Symmetrical body-weight distribution training in stroke patients and its effect on fall prevention

Abstract Background The aim of this study was to collect standard reference values of the weight and the maximum pressure distribution in healthy adults aged 18–65 years and to investigate the influence of constitutional parameters on it. Methods A total of 416 healthy subjects (208 male / 208 female) aged between 18 and 65 years (Ø 38.3 ± 14.1 years) participated in this study, conducted 2015–2019 in Heidelberg. The age-specific evaluation is based on 4 age groups (G1, 18–30 years; G2, 31–40 years; G3, 41–50 years; G4, 51–65 years). A pressure measuring plate FDM-S (Zebris/Isny/Germany) was used to collect body weight distribution and maximum pressure distribution of the right and left foot and left and right forefoot/rearfoot, respectively. Results Body weight distribution of the left (50.07%) and right (50.12%) foot was balanced. There was higher load on the rearfoot (left 54.14%; right 55.09%) than on the forefoot (left 45.49%; right 44.26%). The pressure in the rearfoot was higher than in the forefoot (rearfoot left 9.60 N/cm2, rearfoot right 9.51 N/cm2/forefoot left 8.23 N/cm2, forefoot right 8.59 N/cm2). With increasing age, the load in the left foot shifted from the rearfoot to the forefoot as well as the maximum pressure (p ≤ 0.02 and 0.03; poor effect size). With increasing BMI, the body weight shifted to the left and right rearfoot (p ≤ 0.001, poor effect size). As BMI increased, so did the maximum pressure in all areas (p ≤ 0.001 and 0.03, weak to moderate effect size). There were significant differences in weight and maximum pressure distribution in the forefoot and rearfoot in the different age groups, especially between younger (18–40 years) and older (41–65 years) subjects. Discussion Healthy individuals aged from 18 to 65 years were found to have a balanced weight distribution in an aspect ratio, with a 20% greater load of the rearfoot. Age and BMI were found to be influencing factors of the weight and maximum pressure distribution, especially between younger and elder subjects. The collected standard reference values allow comparisons with other studies and can serve as a guideline in clinical practice and scientific studies.

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Measuring body weight distribution during sit-to-stand in patients with early knee osteoarthritis

Gait & Posture ◽

10.1016/j.gaitpost.2013.03.015 ◽

2013 ◽

Vol 38 (4) ◽

pp. 745-750 ◽

Cited By ~ 30

Author(s):

Lynsey D. Duffell ◽

Vivek Gulati ◽

Dominic F.L. Southgate ◽

Alison H. McGregor

Keyword(s):

Body Weight ◽

Knee Osteoarthritis ◽

Weight Distribution ◽

Sit To Stand

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Abstract TMP18: An Analysis of Fixed Dose IV Recombinant Tissue Plasminogen Activator (rtPA) and Clinical Outcome in Acute Ischemic Stroke Patients with Body Weight >100 kg: Pooled Data From Three Randomized Clinical Trials

Stroke ◽

10.1161/str.48.suppl_1.tmp18 ◽

2017 ◽

Vol 48 (suppl_1) ◽

Author(s):

Shahram Majidi ◽

Christopher Leon Guerrero ◽

Kathleen Burger ◽

Adnan Qureshi

Keyword(s):

