Ambulant Blood Pressure: Reproducibility and the Assessment of Interventions

1980 ◽  
Vol 59 (6) ◽  
pp. 497-500 ◽  
Author(s):  
S. Mann ◽  
M. W. Millar Craig ◽  
V. Balasubramanian ◽  
P. M. M. Cashman ◽  
E. B. Raftery
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Single Dose ◽  
Diastolic Blood Pressure ◽  
Therapeutic Interventions ◽  
Daily Routine ◽  
Hypertensive Patients ◽  
Mean Values ◽  
Arterial Blood ◽  
Reliable Assessment

1. We have assessed the day-to-day reproducibility of intra-arterial blood pressure by monitoring 17 freely ambulant hypertensive patients for a period of 48 h. Eight had no change of therapeutic regimen throughout and nine took a single dose of a hypotensive agent before retiring on the second night. 2. Records were analysed to provide hourly mean values of heart rate, systolic and diastolic blood pressure. No significant differences between first and second day recordings were found except after the intervention in the second group. 3. Allowing subjects to follow their normal daily routine produces inevitable variation in their pattern of physical and other activity. However, by the use of these methods of recording and analysis, with pooled measurements from a small group of subjects, reproducibility is sufficiently good to permit the reliable assessment of therapeutic interventions.

Ramadan and blood pressure: importance of chronotherapy

2021 ◽  
Vol 28 (Supplement_1) ◽  
Author(s):  
MA Bejar ◽  
I Zairi ◽  
I Ben Mrad ◽  
B Besbes ◽  
K Mzoughi ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Dual Therapy ◽  
Average Heart Rate ◽  
Hypertensive Patients ◽  
Mean Values ◽  
Funding Sources ◽  
Cardiology Department ◽  
Group 2 ◽  
And Gender

Abstract Funding Acknowledgements Type of funding sources: None. Background During Ramadan, alterations in the daily patterns of sleep, activities and medication timing might contribute to changes in blood pressure (BP) and heart rate among hypertensive patients. The aim of this study was to examine the effect of medication timing during Ramadan on blood pressure and heart rate in hypertensive subjects taking their treatment once daily. Methods The study prospectively recruited 44 hypertensive patients between April and June 2019, followed up at the cardiology department of our   Hospital. A 24-hour pressure monitoring was carried out during two periods: prior to Ramadan and during the last ten days of Ramadan. Results We studied 29 women and 15 men, mean age was 58.7 years. 34% of the patients were diabetics and 16% had coronaropathy. 46% of the patients were on monotherapy, 43% on dual therapy and 11% on a triple antihypertensive therapy. During Ramadan, 57% of the patients took their treatment during the dinner (group1), whereas 43% took their treatment during the Shour (group 2). Average 24hour blood pressure in the whole group was 129 ± 18/74 ± 10 mmHg before Ramadan and 129 ± 19/74 ± 10 mmHg during Ramadan (p > 0.05). Daytime and nighttime mean values of systolic and diastolic blood pressure as well as mean values of heart rate were not different between both periods regardless of age and gender. However, during Ramadan, those who took their treatment after dinner had significant higher values of 24 hour systolic BP, awake systolic and diastolic BP, asleep systolic and diastolic BP than those who took their treatment with the shour (p < 0.05). Conclusion In this study, there were no significant changes in systolic and diastolic blood pressures as well as heart rate during the 2 periods. However, during Ramadan, a slight superiority of taking the treatment with the shour is observed. Average values of BP and heart rate Group 1 Group 2 p 24 hour SBP (mmHg) 134 ± 23 122 ± 6 0.017 24 hour DBP (mmHg) 76 ± 12 70 ± 5 0.052 Awake SBP (mmHg) 138 ± 23 125 ± 6 0.012 Awake DBP (mmHg) 79 ± 12 73 ± 5 0.044 Asleep SBP (mmHg) 127 ± 26 114 ± 12 0.030 Asleep DBP (mmHg) 71 ± 13 65 ± 7 0.045 24 hour average heart rate (bpm) 71 ± 7 70 ± 6 0.524 Awake average heart rate (bpm) 76 ± 7 74 ± 7 0.322 Asleep average heart rate (bpm) 65 ± 7 65 ± 7 0.931 Average values of blood pressure and heart rate in both groups Abstract Figure. 24hour course of blood pressure

