scholarly journals Biomechanical Alterations Caused by Musculo’s Keletal Bleedings.

1977 ◽  
Author(s):  
P. Hofmann ◽  
G. Schumpe ◽  
H.H. Brackmann
Keyword(s):  
Significant Interaction ◽  
Weight Bearing ◽  
Skeletal Growth ◽  
Skeletal System ◽  
Radiological Findings ◽  
Bleeding Events ◽  
Coagulation Defect ◽  
Biomechanical Parameters ◽  
Muscular Imbalance ◽  
Initial Change

10,000 bleeding events into the musculo-skeletal system of 500 hemophiliacs were brought into statistical relation with the clinical and radiological findings. A significant interaction between alteration of distinct biomechanical parameters and the frequency of musculo-skeletal - especially intraarticular - hemorrhages was seen. The initial change due to intraarticular hemorrhage was found to be muscular imbalance leading to a) malpositions of the articular axes, b)excentric restriction of movement, c) reduced weight bearing capacity. Unphysiological gait results and induces an increased frequency of local bleedings as well as biomechanically predetermined overstresses within ipsilateral joints and muscles. The latter induces joint or muscle bleedings in the presence of hemophilic coagulation defect. The alterations mentioned above are amplified by skeletal growth.

Giant parathyroid adenoma diagnosed by brown tumor, a clinical manifestation of primary hyperparathyroidism: a case report

2021 ◽  
pp. 1-8
Author(s):  
Banu Yigit ◽  
Mert Tanal ◽  
Bulent Citgez
Keyword(s):  
Case Report ◽  
Primary Hyperparathyroidism ◽  
Secondary Hyperparathyroidism ◽  
Parathyroid Adenoma ◽  
Benign Lesion ◽  
Brown Tumor ◽  
Skeletal System ◽  
Radiological Findings ◽  
Facial Bones ◽  
Osteitis Fibrosa Cystica

Abstract Brown tumor (BT) is the pathological expression of osteitis fibrosa cystica owing to primary and secondary hyperparathyroidism (HPT). It is a rare benign lesion of skeletal system that usually affects the facial bones, clavicles, ribs, pelvis and extremities. The purpose of this case report is to present the clinical, pathological and radiological findings of BT, rarely seen in adults, originating from the giant parathyroid adenoma and emerging as the first clinical sign of HPT. The patient underwent a successful parathyroidectomy operation and on the first postoperative day, the patient was discharged without any complications. Continuous...

A functional comparison of conventional knee–ankle–foot orthoses and a microprocessor-controlled leg orthosis system based on biomechanical parameters

2014 ◽  
Vol 40 (2) ◽  
pp. 277-286 ◽  
Author(s):  
Thomas Schmalz ◽  
Eva Pröbsting ◽  
Roland Auberger ◽  
Gordon Siewert
Keyword(s):  
Knee Flexion ◽  
Weight Bearing ◽  
Swing Phase ◽  
Flexion Angle ◽  
Foot Orthoses ◽  
Joint Moments ◽  
Level Walking ◽  
Stance Control ◽  
Ankle Foot Orthoses ◽  
Biomechanical Parameters

Background: The microprocessor-controlled leg orthosis C-Brace enables patients with paretic or paralysed lower limb muscles to use dampened knee flexion under weight-bearing and speed-adapted control of the swing phase. Objectives: The objective of the present study was to investigate the new technical functions of the C-Brace orthosis, based on biomechanical parameters. Study design: The study enrolled six patients. The C-Brace orthosis is compared with conventional leg orthoses (four stance control orthoses, two locked knee–ankle–foot orthoses) using biomechanical parameters of level walking, descending ramps and descending stairs. Methods: Ground reaction forces, joint moments and kinematic parameters were measured for level walking as well as ascending and descending ramps and stairs. Results: With the C-Brace, a nearly natural stance phase knee flexion was measured during level walking (mean value 11° ± 5.6°). The maximum swing phase knee flexion angle of the C-Brace approached the normal value of 65° more closely than the stance control orthoses (66° ± 8.5° vs 74° ± 6.4°). No significant differences in the joint moments were found between the C-Brace and stance control orthosis conditions. In contrast to the conventional orthoses, all patients were able to ambulate ramps and stairs using a step-over-step technique with C-Brace (flexion angle 64.6° ± 8.2° and 70.5° ± 12.4°). Conclusion: The results show that the functions of the C-Brace for situation-dependent knee flexion under weight bearing have been used by patients with a high level of confidence. Clinical relevance The functional benefits of the C-Brace in comparison with the conventional orthotic mechanisms could be demonstrated most clearly for descending ramps and stairs. The C-Brace orthosis is able to combine improved orthotic function with sustained orthotic safety.