Body Weight ◽

Ischemic Stroke ◽

Acute Ischemic Stroke ◽

Plasminogen Activator ◽

Recombinant Tissue Plasminogen Activator ◽

Fixed Dose ◽

Stroke Patients ◽

Ordinal Analysis ◽

Pooled Data ◽

Tissue Plasminogen

Background: The ASA/AHA guidelines recommend a fixed dose of 90 mg of intravenous recombinant tissue plasminogen activator(rt-PA) for acute stroke patients weighing more than 100 kilograms(kg). Previous analyses in small studies have suggested that the magnitude of benefit with IV rt-PA is lower in patients with body weight >100 kg. We determined if body weight >100 kg(and receiving <0.9 mg/kg dose) independently influence patient clinical outcomes following IV rt-PA treatment. Methods: We pooled data from IV rt-PA treatment arms from 3 randomized controlled trials; NINDS IV rt-PA study, IMS-III and Albumin Treatment of Acute Ischemic Stroke(ALIAS part 1 and 2). Patients demographic, stroke severity, comorbidities, hospital outcome and 90-day modified Rankin Scale(mRS) were compared between patients >100 kg and those ≤100 kg body weight(defined by estimated weight). Multivariate logistic regression model was used to identify independent effect of >100 kg body weight on 90-day favorable outcome(defined as mRS 0-2). An ordinal analysis of the mRS was also performed. Results: Among 977 patients treated with IV rt-PA, total of 111 subjects had body weight >100 kg(11% of all patients). The mean age(±SD) for the patients with weight >100 Kg was significantly lower(60±11 versus 68±13, p<0.0001). The median admission NIHSS score was not different between the two groups(12 versus 13, p=0.08). Patients with weight >100 kg had higher rates of history of hypertension, diabetes mellitus, and hyperlipidemia. Patients with body weight >100 kg had longer period(days±SD) of hospitalization(11±14 versus 8±7, p=0.04). Compared with patients with ≤100 kg body weight, the rate of favorable outcome at 90 days was not significantly different among patients with >100 kg body weight[OR; (95% CI): 0.99 (0.91-1.04)p=0.91], after adjusting for potential confounders. The ordinal analysis did not showed any significant shift in the distribution of scores on the mRS in patients with >100 kg body weight(OR, 0.93; 95% CI, 0.64 to 1.37; P = 0.74). Conclusion: Body weight >100 kg(and receiving <0.9 mg/kg dose) did not reduce the benefit of IV rt-PA treatment in acute ischemic stroke patients. Our results support the current recommendations in the ASA/AHA guidelines.

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Effect of erroneous body-weight estimation on outcome of thrombolyzed stroke patients

Journal of Thrombosis and Thrombolysis ◽

10.1007/s11239-020-02118-3 ◽

2020 ◽

Vol 50 (4) ◽

pp. 921-928

Author(s):

Prakash R. Paliwal ◽

Arvind K. Sharma ◽

R. N. Komal Kumar ◽

Lily Y. H. Wong ◽

Bernard P. L. Chan ◽

...

Keyword(s):

Body Weight ◽

Weight Estimation ◽

Stroke Patients

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Blood Gas Disturbances and Disproportionate Body Weight Distribution in Broilers With Wooden Breast

Frontiers in Physiology ◽

10.3389/fphys.2020.00304 ◽

2020 ◽

Vol 11 ◽

Cited By ~ 1

Author(s):

Juniper A. Lake ◽

Erin M. Brannick ◽

Michael B. Papah ◽

Cory Lousenberg ◽

Sandra G. Velleman ◽

...

Keyword(s):

Body Weight ◽

Weight Distribution ◽

Blood Gas ◽

Wooden Breast

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Coat Colour and Fittness of Rabbits on Macquarie Island

Wildlife Research ◽

10.1071/wr9820121 ◽

1982 ◽

Vol 9 (1) ◽

pp. 121 ◽

Cited By ~ 1

Author(s):

IJ Skira ◽

NP Brothers ◽

GR Copson

Keyword(s):

Body Weight ◽

Litter Size ◽

Weight Distribution ◽

Coat Colour ◽

Eye Lens ◽

Macquarie Island

Agouti rabbits constituted 84% and black rabbits 16% of the 5137 rabbits shot at Macquarie I, between 1973 and 1977. The occurrence of other coat colours was rare. There were no significant physical differences between agouti and black rabbits with respect to body weight, litter size and eye-lens weight distribution. The hypothesis that black rabbits are more robust than agouti rabbits was not substantiated.

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