Assessment of broadband ultrasound attenuation in the os calcis in vitro

1990 ◽  
Vol 78 (2) ◽  
pp. 221-225 ◽  
Author(s):  
E. V. McCloskey ◽  
S. A. Murray ◽  
D. Charlesworth ◽  
C. Miller ◽  
J. Fordham ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Soft Tissues ◽  
Quantitative Computed Tomography ◽  
Broadband Ultrasound Attenuation ◽  
Mineral Density ◽  
Os Calcis ◽  
Ultrasound Attenuation ◽  
Physical Density

1. We have examined the relationship between the attenuation of broadband ultrasound in the os calcis in vitro and its bone mineral density measured by quantitative computed tomography and by physical density. 2. Broadband ultrasound attenuation was found to correlate closely with physical density (r = 0.85, P < 0.0001), but the correlation was less than that observed between quantitative computed tomography and physical density (r = 0.92, P < 0.0001). Measurements of broadband ultrasound attenuation and quantitative computed tomography were significantly correlated (r = 0.80, P < 0.0001). 3. Partial correlation analysis showed a significant relationship between broadband ultrasound attenuation and bone density, but when the effect of physical density was taken into account no significant correlation was found between broadband ultrasound attenuation and quantitative computed tomography (r = 0.08, not significant). 4. Broadband ultrasound attenuation in three prospective amputees showed a high degree of concordance between measurements in vivo and in vitro, with no interference by surrounding soft tissues. 5. The correlation between physical density and broadband ultrasound attenuation was independent of quantitative computed tomography, suggesting that the technique measures aspects of density which differ from its mineral density. Broadband ultrasound attenuation holds promise as a reproducible, rapid, radiation-free assessment of skeletal status.

Dependence of broadband ultrasound attenuation on the elastic anisotropy of trabecular bone

1998 ◽  
Vol 212 (3) ◽  
pp. 223-226 ◽  
Author(s):  
S-M Han ◽  
J-Y Rho
Keyword(s):  
Computed Tomography ◽  
Bone Mineral Density ◽  
Trabecular Bone ◽  
Bone Mineral ◽  
Elastic Anisotropy ◽  
Quantitative Computed Tomography ◽  
Broadband Ultrasound Attenuation ◽  
Mineral Density ◽  
Ultrasound Attenuation ◽  
Ultrasonic Parameters

The effect of trabecular elastic anisotropy on broadband ultrasound attenuation (BUA) and bone mineral density (BMD) was investigated with human and bovine cubic cancellous bones. Ultrasonic parameters describing trabecular anisotropy were found from the three orthogonal ultrasound velocities. BMD was measured using quantitative computed tomography. Three elastic anisotropy ratios were compared to BUA in all three directions and to BMD. The combined effect of anisotropic characteristics and BMD was also correlated with BUA. The results showed that the anisotropy ratios were significantly related to BUA (p<0.05). There was, however, no correlation between BMD and the elastic anisotropy ratios. The combination of BMD and the anisotropy produced a significantly enhanced relationship with BUA.

scholarly journals Assessing bone mineral density in vivo: quantitative computed tomography

2004 ◽  
Vol 83 (2) ◽  
pp. 222-229 ◽  
Author(s):  
D.R. Korver ◽  
J.L. Saunders-Blades ◽  
K.L. Nadeau
Keyword(s):  
Computed Tomography ◽  
Bone Mineral Density ◽  
Bone Mineral ◽  
Quantitative Computed Tomography ◽  
Mineral Density

scholarly journals In Vivo Assessment of Elasticity of Child Rib Cortical Bone Using Quantitative Computed Tomography

2017 ◽  
Vol 2017 ◽  
pp. 1-9 ◽  
Author(s):  
Y. Zhu ◽  
F. Bermond ◽  
J. Payen de la Garanderie ◽  
J.-B. Pialat ◽  
B. Sandoz ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Cortical Bone ◽  
Quantitative Computed Tomography ◽  
Strongly Correlated ◽  
Mineral Density ◽  
Direct Measurements ◽  
Conventional Tests ◽  
Unique Relationship ◽  
In Vivo Assessment

