scholarly journals Maternal Outcome in Mitral Valve Disease with Pulmonary Hypertension: Two Case Reports

2018 ◽  
Vol 03 (02/03) ◽  
pp. 204-208
Author(s):  
Anuradha Alagandala ◽  
Daya Vaswani ◽  
Vuduthala Bharadwaj ◽  
Kousalya Chakravarthy
Keyword(s):  
Pulmonary Embolism ◽  
Heart Disease ◽  
Mitral Stenosis ◽  
Maternal Morbidity ◽  
Fatal Case ◽  
Morbidity And Mortality ◽  
First Case ◽  
Asymptomatic Patients ◽  
Maternal Morbidity And Mortality ◽  
In Pregnancy

AbstractChronic rheumatic heart disease is still the leading cause of heart disease complicating pregnancy in the developing countries. The physiologic changes in pregnancy and stress induced by the increase in cardiac output can cause asymptomatic patients with mitral stenosis to decompensate, especially in the third trimester. Severity of mitral stenosis is reflected by the decrease in the valve area and increase in the right ventricular systolic pressures (RVSPs). Venous thromboembolism (VTE) is two to five times more common in the postpartum period, and the risk is high with cesarean delivery. Pulmonary embolism in pregnancy can cause severe maternal morbidity and mortality. We describe two cases of severe mitral stenosis complicating pregnancy with grossly elevated RVSP. The first case is the successful management of a second gravida, presenting with severe mitral stenosis with RVSP 80 mm Hg, and the second, a fatal case of a 26-year-old para 1, live 1, delivered by cesarean section, presenting with massive fatal pulmonary embolism on 13th postoperative day (POD) with RVSP 90 mm Hg. A multidisciplinary approach involving the cardiologist, obstetrician, and obstetric anesthesiologist is crucial for management of severe mitral stenosis complicating pregnancy, to decrease the maternal morbidity and mortality during peripartum period.

scholarly journals Venomous Snakebite in Pregnancy and Good Outcome –A Case Report

2016 ◽  
Vol 27 (2) ◽  
pp. 86-88
Author(s):  
Mohammad Ali ◽  
Md Robed Amin ◽  
Mohammad Belalul Islam ◽  
Mohammad Haresur Rahman ◽  
Md Mahbubul Islam Mojumdar
Keyword(s):  
Case Report ◽  
Maternal Morbidity ◽  
Medical Literature ◽  
Morbidity And Mortality ◽  
Good Outcome ◽  
Fetal Wastage ◽  
Maternal Morbidity And Mortality ◽  
In Pregnancy

Worldwide occurrence of snakebite in pregnancy is little known in medical literature. Furthermore to the best of our knowledge there is no case report on Krait envenomation in pregnancy in Bangladesh. It carries significant fetal wastage and maternal morbidity and mortality. Here we report a mutligravida aged 27 years at her 24 weeks of gestation with krait bite with neuroparesis with good obstetrical outcome.Bangladesh J Medicine Jul 2016; 27(2) : 86-88

scholarly journals Pulmonary complications for women with sickle cell disease in pregnancy: systematic review and meta-analysis

Thorax ◽  
2020 ◽  
Vol 75 (7) ◽  
pp. 568-575 ◽  
Author(s):  
Sivarajini Inparaj ◽  
Mickey Buckingham ◽  
Laura Oakley ◽  
Paul T Seed ◽  
Sebastian Lucas ◽  
...  
Keyword(s):  
Systematic Review ◽  
Sickle Cell Disease ◽  
Sickle Cell ◽  
Maternal Morbidity ◽  
Meta Analysis ◽  
Pulmonary Complications ◽  
Morbidity And Mortality ◽  
Cell Disease ◽  
Maternal Morbidity And Mortality ◽  
In Pregnancy

