Anti-inflammatory action of an antimicrobial model peptide that suppresses the TRIF-dependent signaling pathway via inhibition of toll-like receptor 4 endocytosis in lipopolysaccharide-stimulated macrophages

Planta Medica ◽  
2015 ◽  
Vol 81 (16) ◽  
Author(s):  
DW Shim ◽  
KH Heo ◽  
YK Kim ◽  
EJ Sim ◽  
TB Kang ◽  
...  
Keyword(s):  
Signaling Pathway ◽  
Toll Like Receptor ◽  
Model Peptide ◽  
Toll Like Receptor 4 ◽  
Anti Inflammatory ◽  
Dependent Signaling Pathway ◽  
Inflammatory Action

scholarly journals Anti-inflammatory Action of Curcumin and Its Use in the Treatment of Lifestyle-related Diseases

2019 ◽  
Vol 14 (2) ◽  
pp. 117-122 ◽  
Author(s):  
Kana Shimizu ◽  
Masafumi Funamoto ◽  
Yoichi Sunagawa ◽  
Satoshi Shimizu ◽  
Yasufumi Katanasaka ◽  
...  
Keyword(s):  
Chronic Inflammation ◽  
Peroxisome Proliferator ◽  
Toll Like Receptor ◽  
Toll Like Receptor 4 ◽  
Peroxisome Proliferator Activated Receptor ◽  
Beneficial Effects ◽  
Physiological Properties ◽  
Anti Inflammatory ◽  
Lifestyle Related Diseases ◽  
Inflammatory Action

Chronic inflammation plays a significant role in lifestyle-related diseases, such as cardiovascular diseases and obesity/impaired glucose tolerance. Curcumin is a natural extract that possesses numerous physiological properties, as indicated by its anti-inflammatory action. The mechanisms underlying these effects include the inhibition of nuclear factor-kappaB and Toll-like receptor 4-dependent signalling pathways and the activation of a peroxisome proliferator-activated receptor-gamma pathway. However, the bioavailability of curcumin is very low in humans. To resolve this issue, several drug delivery systems have been developed and a number of clinical trials have reported beneficial effects of curcumin in the management of inflammation-related diseases. It is expected that evidence regarding the clinical application of curcumin in lifestyle-related diseases associated with chronic inflammation will accumulate over time.

Anti-inflammatory effects of royal poinciana through inhibition of toll-like receptor 4 signaling pathway

2016 ◽  
Vol 34 ◽  
pp. 199-211 ◽  
Author(s):  
Satyajit Patra ◽  
Meenakshi Sundaram Muthuraman ◽  
M. Meenu ◽  
Padma Priya ◽  
Brindha Pemaiah
Keyword(s):  
Signaling Pathway ◽  
Toll Like Receptor ◽  
Toll Like Receptor 4 ◽  
Anti Inflammatory

scholarly journals Anti-Inflammatory Activity of Odina wodier Roxb, an Indian Folk Remedy, through Inhibition of Toll-Like Receptor 4 Signaling Pathway

PLoS ONE ◽  
2014 ◽  
Vol 9 (8) ◽  
pp. e104939 ◽  
Author(s):  
Durbadal Ojha ◽  
Hemanta Mukherjee ◽  
Supriya Mondal ◽  
Aditya Jena ◽  
Ved Prakash Dwivedi ◽  
...  
Keyword(s):  
Signaling Pathway ◽  
Inflammatory Activity ◽  
Toll Like Receptor ◽  
Toll Like Receptor 4 ◽  
Folk Remedy ◽  
Anti Inflammatory
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