Characterization of microsatellite markers for the North African gundi, Ctenodactylus gundi (Rodentia: Ctenodactylidae)

2003 ◽  
Vol 3 (4) ◽  
pp. 511-513 ◽  
Author(s):  
Karen J. Nutt
Keyword(s):  
Microsatellite Markers ◽  
North African ◽  
The North

First Characterization of Congenital Myasthenic Syndrome Type 5 in North Africa

2021 ◽  
Author(s):  
khaoula rochdi ◽  
Mathieu Cerino ◽  
Nathalie Da Silva ◽  
Valerie Delague ◽  
Halima Nahili ◽  
...  
Keyword(s):  
Neuromuscular Junctions ◽  
Clinical Findings ◽  
Congenital Myasthenic Syndrome ◽  
Homozygous Mutation ◽  
North African ◽  
The North ◽  
African Populations ◽  
North African Population ◽  
Myasthenic Syndrome

Abstract Congenital myasthenic syndromes (CMS) are associated with defects in the structure and the function of neuromuscular junctions. These rare disorders can result from mutations in the collagenic tail of endplate acetylcholinesterase (COLQ) essentially associated with autosomal recessive inheritance.With the lowered cost of genetic testing and increased access to next-generation sequencing, many mutations have been reported to date. In this study we identified the first COLQ homozygous mutation c.1193T>A in the North African population. This study outlines the genetic and phenotypic features of a CMS patient in a Moroccan family. It also describes a novel COLQ missense mutation associated with CMS-5. COLQ mutations are probably underdiagnosed in these North African populations, this is an issue as CMS-5 may be treated with ephedrine, and albuterol. Indeed, patients can seriously benefit and even recover after the treatment that should be planned according to genetic tests and clinical findings.

scholarly journals Isolation and Characterization of Insecticidal Toxins from the Venom of the North African Scorpion, Buthacus leptochelys

Toxins ◽  
2019 ◽  
Vol 11 (4) ◽  
pp. 236 ◽  
Author(s):  
Yusuke Yoshimoto ◽  
Masahiro Miyashita ◽  
Mohammed Abdel-Wahab ◽  
Moustafa Sarhan ◽  
Yoshiaki Nakagawa ◽  
...  
Keyword(s):  
Sequence Similarity ◽  
Scorpion Venom ◽  
Spectrometric Analysis ◽  
North African ◽  
High Sequence Similarity ◽  
The North ◽  
Isolation And Characterization ◽  
Ms Analysis ◽  
Insect Toxicity

Various bioactive peptides have been identified in scorpion venom, but there are many scorpion species whose venom has not been investigated. In this study, we characterized venom components of the North African scorpion, Buthacus leptochelys, by mass spectrometric analysis and evaluated their insect toxicity. This is the first report of chemical and biological characterization of the B. leptochelys venom. LC/MS analysis detected at least 148 components in the venom. We isolated four peptides that show insect toxicity (Bl-1, Bl-2, Bl-3, and Bl-4) through bioassay-guided HPLC fractionation. These toxins were found to be similar to scorpion α- and β-toxins based on their N-terminal sequences. Among them, the complete primary structure of Bl-1 was determined by combination of Edman degradation and MS/MS analysis. Bl-1 is composed of 67 amino acid residues and crosslinked with four disulfide bonds. Since Bl-1 shares high sequence similarity with α-like toxins, it is likely that it acts on Na+ channels of both insects and mammals.

Characterization of insecticidal peptides from the venom of the North African scorpion, Buthacus leptochelys

Toxicon ◽  
2020 ◽  
Vol 177 ◽  
pp. S62
Author(s):  
Yusuke Yoshimoto ◽  
Masahiro Miyashita ◽  
Mohammed Abdel-Wahab ◽  
Moustafa Sarhan ◽  
Yoshiaki Nakagawa ◽  
...  
Keyword(s):  
North African ◽  
The North ◽  
Insecticidal Peptides

scholarly journals Phylogenetic placement, floral anatomy, and morphological characterization of the North African pastoral halophyte Atriplexmollis Desf. (Amaranthaceae)

2019 ◽  
Vol 43 (4) ◽  
pp. 475-486 ◽  
Author(s):  
Abderrazak TLILI ◽  
Imed SBISSI ◽  
Fayçal BOUGHALLEB ◽  
Hassen GOUJA ◽  
Teresa GARNATJE ◽  
...  
Keyword(s):  
Floral Anatomy ◽  
Morphological Characterization ◽  
North African ◽  
Phylogenetic Placement ◽  
The North

scholarly journals Development and characterization of microsatellite markers for the French endemic Angelica heterocarpa (Apiaceae) and congeneric sympatric species

2022 ◽  
Vol 15 (1) ◽  
Author(s):  
Emmanuelle Revardel ◽  
Olivier Lepais
Keyword(s):  
Microsatellite Markers ◽  
Polymorphic Marker ◽  
Sympatric Species ◽  
Enriched Library ◽  
The European Union ◽  
Evolutionary Dynamic ◽  
Marker Transferability ◽  
The North ◽  
Simple Sequence

Abstract Objective Angelica heterocarpa (Apiaceae) is a wild endemic French species with special conservation interest in the European Union. It belongs to Angelica complex genus which is widespread throughout the north temperate zone, and is sympatric with other congeneric species. The objective of this work is to develop and characterize microsatellite markers as a new tool for understanding the ecology and evolution of Angelica species complex. Results We identified simple sequence repeat (SSR) regions in a microsatellite‐enriched library from A. heterocarpa and A. sylvestris. All 16 selected SSR regions were found to amplify in these species and were highly polymorphic. Marker transferability was validated in A. razulii and A. archangelica. These markers will help us to better understand the evolutionary dynamic between rare endemics and widespread sister species, and be useful for conservation of the endemic species. Moreover, they can provide new tools for studying the numerous traditional medicinal herbs of the Angelica genus.

Skeletochronology and mark–recapture assessments of growth in the North African agamid lizard (Agama impalearis)

1999 ◽  
Vol 249 (4) ◽  
pp. 455-461
Author(s):  
El Hassan El Mouden ◽  
Mohammed Znari ◽  
Richard P. Brown
Keyword(s):  
North African ◽  
Mark Recapture ◽  
Agamid Lizard ◽  
The North
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