PET/CT

2005 ◽  
Vol 44 (S 01) ◽  
pp. S51-S57 ◽  
Author(s):  
T. Beyer ◽  
G. Brix
Keyword(s):  
Diagnostic Accuracy ◽  
Radiation Exposure ◽  
Dose Reduction ◽  
Pet Imaging ◽  
Clinical Studies ◽  
Review Article ◽  
Whole Body ◽  
High Radiation ◽  
Radiation Burden ◽  
Pet Ct

Summary:Clinical studies demonstrate a gain in diagnostic accuracy by employing combined PET/CT instead of separate CT and PET imaging. However, whole-body PET/CT examinations result in a comparatively high radiation burden to patients and thus require a proper justification and optimization to avoid repeated exposure or over-exposure of patients. This review article summarizes relevant data concerning radiation exposure of patients resulting from the different components of a combined PET/CT examination and presents different imaging strategies that can help to balance the diagnostic needs and the radiation protection requirements. In addition various dose reduction measures are discussed, some of which can be adopted from CT practice, while others mandate modifications to the existing hardand software of PET/CT systems.

68Ga-PSMA-PET/CT in comparison with 18F-fluoride-PET/CT and whole-body MRI for the detection of bone metastases in patients with prostate cancer: a prospective diagnostic accuracy study

2018 ◽  
Vol 29 (3) ◽  
pp. 1221-1230 ◽  
Author(s):  
Eva Dyrberg ◽  
Helle W. Hendel ◽  
Tri Hien Viet Huynh ◽  
Tobias Wirenfeldt Klausen ◽  
Vibeke B. Løgager ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Diagnostic Accuracy ◽  
Bone Metastases ◽  
Whole Body ◽  
Diagnostic Accuracy Study ◽  
Whole Body Mri ◽  
Psma Pet ◽  
Pet Ct ◽  
Accuracy Study ◽  
18F Fluoride

scholarly journals Whole-Body 18 F-FDG PET and 18 F-FDG PET/CT in Patients with Suspected Paraneoplastic Syndrome: A Systematic Review and Meta-Analysis of Diagnostic Accuracy

2016 ◽  
Vol 58 (7) ◽  
pp. 1031-1036 ◽  
Author(s):  
Sara Sheikhbahaei ◽  
Charles V. Marcus ◽  
Roberto S. Fragomeni ◽  
Steven P. Rowe ◽  
Mehrbod S. Javadi ◽  
...  
Keyword(s):  
Systematic Review ◽  
Diagnostic Accuracy ◽  
Paraneoplastic Syndrome ◽  
Fdg Pet ◽  
Meta Analysis ◽  
Whole Body ◽  
Pet Ct ◽  
Fdg Pet Ct

scholarly journals Diagnostic accuracy of whole-body MRI/DWI image fusion for detection of malignant tumours: a comparison with PET/CT

2010 ◽  
Vol 21 (2) ◽  
pp. 246-255 ◽  
Author(s):  
Michael A. Fischer ◽  
Daniel Nanz ◽  
Thomas Hany ◽  
Caecilia S. Reiner ◽  
Paul Stolzmann ◽  
...  
Keyword(s):  
Diagnostic Accuracy ◽  
Image Fusion ◽  
Whole Body ◽  
Malignant Tumours ◽  
Whole Body Mri ◽  
Pet Ct

Comparison of Diagnostic Accuracy for TNM Stage Among Whole-Body MRI and Coregistered PET/MRI Using 1.5-T and 3-T MRI Systems and Integrated PET/CT for Non–Small Cell Lung Cancer

2020 ◽  
Vol 215 (5) ◽  
pp. 1191-1198
Author(s):  
Yoshiharu Ohno ◽  
Yoshikawa Takeshi ◽  
Daisuke Takenaka ◽  
Hisanobu Koyama ◽  
Kota Aoyagi ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Diagnostic Accuracy ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Tnm Stage ◽  
Whole Body ◽  
Small Cell Lung ◽  
Whole Body Mri ◽  
Pet Ct

Radiation exposure of patients during 68Ga-DOTATOC PET/CT examinations

2009 ◽  
Vol 48 (05) ◽  
pp. 201-207 ◽  
Author(s):  
K. Zöphel ◽  
R. Freudenberg ◽  
L. Oehme ◽  
M. Andreeff ◽  
G. Wunderlich ◽  
...  
Keyword(s):  
Pituitary Gland ◽  
Radiation Exposure ◽  
Somatostatin Receptor ◽  
Blood Pool ◽  
Biological Data ◽  
Whole Body ◽  
Physiological Uptake ◽  
Standardized Uptake Values ◽  
Pet Ct ◽  
Routine Clinical Setting