The Influence of Physical Activity on Arterial Pressure during Ambulatory Recordings in Man

1980 ◽  
Vol 58 (1) ◽  
pp. 115-117 ◽  
Author(s):  
D. B. Rowlands ◽  
T. J. Stallard ◽  
R. D. S. Watson ◽  
W. A. Littler
Keyword(s):  
Physical Activity ◽  
Blood Pressure ◽  
Heart Rate ◽  
Arterial Pressure ◽  
Ambulatory Blood Pressure ◽  
Physical Activities ◽  
Hypertensive Patients ◽  
Arterial Blood ◽  
Significant Difference ◽  
Hypotensive Therapy

1. Ambulatory blood pressure recordings were made over a 48 h period on six hypertensive patients. The conditions of study were standardized, particularly with regard to physical activity, and during one period of each day the patients were randomly allocated to be active or inactive. 2. Results show that blood pressure was highest during physical activity and lowest during sleep. There was no significant difference between the arterial pressures measured during the same physical activities carried out at the same time each day. However, during the same time on consecutive days when activity was randomized, there was a significant difference between the pressure recordings during physical activity compared with those during inactivity. Heart rate changes showed a similar trend during the randomized period. 3. Physical activity and sleep have a profound effect on continuous arterial blood pressure recordings and these are independent of time alone. These observations should be taken into account when using this ambulatory system to assess hypotensive therapy.

The pharmacodynamics of dexmedetomidine in elderly cardiac patients undergoing analgosedation in the ICU

2018 ◽  
Vol 86 (4) ◽  
pp. 265
Author(s):  
Justyna Alicja Ber ◽  
Mirosław Malec ◽  
Agnieszka Bienert ◽  
Małgorzata Nowicka ◽  
Łukasz Żurański ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Single Dose ◽  
Cardiac Index ◽  
Mean Arterial Blood Pressure ◽  
Bispectral Index ◽  
Cardiac Patients ◽  
Health Conditions ◽  
Arterial Blood ◽  
Dexmedetomidine Infusion

Aim. This study aimed to evaluate the pharmacodynamics of dexmedetomidine in elderly cardiac patients.Material and Methods. Twelve patients of 60 years or older and need for analgesia after surgery or as a result of critical health conditions were included into our study. Dexmedetomidine was administered intravenously as a continuous infusion without the initial dose. At the beginning the infusion was started at the rate of 0.7 μg/kg/h and then it was continued in the range of 0.17–1.39 μg/kg/h according to desired level of sedation. Information about heart rate, systolic, diastolic and mean arterial blood pressure, bispectral index and cardiac index were collected a few minutes before, during and in 12 hours after infusion of dexmedetomidine.Results. The hemodynamic data as well as BIS level were collected from 12 patients. The duration of dexmedetomidine infusion was less than 9 hours. For each patient the reduction in blood pressure and heart rate compared to the value before dexmedetomidine infusion was observed. We did not observe bradycardia in any patient. Appropriate sedation level was achieved using only dexmedetomidine and ranged from 60 to 80. In only 2 cases it was necessary to give a single dose of another sedative.Conclusions. To conclude, in the patients’ population involved in the study, which included older cardiac patients dexmedetomidne has been shown as a sedative agent which enabled to achieve desire level of sedation in the recommended ranges without episodes of bradycardia, however hypotension events were noted.

scholarly journals Cardiovascular Changes Depending on Exercising: Strength Exercise or Nordic Walking

2018 ◽  
Vol 1 (96) ◽  
Author(s):  
Živilė Ščevinskaitė ◽  
Eugenijus Trinkūnas ◽  
Kristina Poderienė
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Health Promotion ◽  
Diastolic Blood Pressure ◽  
Training Session ◽  
Exercise Stress ◽  
Strength Exercise ◽  
Nordic Walking ◽  
Cardiovascular Changes ◽  
Arterial Blood