Elasticity of the child rib cortical bone is poorly known due to the difficulties in obtaining specimens to perform conventional tests. It was shown on the femoral cortical bone that elasticity is strongly correlated with density for both children and adults through a unique relationship. Thus, it is assumed that the relationships between the elasticity and density of adult rib cortical bones could be expanded to include that of children. This study estimated in vivo the elasticity of the child rib cortical bone using quantitative computed tomography (QCT). Twenty-eight children (from 1 to 18 y.o.) were considered. Calibrated QCT images were prescribed for various thoracic pathologies. The Hounsfield units were converted to bone mineral density (BMD). A relationship between the BMD and the elasticity of the rib cortical bone was applied to estimate the elasticity of children’s ribs in vivo. The estimated elasticity increases with growth (7.1 ± 2.5 GPa at 1 y.o. up to 11.6 ± 1.9 GPa at 18 y.o.). This data is in agreement with the few previous values obtained using direct measurements. This methodology paves the way for in vivo assessment of the elasticity of the child cortical bone based on calibrated QCT images.

Effect of sex steroids on peak bone density of growing rabbits

1988 ◽  
Vol 255 (4) ◽  
pp. E416-E421 ◽  
Author(s):  
V. Gilsanz ◽  
T. F. Roe ◽  
D. T. Gibbens ◽  
E. E. Schulz ◽  
M. E. Carlson ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Neutron Activation Analysis ◽  
Bone Density ◽  
Sex Steroids ◽  
Skeletal Maturity ◽  
Quantitative Computed Tomography ◽  
Peak Bone Density ◽  
New Zealand White Rabbits

To determine the effect of sex hormones on bone density (BD) during growth, longitudinal quantitative computed tomography (QCT) measurements were obtained in growing, castrated New Zealand White rabbits following administration of normal saline, testosterone, or estrogen from 6 wk of age until the time of skeletal maturity. Vertebral QCT densities increased during growth, were highest at the time of epiphyseal closure, and were significantly greater (P less than 0.001) in hormone-treated animals. In vivo QCT measurements in 12 vertebraes correlated strongly (r = 0.92) with percentage of calcium per weight assessed in vitro by neutron activation analysis.

Ultrasound Attenuation Imaging in the Os Calcis: An Improved Method

1994 ◽  
Vol 16 (2) ◽  
pp. 65-76 ◽  
Author(s):  
P. Laugier ◽  
G. Berger ◽  
P. Giat ◽  
P. Bonnin-Fayet ◽  
M. Laval-Jeantet
Keyword(s):  
Computed Tomography ◽  
Ultrasonic Attenuation ◽  
Quantitative Computed Tomography ◽  
Region Of Interest ◽  
Mineral Density ◽  
Os Calcis ◽  
Mechanical Scanning ◽  
Attenuation Imaging ◽  
Focused Transducers ◽  
Focal Zone

A complete assessment of the broadband ultrasonic attenuation (BUA) distribution within the os calcis was made using an ultrasonic mechanical scanning device with focused transducers. Measurements were performed on 12 os calces removed from fresh female cadavers. We present the first images of BUA of the os calcis. Reasonably high quality images were obtained compared to computed tomography. The resolution provided by the focused transducers is approximately 4 or 5 mm in the focal zone. Compared to dual energy X-ray absorptiometry (DEXA) or quantitative computed tomography, ultrasound imaging of the os calcis offers the possibility of controlling the placement, size and shape of the region of interest and to use multiple measurement sites. DEXA was used systematically to measure the bone mineral density (BMD) of the os calces. A highly significant correlation between BMD and BUA was found (r= 0.97 p < 0.001).

Peripheral Quantitative Computed Tomography in Human Long Bones: Evaluation of In Vitro and In Vivo Precision

1998 ◽  
Vol 13 (5) ◽  
pp. 871-882 ◽  
Author(s):  
Harri Sievänen ◽  
Virpi Koskue ◽  
Anne Rauhio ◽  
Pekka Kannus ◽  
Ari Heinonen ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Quantitative Computed Tomography ◽  
Peripheral Quantitative Computed Tomography ◽  
Long Bones
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