BackgroundSickle cell disease (SCD) is a multisystem disease characterised by vaso-occlusive crisis, chronic anaemia and a shorter lifespan. More patients with SCD are living till reproductive age and contemplating pregnancy. Pulmonary complications in pregnancy are significant causes of maternal morbidity and mortality but yet this has not been systematically quantified. A systematic review and meta-analysis were conducted to quantify the association between SCD and pulmonary complications in pregnancy.MethodsMEDLINE, EMBASE, Web of Science, Cochrane and Maternity and Infant Care databases were searched for publications between January 1998 and April 2019. Observational studies involving at least 30 participants were included. Random-effects models were used for statistical meta-analysis.FindingsTwenty-two studies were included in the systematic review and 18 in the quantitative analysis. The meta-analysis included 3964 pregnancies with SCD and 336 559 controls. Compared with women without SCD, pregnancies complicated by SCD were at increased risk of pulmonary thromboembolism (relative risk (RR) 7.74; 95% CI 4.65 to 12.89). The estimated prevalence of acute chest syndrome and pneumonia was 6.46% (95% CI 4.66% to 8.25%), with no significant difference between the HbSS and HbSC genotypes (RR 1.42; 95% CI 0.90 to 2.23).InterpretationThis meta-analysis highlighted a strong association between SCD and maternal pulmonary complications. Understanding the risks of and the factors associated with pulmonary complications would aid preconceptual counselling and optimal management of the condition in pregnancy, thereby reducing associated maternal morbidity and mortality.PROSPERO registration numberCRD42019124708.

scholarly journals A rare case of severe pulmonary hypertension in pregnancy

2020 ◽  
Vol 9 (11) ◽  
pp. 4707
Author(s):  
Ramna Banerjee ◽  
Farheen Rahman
Keyword(s):  
Pulmonary Hypertension ◽  
Maternal Morbidity ◽  
Rare Case ◽  
Heart Diseases ◽  
Tertiary Care ◽  
Morbidity And Mortality ◽  
Care Hospital ◽  
Severe Pulmonary Hypertension ◽  
Maternal Morbidity And Mortality ◽  
In Pregnancy

Heart diseases in pregnancy have always been a source of major concern for both the patients as well as the caregivers because of the high risk of maternal morbidity and mortality and the need for specialist care by a multidisciplinary team preferably in a tertiary care hospital. Amongst the whole gamut of heart diseases, pulmonary hypertension is associated with high maternal morbidity and mortality (in the order of 20% in some studies) and hence is considered a contraindication for pregnancy. We report a rare case of a lady at 36 weeks gestation in her second pregnancy, with a previous caesarean section, who was incidentally diagnosed with severe pulmonary hypertension (PAP-110 mmHg) during her antenatal check-up in the third trimester of pregnancy and survived without any major complications after being promptly referred to and treated in a multispecialty hospital. Her previous pregnancy was absolutely uneventful and even in this pregnancy she had very mild symptoms as compared to the severity of the disease found on further investigation.

scholarly journals FETOMATERNAL OUTCOME IN PREGNANCY WITH CARDIAC DISEASE

2021 ◽  
Vol 5 (7) ◽  
Author(s):  
Kalyani K Bafna ◽  
Kanaklata Nakum ◽  
Aditi Vithal
Keyword(s):  
Heart Disease ◽  
Pregnant Women ◽  
Cardiac Disease ◽  
Maternal Morbidity ◽  
Nyha Class ◽  
Mode Of Delivery ◽  
Fetal Outcome ◽  
Morbidity And Mortality ◽  
Maternal Complications ◽  
Maternal Morbidity And Mortality

Objective(S): Cardiac disease is an important cause of maternal morbidity and mortality in both antepartum as well as in postpartum period. Incidence of heart disease with pregnancy is <1%. Aim of this study is to determine maternal complications with heart disease, mode of delivery & fetal complications. Materials & Methodology: This is a retrospective study conducted at Gopinath Maternity Home, Sir-T Hospital, Bhavnagar. From May 2020- April 2021. All pregnant women with various cardiac disease (previously established or diagnosed during pregnancy) who came to labor room or OPD are included. Result: 30 pregnant women out of 2683 deliveries were identified with cardiac disease giving prevalence of 1.12% in this study. 15(50%) women belonging to NYHA class-1 & 8(26.6%) belonged to NYHA class 2. Class 3(3 patients =10%) & class 4(4patients= 13.3%) were admitted immediately. 18(60%) women were case of valvular heart disease, out of which 12(66.6%) cases were of RHD, 2(11.1%) were MS, 3(16.6%) AS, 1(5.5%) MR. 10(33.33%) cases were congenital heart disease. Maternal mortality were 4(13.33%). Out of 30 cases, 18(69.2%) women had LSCS, 6(23.07%) had vaginal delivery,2(7.7%) had vaccum & 3(10.3%) had abortion. Out of 26 deliveries 2(7.7%) were IUFD, 6(23.07%) Preterm, 7(26.9%) IUGR. Total there were 9(37.5%) NICU admissions. Conclusion: Prognosis of pregnancy with heart disease has improved but management of it is still a challenge for obstetricians. Pre-conceptional counseling plays an important role by benefiting women with severe heart disease and thus help in reducing maternal morbidity and mortality. Keywords:  cardiac disease, maternal outcome, fetal outcome