Background. The aim of the study was to compare the acute training effect on the cardiovascular changes under influence of different kinds of health enhancing exercising.Methods. Ten healthy males carried out two health promotion sessions by applying strength type exercising or Nordic-walk. Cardiovascular functional state was assessed before the training session and 30 minutes after the health promotion session by continuous 12-lead ECG recording while performing a Roufier Test (30 squats per 45 s) and by measuring arterial blood pressure.Results. A significant increase in the heart rate at rest was registered after the training session both after the gym training and after Nordic-walking session and reduced diastolic blood pressure values were recorded at rest and after the exercise stress test. If prior to the exercise sessions transient ischemic episode in some subjects was registered, after the training sessions the ischemic episodes were less expressed.Conclusion. Comparing the Nordic walking exercise effects with the effects of strength training exercising during the training session, less increased heart rate and systolic blood pressure were observed; a significantly higher decrease in the diastolic blood pressure, and a significantly lower degree on the short-term effects of functional ischemic myocardium were recorded.Keywords: Nordic walking, strength exercise, cardiovascular system.

scholarly journals Oral clonidine versus intravenous fentanyl in attenuation of hemodynamic responses to larngoscopy and endotracheal intubation: a comparative study

2019 ◽  
Vol 6 (3) ◽  
pp. 623
Author(s):  
Rukmini G. ◽  
Srinivas M. Reddy
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Systolic Blood Pressure ◽  
Diastolic Blood Pressure ◽  
Endotracheal Intubation ◽  
Hemodynamic Responses ◽  
Cardiovascular Parameters ◽  
Oral Clonidine ◽  
Arterial Blood ◽  
Fentanyl Group

Background: During endotracheal intubation, it has been observed that there is evolvement of the responses of the circulatory in nature. These are difficult to control using the IV anesthetic drugs. Hence various agents are tried to overcome this drawback. Objective of research work was to study efficacy of oral clonidine on hemodynamic responses compared to IV fentanyl while patients undergo larngoscopy and endotracheal intubation.Methods: The patients were allocated into two groups of 30 each. i.e. 30 patients in clonidine group and 30 patients in fentanyl group. All the patients received were pre-medicated with glycoprrolate 0.2mg, ondansetron 4mg and tramadol 1mg/kg body weight. Cardiovascular parameters (heart rate, systolic blood pressure, diastolic blood pressure, mean arterial pressure,) were recorded at the following intervals: pre-induction, after induction, at endotracheal intubation, one minute, three minutes and five minutes after intubation.Results: The heart rate was significantly more at various intervals in patients who belonged to fentanyl group and it was significantly lesser in clonidine group. The systolic blood pressure was significantly more at various intervals in patients who belonged to fentanyl group and it was significantly lesser in clonidine group. The diastolic blood pressure was significantly more at various intervals in patients who belonged to fentanyl group and it was significantly lesser in clonidine group. Similar was the case with mean arterial blood pressure.Conclusions: Clonidine has been found to be more effective than IV fentanyl in stabilizing the cardiovascular parameters. Not only that orally it is easier to administer and cost effective.

scholarly journals Potensi Madu sebagai Penurun Tekanan Darah dan Kolestrol

2019 ◽  
Vol 10 ◽  
pp. 1-5
Author(s):  
Mitha Fransiska ◽  
Jaka Fadraersada ◽  
Fajar Prasetya
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Secondary Metabolites ◽  
Diastolic Blood Pressure ◽  
Research Method ◽  
Systolic Pressure ◽  
Reduce Blood Pressure ◽  
Hypertensive Patients ◽  
Chemical Substances ◽  
Cholesterol Levels

Hypertension is an increase in systolic and diastolic blood pressure more than 140/90 mmHg. Honey has the potential to reduce blood pressure because it has 200 chemical substances. This study aims to ford the effectiveness of giving honey to reduce blood pressure and cholesterol levels in hypertensive patients, as well as knowing the content of secondary metabolites found in honey. The research method used was semi quantitative with pre and post procedurs. Honey contains secondary metabolites of alkaloids, flavonoids, tannins, and saponins. The results of the analysis of honey give a significant decrease in systolic pressure, diastole, heart rate and cholesterol levels. Consumption honey regularly effectively reduces blood pressure in hypertensive patients.

