◽  
1958 ◽  
Vol 21 (6) ◽  
pp. 941-949
Author(s):  
Herbert C. Welch ◽  
Lloyd E. Harris ◽  
James H. DeWeerd
Keyword(s):  
Blood Pressure ◽  
Renal Disease ◽  
Renal Ischemia ◽  
The Other ◽  
Normal Blood ◽  
Normal Blood Pressure ◽  
Secondary Type

Fifteen children who had hypertension apparently associated with renal ischemia underwent nephrectomy. Of 11 who presumably had unilateral renal disease, 9 were observed for at least 1 year with 8 maintaining normal blood pressure and 1 still being hypertensive. Four children were believed to have bilateral renal disease but with greater impairment of function of one kidney than the other. Removal of the more severely affected kidney in these children did not result in reduction of the blood pressure. Three of the four were dead in from 2 months to 6 years after nephrectomy and in the fourth hypertension persisted after 2½ years. The presence of hypertension in a child demands thorough investigation as to the etiology since the hypertension may be of the secondary type and therefore often curable.

scholarly journals Clinical Effects of Standard and Individualized Dialysate Sodium in Patients on Maintenance Hemodialysis

2016 ◽  
Vol 4 (2) ◽  
pp. 248-252 ◽  
Author(s):  
Natasa Eftimovska–Otovic ◽  
Olivera Stojceva-Taneva ◽  
Risto Grozdanovski ◽  
Saso Stojcev
Keyword(s):  
Blood Pressure ◽  
Sodium Concentration ◽  
The Other ◽  
Second Phase ◽  
Clinical Effects ◽  
Hypertensive Patients ◽  
Muscle Cramps ◽  
Interdialytic Weight Gain ◽  
Set Up ◽  
Dialysate Sodium

BACKGROUND: The degree to which the dialysate prescription and, in particular, the dialysate sodium concentration influences blood pressure and interdialytic weight gain (IDWG) via changes in sodium flux, plasma volume or the other parameters is not well understood. The aim of the study was to investigate whether dialysis patients will have some beneficial effects of dialysate sodium set up according to serum sodium or sodium modeling.MATERIAL AND METHODS: Ninety-two nondiabetic subjects (52 men and 40 women) performed 12 consecutive hemodialysis (HD) sessions (4 weeks) with dialysate sodium concentration set up on 138 mmol/L (standard sodium – first phase), followed by 24 sessions (second phase) wherein dialysate sodium was set up according to individualized sodium. Variables of interest were: systolic, diastolic and mean blood pressure, pulse, IDWG, thirst score – (Xerostomia Inventory (XI) and Dialysis Thirst Inventory (DTI)) and side effects (occurrence of hypotension and muscle cramps). After the first phase, the subjects were divided into 3 groups: normotensive (N=76), hypertensive (N= 11) and hypotensive (N=5) based on the average pre-HD systolic BP during the whole period of the first phase.RESULTS: Sodium individualization resulted in significantly lower blood pressure (133.61 ± 11.88 versus 153.60 ± 14.26 mmHg; p=0.000) and IDWG (2.21 ± 0.93 versus 1.87 ± 0.92 kg; p=0.018) in hypertensive patients, whereas normotensive patients showed only significant decrease in IDWG (2.21 ± 0.72 versus 2.06 ± 0.65, p=0,004). Sodium profiling in hypotensive patients significantly increased IDWG (2.45 vs. 2.74, p= 0,006), and had no impact on blood pressure. Thirst score was significantly lower in normotensive patients with individualized-sodium HD and showed no change in the other two groups. During the second phase, hypotension occurred in only 1 case and muscle cramps in 10 normotensive patients.CONCLUSION: Individualized sodium resulted in clinical benefits in normotensive and hypertensive patients.

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