scholarly journals PDB4: COST-EFFECTIVENESS AND CARDIOVASCULAR RISK—AN ANALYSIS OF ROSIGLITAZONE COMPARED WITH OTHER ORAL HYPOGLYCEMIC AGENTS IN THE TREATMENT OF TYPE 2 DIABETES MELLITUS

2001 ◽  
Vol 4 (2) ◽  
pp. 113
Author(s):  
PI Oh ◽  
LG Shane
2012 ◽  
Vol 58 (3) ◽  
pp. 56-60
Author(s):  
I R Iarek-Martynova

The onset of insulin therapy is an important stage in the treatment of type 2 diabetes mellitus. Its timely beginning ensures better control of glycemia and reduces the negative consequences of chronic glucose cytotoxicity and lipotoxicity. The achievement and maintenance of the stable compensation of the disease are the indispensable conditions for successful prophylaxis and adequate treatment of chronic complications of diabetes mellitus. The ADA guidelines recommend to initiate insulin therapy at the early stages of the disease provided it is dictated by the clinical situation or combine it with the use of oral hypoglycemic agents if the targeted HbA1c levels fail to be reached despite the intake of one or more tableted preparations.


2018 ◽  
Vol 38 (5) ◽  
pp. 417-426 ◽  
Author(s):  
George Gourzoulidis ◽  
Charalampos Tzanetakos ◽  
Ioannis Ioannidis ◽  
Apostolos Tsapas ◽  
Georgia Kourlaba ◽  
...  

2017 ◽  
Vol 41 (5) ◽  
pp. 357 ◽  
Author(s):  
Min Kyong Moon ◽  
Kyu-Yeon Hur ◽  
Seung-Hyun Ko ◽  
Seok-O Park ◽  
Byung-Wan Lee ◽  
...  

2016 ◽  
Vol 63 (10) ◽  
pp. 519-526
Author(s):  
Irene Romera ◽  
Francisco Javier Ampudia-Blasco ◽  
Antonio Pérez ◽  
Bernat Ariño ◽  
Egon Pfarr ◽  
...  

2013 ◽  
Vol 59 (5) ◽  
pp. 72-80
Author(s):  
Iu Sh Khalimov

The incidence of hypoglycemia remains rather high among the population of patients with type 2 diabetes mellitus (DM2) especially in those treated with the traditional oral hypoglycemic agents. Hypoglycemia is one of the most frequent adverse events encountered by a physician dealing with diabetic (DM2) patients. At the same time, the novel approaches are currently available that allow this clinical condition to be avoided.


2013 ◽  
Vol 3 (1) ◽  
pp. 23-28
Author(s):  
Helal S. Alenezi ◽  
Mubasher Kharal ◽  
Muhammad Yousuf ◽  
Yousef Al Saleh ◽  
Salih Bin Salih

Background /Objective: The aim was to assess the glycemic control in patients with type 2 diabetes mellitus using American Diabetes Association HbA1c definition of good control of ≤ 7.0%. Methods: This retrospective study conducted in internal medicine outpatient clinics at King Abdulaziz Medical City in Riyadh, Kingdom of Saudi Arabia. All patients with type 2 diabetes mellitus attending the clinic from August 2005 to January 2006 were evaluated. Patients with HbA1c measured regularly and under anti-diabetic therapy were included in the study. Last measured HbA1c was used to evaluate diabetic control. Results: Data for 968 (81.5%) patients out of 1188 were available for analysis. Only 211 (21.8%) patients had their HbA1c within the American Diabetes Association recommended target of HbA1c ≤ 7%. Mean HbA1c was 8.98%. Patients were stratified into groups of good (HbA1c £ 7%), average (HbA1c 7.1% - 9.9%) and poor diabetic control (HbA1c ≥ 10%) included 21.8%, 46.2% and 32.0% of the study population, respectively. Mean HbA1c in patients on diabetic diet only, oral hypoglycemic agents, insulin, and oral hypoglycemic agents plus insulin was 7.62%, 8.67%, 8.92% and 9.70%, respectively. Conclusion: Majority of patients in our study did not meet the American Diabetes Association recommended target HbA1c for type 2 diabetes mellitus. Causes for this failure need to be assessed in Saudi type 2 diabetes mellitus population.


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