scholarly journals A 25-Year-Old Pregnant Lady with Heart Disease

2017 ◽  
Vol 7 (1) ◽  
pp. 42-43
Author(s):  
Jamila Khatun
Keyword(s):  
Heart Disease ◽  
Cardiac Disease ◽  
Maternal Morbidity ◽  
Congenital Heart ◽  
Combined Treatment ◽  
Healthy Baby ◽  
Maternal Morbidity And Mortality ◽  
Grade Ii ◽  
Rheumatic Heart ◽  
In Pregnancy

Cardiac disease in pregnancy is an important cause of maternal morbidity and mortality. Rheumatic heart disease and congenital heart disease are the commonest cardiac problems in our country. Here we report a 25-year-old lady who presented with 36 weeks of pregnancy with severe mitral stenosis with grade II mitral regurgitation and pulmonary hypertension. With combined treatment of cardiologist and obstetrician the patient delivered a healthy baby without any complication. She was discharged on 7th postnatal day with satisfactory condition.J Enam Med Col 2017; 7(1): 42-43

scholarly journals Cardiovascular diseases during pregnancy and delivery

2013 ◽  
Vol 66 (11-12) ◽  
pp. 507-513
Author(s):  
Zoran Stajic ◽  
Zdravko Mijailovic ◽  
Mirjana Bogavac ◽  
Biljana Lazovic ◽  
Maja Stojanovic
Keyword(s):  
Cardiovascular Disease ◽  
Cardiovascular Diseases ◽  
Maternal Mortality ◽  
Pregnant Women ◽  
Cardiovascular System ◽  
Maternal Morbidity ◽  
Morbidity And Mortality ◽  
Circulating Blood Volume ◽  
Maternal Morbidity And Mortality ◽  
In Pregnancy

Introduction. Nowadays, cardiovascular diseases are the leading cause of maternal morbidity and mortality in the current obstetric practice. Physiologically Adapted Mechanisms of the Cardiovascular System in Pregnancy. It is normal that during pregnancy some physiological adaptive changes of the cardiovascular system occur and they may contribute to the deterioration of the clinical cardiac status of a patient with preexisting or acquired cardiovascular disease. The most prominent adaptive mechanisms include the increase of circulating blood volume, decrease of peripheral vascular resistance and decrease of plasma colloid-oncotic pressure. Most Frequent Diseases of the Cardiovascular System in Pregnancy. Due to these changes, pregnant women are prone to tachycardia, palpitations and peripheral edema. Maternal counseling is obligatory for each pregnant woman in order to decrease the maternal morbidity and mortality. The most important predictors of maternal mortality for pregnant women with cardiovascular diseases are severity of pulmonary hypertension, hemodynamic significance of valvular lesion, cyanosis and functional status in heart failure. Cardiovascular diseases in pregnant women may be congenital or acquired. The most frequent congenital cardiac diseases are atrial and ventricular septal defects as well as persistent ductus arteriosus. These diseases are mainly diagnosed and corrected before the pregnancy, or left untreated if hemodynamically insignificant. The most frequent acquired cardiovascular diseases during pregnancy include arrhythmias, ischemic heart disease, rheumatic mitral stenosis and insufficiency, arterial hypertension and aortic dissection. Conclusion. In all cases of pregnancy associated with cardiovascular diseases, early recognition of cardiovascular disease is crucial, as well as correct diagnosis and referral to a tertiary centre equipped for a multidisciplinary approach of specialists experienced in high-risk pregnancies and deliveries in order to prevent maternal mortality.

scholarly journals 639 Co-occuring opioid and methamphetamine use disorder and severe maternal morbidity and mortality in Utah

2021 ◽  
Vol 224 (2) ◽  
pp. S401-S402
Author(s):  
Marcela Smid ◽  
Amanda A. Allshouse ◽  
Kristine Campbell ◽  
Michelle P. Debbink ◽  
Adam G. Gordon ◽  
...  
Keyword(s):  
Maternal Morbidity ◽  
Morbidity And Mortality ◽  
Severe Maternal Morbidity ◽  
Methamphetamine Use ◽  
Maternal Morbidity And Mortality ◽  
Methamphetamine Use Disorder
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