Changes in arterial blood pressure and heart rate induced by glucagon-like peptide-1-(7-36) amide in rats

1994 ◽  
Vol 266 (3) ◽  
pp. E459-E466 ◽  
Author(s):  
J. M. Barragan ◽  
R. E. Rodriguez ◽  
E. Blazquez
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Diastolic Blood Pressure ◽  
Arterial Blood Pressure ◽  
Mean Arterial Blood Pressure ◽  
Moderate Increase ◽  
Minimal Effect ◽  
Arterial Blood ◽  
Glucagon Like Peptide ◽  
Glucagon Like Peptide 1

This study was designed to determine the effects of glucagon-like peptides (GLP) on arterial blood pressure and heart rate. Although glucagon caused a minimal effect and GLP-1-(1-37) produced a moderate increase of both systolic and diastolic blood pressure, GLP-1-(7-36) amide induced the greatest increases in both parameters. Systolic and diastolic blood pressure and heart rate values increased when doses of the peptides were increased. By contrast, GLP-2 did not modify either arterial blood pressure or heart rate values. To determine whether the effects of GLP-1-(7-36) amide were mediated through catecholamines, the rats were pretreated with reserpine, propranolol, or phentolamine before administration of the peptide. In these three experimental groups, GLP-1-(7-36) amide increases mean arterial blood pressure and heart rate to the same level or even greater than that observed in nonpretreated rats. These findings indicate that GLP-1-(7-36) amide significantly increases arterial blood pressure and heart rate and that these effects are not mediated through catecholamines.

scholarly journals The Effects of Diazepam Administration on Hemodynamic Variables in Hypertensive Patients Who Undergoing Cataract Surgery

2019 ◽  
Author(s):  
Mehdi Sanatkar ◽  
Mehrdad Shorooghi ◽  
Ensiyeh Shakarami ◽  
Mehdi Mokhlesiyan
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Oxygen Saturation ◽  
Cataract Surgery ◽  
Diastolic Blood Pressure ◽  
Conscious Sedation ◽  
Topical Anesthesia ◽  
Hypertensive Patients ◽  
Midazolam Group ◽  
Hemodynamic Variables

Background: The purpose of this study was the evaluation of diazepam administration on perioperative blood pressure in hypertensive patients who undergoing cataract surgery. Methods: Eighty controlled hypertensive patients who underwent cataract surgery under topical anesthesia and conscious sedation were enrolled in this study. All patients were randomly divided to two equal size group for administration of diazepam 0.05 mg/kg (n=40, diazepam group) and midazolam 0.01 mg/kg (n=40, midazolam group) in order to conscious sedation. The systolic and diastolic blood pressure, heart rate and oxygen saturation were recorded preoperatively as baseline value, and then 5, 10 and 15 minutes after diazepam or midazolam administration. Results: There were no difference between two groups in terms of systolic, diastolic and heart rate preoperatively. Systolic and diastolic blood pressure was decreased significantly more in diazepam group compared to midazolam group perioperatively. Heart rate did not change significantly in both groups. Oxygen saturation of blood was decreased in both groups but not statistically significant.  Systolic and diastolic blood pressure variability during each period intraoperatively was lower in diazepam group compared to another group. Systolic and diastolic blood pressure of patients during recovery room in diazepam group was lower than midazolam group. Conclusion: In hypertensive patients who undergoing cataract surgery with topical anesthesia, administration of diazepam in order to conscious sedation is an effective and safe method with less perioperatively side effects

Sequential Changes in Plasma Noradrenaline during Bicycle Exercise

1980 ◽  
Vol 58 (1) ◽  
pp. 37-43 ◽  
Author(s):  
R. D. S. Watson ◽  
C. A. Hamilton ◽  
D. H. Jones ◽  
J. L. Reid ◽  
T. J. Stallard ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Supine Position ◽  
Sympathetic Activity ◽  
Plasma Noradrenaline ◽  
Bicycle Exercise ◽  
Hypertensive Patients ◽  
Arterial Blood ◽  
Exercise Blood Pressure ◽  
Venous Plasma

1. Forearm venous plasma noradrenaline, heart rate and intra-arterial blood pressure were measured sequentially during and after upright bicycle exercise in five normotensive and six hypertensive patients. 2. Plasma noradrenaline increased significantly between 4 and 8 min during exercise. 3. On stopping exercise blood pressure and heart rate decreased rapidly whilst plasma noradrenaline increased in each subject to reach a maximum at a median time of 108 s after exercise. 4. Plasma noradrenaline decreased in five of six normotensive patients between the end of exercise and 2 min after exercise performed in the supine position. 5. Evidence in favour of a reflex increase in sympathetic activity after upright exercise is discussed.

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