Summary Aim: Investigation of the biodistribution and calculation of dosimetry of Ga-68-DOTATOCfor patients imaged in the routine clinical setting for diagnosis or exclusion of neuroendocrine tumours. Patients, methods: Dynamic PET/CT-imaging (Biograph 16) was performed over 20 min in 14 patients (8 men, 6 women) after injection of (112 ± 22) MBq 68Ga-DOTATOC followed by whole body 3D-acquisition (8 bed positions, 3 or 4 min each) 30 min p.i. and 120 min p.i. Urinary tracer elimination was measured and blood activity was derived non-invasively from the blood pool of the heart. The relevant organs for dosimetry were spleen, kidneys, liver, adrenals, urinary bladder and pituitary gland. Dosimetry was performed using OLINDA/ EXM 1.0 software and specific organ uptake was expressed as standardized uptake values (SUVs). Results: Rapid physiological uptake of the radiotracer could be demonstrated in liver, spleen and kidneys, adrenals and pituitary gland (mean SUVs were 6, 20, 16, 10, and 4, respectively). Radiotracer elimination was exclusively via urine (16% of injected dose within 2h); no redistribution could be observed. The spleen and the kidneys received the highest radiation exposure (0.24 mSv/MBq, 0.22 mSv/MBq resp.), mean effective dose yielded 0.023 mSv/MBq. Conclusion: 68Ga-DOTATOC is used extensively for diagnosis of somatostatin receptor positive tumours because it has several advantages over the 111In-labelled ligand. The derived dosimetric values are lower than first approximations from the biological data of OctreoScan. The use of CT for transmission correction of the PET data delivers radiation exposure up to 1 mSv (low dose).

scholarly journals Diagnostic Accuracy of Colorectal Cancer Staging With Whole-Body PET/CT Colonography

JAMA ◽  
2006 ◽  
Vol 296 (21) ◽  
pp. 2590 ◽  
Author(s):  
Patrick Veit-Haibach ◽  
Christiane A. Kuehle ◽  
Thomas Beyer ◽  
Hrvoje Stergar ◽  
Hilmar Kuehl ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Diagnostic Accuracy ◽  
Ct Colonography ◽  
Cancer Staging ◽  
Whole Body ◽  
Pet Ct

scholarly journals Whole-Body PET/CT Studies with Lowered 18F-FDG Doses: The Influence of Body Mass Index in Dose Reduction

2014 ◽  
Vol 42 (1) ◽  
pp. 62-67 ◽  
Author(s):  
R. Sanchez-Jurado ◽  
M. Devis ◽  
R. Sanz ◽  
J. E. Aguilar ◽  
M. d. Puig Cozar ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Dose Reduction ◽  
Body Mass ◽  
Whole Body ◽  
Pet Ct ◽  
18F Fdg ◽  
Ct Studies

scholarly journals Occupational Radiation Exposure to Workers Used18F-FDG

2019 ◽  
Vol 29 (4) ◽  
pp. 100
Author(s):  
Ahmed Ali Wabdan
Keyword(s):  
Radiation Exposure ◽  
Radiation Risk ◽  
Whole Body ◽  
Thermoluminescent Dosimeters ◽  
Medical Physicist ◽  
Positron Emission ◽  
Pet Ct ◽  
Medical Physicists ◽  
The Mean ◽  
18F Fdg

The increasing interest of medical institutes in the development of imaging services to include the hybrid system [Positron Emission Tomography combined with Computed Tomography(PET/CT)], this system is acquiring explosive growth due to its ability to accurately detect and stage many types of cancer and follow the progress of treatments. An increasing demand for use of (18F-FDG PET) in oncology has been the main reason for its growth. The physical characteristics of positron emissions result in higher radiation risk for staff and growing use of PET/CT for diagnostic purposes increase radiation exposure. The objective of this study was to estimate the radiation exposure to the medical physicists, technicians and nurses working in three Egyptian nuclear medicine institutes under our investigations, based on the whole body collective dose measured by thermoluminescent dosimeters (TLDs) and the effective dose per study received by medical staff were measured by electronic pocked dosimeters and the finger doses by ring dosimeter during a period of six months. The (mean± SD) dose measured per PET/CT procedure were (2.45±0.137, 3.22±0.218 and 1.69±0.11) μSv for the medical physicist, technician and nurse respectively. The (mean± SD) dose measured per MBq of 18F-FDG were (7.35±0.43, 9.73±0.66 and 5.13±0.33) nSv/MBq for the medical physicist, technician and nurse respectively. The (mean± SD) finger dose measured per 18F-FDGPET/CT scans were (179.9±24.94, 8.82±2.912 and 24.15±4.164) μSv for the medical physicist, technician and nurse respectively.

Radiation exposure of patients undergoing whole-body FDG-PET/CT examinations

2014 ◽  
Vol 53 (05) ◽  
pp. 217-220 ◽  
Author(s):  
D. Noßke ◽  
U. Leche ◽  
G. Brix
Keyword(s):  
Radiation Exposure ◽  
Effective Dose ◽  
Fdg Pet ◽  
Radiation Risk ◽  
Whole Body ◽  
Organ Doses ◽  
Weighting Factors ◽  
Pet Ct ◽  
Conversion Coefficients ◽  
Fdg Pet Ct

SummaryAim: Reinvestigation of the radiation exposure of patients undergoing whole-body [18F]FDG-PET/CT examinations pursuant to the revised recommendations of the ICRP. Methods: Conversion coefficients for equivalent organ doses were determined for realistic anthropomorphic phantoms of reference persons. Based on these data, conversion coefficients for the effective dose were calculated using the revised tissue-weighting factors that account for the different radiation susceptibilities of organs and tissues, and the redefinition of the group ‘remainder tissues’. Results: Despite the markedly changed values of the equivalent organ doses estimated for FDG and of the tissue-weighting factors, the conversion coefficient for the effective dose resulting from FDG administration decreases only slightly by 10 %. For whole-body CT scans it remains even unchanged. Conclusion: The updated dose coefficients provide a valuable tool to easily assess the generic radiation risk of patients undergoing whole- body PET/CT (or PET/MRI) examinations and can be used, amongst others, for protocol optimization.

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