scholarly journals Narrow-band imaging and white-light endoscopy with optical magnification in the diagnosis of dysplasia in Barrett’s esophagus: results of the Asia-Pacific Barrett’s Consortium

2014 ◽  
Vol 03 (01) ◽  
pp. E14-E18
Author(s):  
Rajvinder Singh ◽  
Mahesh Jayanna ◽  
Jennie Wong ◽  
Lee Lim ◽  
Jun Zhang ◽  
...  





2021 ◽  
Vol 93 (6) ◽  
pp. AB280-AB281
Author(s):  
Matthew Fasullo ◽  
Milan Patel ◽  
Noah Hillerbrand ◽  
Morgan Denecke ◽  
George Smallfield ◽  
...  


2017 ◽  
Vol 26 (3) ◽  
pp. 291-297 ◽  
Author(s):  
Deepanshu Jain ◽  
Sanna Fatima ◽  
Shilpa Jain ◽  
Shashideep Singhal

Barrett’s esophagus (BE) is a premalignant condition. The incidence of adenocarcinoma in BE has been reported to be between 0.1-3%. Dysplasia in BE is patchy and extensive biopsy sampling is labor intensive, low yield and does not eliminate the sampling error completely. Volumetric laser endomicroscopy (VLE) is expected to enable endoscopists to do targeted biopsy of dysplastic/cancerous lesions (not visible on white light endoscopy) among patients with BE. We reviewed 7 studies with a total of 62 subjects who had undergone VLE. Of 34 patients with available data, VLE correlated with histology in 17 subjects (50%). It missed the underlying diagnosis in one subject (2.9%). VLE led to inadvertent biopsy in 16 patients (47.1%), and led or would have led to upstaging of disease in 11 subjects (32.4%). In the entire cohort, the sensitivity, specificity, positive predictive value and negative predictive value (NPV) of VLE for diagnosis of dysplasia, buried Barrett’s or intramucosal carcinoma was 92.3%, 23.8%, 42.9% and 83.3%, respectively. High sensitivity and NPV can potentially help space out the surveillance intervals. Low specificity does lead to a high number of biopsies, which are likely less than non targeted biopsies. Volumetric laser endomicroscopy is a safe and sensitive test to identify mucosal lesions in patients with BE which are invisible under standard white light endoscopy.Abbreviations: BE: Barrett’s Esophagus; BB: Buried Barrett’s; EAC: Esophageal adenocarcinoma; EDS: Evans Dysplasia Score; EMR: Endoscopic Mucosal Resection; GERD: Gastro-esophageal reflux disease; HGD: High grade dysplasia; IMC: Intra-mucosal adenocarcinoma; LGD: Low grade dysplasia; NBI: Narrow Band Imaging; OCT-SI: Optical Coherence Tomography Scoring Index; RFA: Radiofrequency ablation; SGS: Sub-squamous glandular structures; VLE: Volumetric Laser Endomicroscopy; WLE: White Light Endoscopy.



2010 ◽  
Vol 138 (5) ◽  
pp. S-664-S-665
Author(s):  
Jose Antonio N. Almario ◽  
Emmanuel C. Gorospe ◽  
Purnima Rajan ◽  
Christian Winter ◽  
Christian Muenzenmayer ◽  
...  


Author(s):  
Carmelo Saraniti ◽  
Enzo Chianetta ◽  
Giuseppe Greco ◽  
Norhafiza Mat Lazim ◽  
Barbara Verro

Introduction Narrow-band imaging is an endoscopic diagnostic tool that, focusing on superficial vascular changes, is useful to detect suspicious laryngeal lesions, enabling their complete excision with safe and tailored resection margins. Objectives To analyze the applications and benefits of narrow-band imaging in detecting premalignant and malignant laryngeal lesions through a comparison with white-light endoscopy. Data Synthesis A literature search was performed in the PubMed, Scopus and Web of Science databases using strict keywords. Then, two authors independently analyzed the articles, read the titles and abstracts, and read completely only the relevant studies according to certain eligibility criteria. In total, 14 articles have been included in the present review; the sensitivity, specificity, positive and negative predictive values, and accuracy of pre- and/or intraoperative narrow-band imaging were analyzed. The analysis showed that narrow-band imaging is better than white-light endoscopy in terms of sensitivity, specificity, positive and negative predictive values, and accuracy regarding the ability to identify cancer and/or precancerous laryngeal lesions. Moreover, the intraoperative performance of narrow-band imaging resulted more effective than the in-office performance. Conclusion Narrow-band imaging is an effective diagnostic tool to detect premalignant and malignant laryngeal lesions and to define proper resection margins. Moreover, narrow-band imaging is useful in cases of leukoplakia that may cover a possible malignant lesion and that cannot be easily assessed with white-light endoscopy. Finally, a shared, simple and practical classification of laryngeal lesions, such as that of the European Laryngological Society, is required to identify a shared lesion management strategy. Key Points



2017 ◽  
Vol 9 (6) ◽  
pp. 273 ◽  
Author(s):  
Rajvinder Singh ◽  
Kuan Loong Cheong ◽  
Leonardo Zorron Cheng Tao Pu ◽  
Dileep Mangira ◽  
Doreen Siew Ching Koay ◽  
...  


Gut ◽  
2011 ◽  
Vol 60 (Suppl 1) ◽  
pp. A106-A106
Author(s):  
V. Subramanian ◽  
E. Telakis ◽  
J. Mannath ◽  
V. Ramappa ◽  
M. Desai ◽  
...  


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