On the investigation of homeopathic potencies using low resolution NMR T2 relaxation times: an experimental and critical survey of the work of Roland Conte et al

2001 ◽  
Vol 90 (01) ◽  
pp. 5-13 ◽  
Author(s):  
LR Milgrom ◽  
KR King ◽  
J Lee ◽  
AS Pinkus

AbstractWe have attempted to reproduce differences in low resolution nuclear magnetic resonance (NMR) T2 spin–spin relaxation times between homeopathically potentised and unpotentised Nitric acid (nit-ac) solutions previously reported by Conte, et al. Using similar instrumentation and experimental protocols, we have shown that it is likely that Conte's original results are attributable to experimental artifact originating in the glassware used for the manufacture of the NMR tubes.

2015 ◽  
Vol 3 (1) ◽  
pp. SA77-SA89 ◽  
Author(s):  
John Doveton ◽  
Lynn Watney

The T2 relaxation times recorded by nuclear magnetic resonance (NMR) logging are measures of the ratio of the internal surface area to volume of the formation pore system. Although standard porosity logs are restricted to estimating the volume, the NMR log partitions the pore space as a spectrum of pore sizes. These logs have great potential to elucidate carbonate sequences, which can have single, double, or triple porosity systems and whose pores have a wide variety of sizes and shapes. Continuous coring and NMR logging was made of the Cambro-Ordovician Arbuckle saline aquifer in a proposed CO2 injection well in southern Kansas. The large data set gave a rare opportunity to compare the core textural descriptions to NMR T2 relaxation time signatures over an extensive interval. Geochemical logs provided useful elemental information to assess the potential role of paramagnetic components that affect surface relaxivity. Principal component analysis of the T2 relaxation time subdivided the spectrum into five distinctive pore-size classes. When the T2 distribution was allocated between grainstones, packstones, and mudstones, the interparticle porosity component of the spectrum takes a bimodal form that marks a distinction between grain-supported and mud-supported texture. This discrimination was also reflected by the computed gamma-ray log, which recorded contributions from potassium and thorium and therefore assessed clay content reflected by fast relaxation times. A megaporosity class was equated with T2 relaxation times summed from 1024 to 2048 ms bins, and the volumetric curve compared favorably with variation over a range of vug sizes observed in the core. The complementary link between grain textures and pore textures was fruitful in the development of geomodels that integrates geologic core observations with petrophysical log measurements.


Author(s):  
В.В. Давыдов ◽  
Н.С. Мязин ◽  
В.И. Дудкин ◽  
Р.В. Давыдов

The features of the state investigation of a flowing liquid by nuclear magnetic resonance was defined. The methodology for the state investigation of the flowing medium by changing the values of the longitudinal T1 and transverse T2 relaxation times is justified. For the parameters of the registration system of the signal of nuclear magnetic resonance and magnetic fields are established relations between them. The implementation of these ratios allows to obtain a signal to noise ratio of more than 5 for carrying out measurements of T1 and T2 values in real time with an error not exceeding 1%. The results of experimental research are presented.


1986 ◽  
Vol 6 (2) ◽  
pp. 212-221 ◽  
Author(s):  
Hiroyuki Kato ◽  
Kyuya Kogure ◽  
Hitoshi Ohtomo ◽  
Masahiro Izumiyama ◽  
Muneshige Tobita ◽  
...  

Correlations between T1 and T2 relaxation times and water and electrolyte content in the normal and ischemic rat and gerbil brains were studied by means of both nuclear magnetic resonance (NMR) spectroscopic and imaging methods. In the spectroscopic experiment on excised rat brains, T1 was linearly dependent on tissue water content and T2 was prolonged in edematous tissue to a greater extent than expected by an increase in water content, showing that T2 possesses a greater sensitivity for edema identification and localization. Changes in Na+ and K+ content of the tissue mattered little in the prolongation of relaxation times. Serial NMR imaging of gerbil brains insulted with permanent hemispheric ischemia offered early lesion detection in T1- and especially T2-weighted images (detection as soon as 30 min after insult). The progressive nature of lesions was also imaged. Calculated T1 and T2 relaxation times in regions of interest correlated excellently with tissue water content ( r = 0.892 and 0.744 for T1 and T2, respectively). As a result, detection of cerebral ischemia utilizing NMR imaging was strongly dependent on a change in tissue water content. The different nature of T1 and T2 relaxation times was also observed.


1993 ◽  
Vol 118 (5) ◽  
pp. 628-631 ◽  
Author(s):  
Merle M. Millard ◽  
Dehua Liu ◽  
Michael J. Line ◽  
Miklos Faust

Magnetic resonance imaging estimates unreasonably high T2 times when creating T2 images in woody plants when tissues contain a limited amount of water. We developed a system to correct such images. Tissue distribution of proton density and states of water were determined by creating images of proton density and T2 relaxation times in summerdormant (paradormant) apple (Malus domestica Borkh.) buds. These images reveal that the proton density and water states obviously are not distributed uniformly in the bud and stem; but, the distribution of water depends greatly on the tissue type (bark, xylem, or meristem of the stem), and there are differences in the states of water even within the same tissue. At low proton density T2, calculated relaxation times were unreasonably high in tissues, with the exception of meristem of the shoot. In buds that were induced to grow and in which proton density was higher, T2 times appeared as expected. Variance of T2 times in tissues containing little water was 50 times higher than in those with a higher water content. Data with such high variance were excluded from the images; thus, the image was “corrected.” Corrected images of T2 times fit the distribution of water indicated by the proton density images well.


1980 ◽  
Vol 58 (10) ◽  
pp. 1483-1484 ◽  
Author(s):  
Marie D'Iorio ◽  
Robin L. Armstrong

New room temperature measurements of the chlorine spin–lattice and spin–spin relaxation times in the dense paramagnetic insulator K2ReCl6 yield hyperfine parameters parallel and perpendicular to the Re—Cl bond which are in acceptable agreement with the more accurate spectroscopic values extracted from nuclear magnetic resonance measurements.


2007 ◽  
Vol 50 (1) ◽  
pp. 25-36
Author(s):  
G. Holló ◽  
G. Nuernberg ◽  
P. Bogner ◽  
G. Kotek ◽  
K. Nuernberg ◽  
...  

Abstract. Title of the paper: Effect of feeding on the fatty acid composition of different fatty tissues of Hungarian Grey and Holstein Friesian bulls. II. 1H-Nuclear Magnetic Resonance (NMR) investigations In this attempt the relaxation times using 1H-NMR spectroscopy from three different (subcutaneous, perinephric and internal fat) fat depots of Hungarian Grey and Holstein Friesian extensive or intensive fattened young bulls were measured. The relaxation properties were compared with the analysis of fatty acid compostion. The different diets and the sample location have a higher influence on the relaxation times than the breed. In fat samples from extensive groups the T1-relaxation time was longer, while the T2-relaxation time was significantly shorter in intensive fed groups. The T2-relaxation time, as well as the relaxation time of T21- und T22-components were the shortest in extensive fed animals, while the proportion of T21-component was the highest in kidney fat, furthermore the difference was statistics proved. The T2-relaxation time showed a close negative relationship with the ratio of saturated fatty acids (SFA). The ratio of v21 and v22 depends on chemical composition of fat samples. In fat tissues with a high SFA percentage caused a higher proportion of v21. It is suggested that differences in fatty acid compositon of fat samples caused also alteration in the relaxation time.


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