scholarly journals Tuberculosis Mimicking Bone Tumor

2013 ◽  
Vol 11 (1) ◽  
pp. 49-51
Author(s):  
Bidur Gyawali ◽  
Bishnu Dev Sharma ◽  
Nirab Kayastha ◽  
Amit Joshi
Keyword(s):  
Bone Tumor ◽  
Pathological Examination ◽  
Malignant Bone Tumor ◽  
Distal Forearm ◽  
Granulomatous Lesion ◽  
Skeletal System ◽  
Medial Aspect ◽  
Radiological Findings ◽  
Open Biopsy ◽  
Delay In Diagnosis

Tuberculosis has been greatest mimicker in medicine. Tuberculosis of skeletal system can simulate a malignancy both clinically and radiologically. As tuberculosis of Ulna is a rare, we report a case of unifocaldiaphyseal tubercular osteomyelitis of Ulna which resembled malignancy in a 60yrs male with mildly painful, gradually increasing swelling over dorso medial aspect of left distal forearm since 5 months duration. Radiological findings were suggestive of aggressive bone tumor and biopsy was planned. Tru-cut biopsy revealed sterile pus and open biopsy was performed. Intraoperatively there was cheesy pus with flakes of sequestra and multiple breaches in ulna cortex. Histo-pathological examination revealed chronic inflammatory granulomatous lesion suggestive of tubercular osteomyelitis. We report this case not only because tuberculosis of ulna is rare, but also because it mimicked malignant bone tumor both clinico-radiologically leading to delay in diagnosis and institution of treatment. Medical Journal of Shree Birendra Hospital; Jan-June 2012/vol.11/Issue1/49-51 DOI: http://dx.doi.org/10.3126/mjsbh.v11i1.7791

scholarly journals Erdheim-Chester Disease: A Case Report and Review of the Literature

2020 ◽  
Vol 10 ◽  
pp. 37
Author(s):  
Hema Merai ◽  
David Collas ◽  
Ashish Bhagat ◽  
Uday Mandalia
Keyword(s):  
Systemic Disease ◽  
Review Of The Literature ◽  
Skeletal System ◽  
Radiological Findings ◽  
Rare Form ◽  
Birbeck Granules ◽  
Erdheim Chester Disease ◽  
Life Threatening ◽  
Erdheim Chester ◽  
Chester Disease

Erdheim-Chester disease (ECD) is a rare form of non-Langerhans’ cell histiocytosis characterized by xanthogranulomatous infiltration of foamy histiocytes surrounded by fibrosis. ECD may be asymptomatic or present as a multi-systemic disease with life-threatening manifestations, most commonly involving the skeletal system. Immunohistochemical staining demonstrates cells that are CD68+, CD1a–, and S100– with an absence of Birbeck granules. We report a case of a 69-year old male patient who presented with neurological symptoms – eventually thought to be separate to his diagnosis of ECD. It represents the ability to diagnose ECD based just on radiological findings in an otherwise asymptomatic individual.

scholarly journals Classic homocystinuria: clinical, biochemical and radiological observations, and therapeutic outcome of 24 Saudi patients

1999 ◽  
Vol 5 (6) ◽  
pp. 1196-1203
Author(s):  
M. A. Al Essa ◽  
M. S. Rashed ◽  
P. T. Ozand
Keyword(s):  
Vitamin B6 ◽  
Vascular System ◽  
Clinical Findings ◽  
Research Centre ◽  
Skeletal System ◽  
Normal Range ◽  
Radiological Findings ◽  
Ectopia Lentis ◽  
System Involvement ◽  
King Faisal Specialist Hospital

We considered the clinical, biochemical and radiological findings, and response to pyridoxine [vitamin B6]of 24 classic homocystinuric patients [15 females, 9 males]diagnosed at King Faisal Specialist Hospital and Research Centre. Common clinical findings included ectopia lentis [20 patients], skeletal system involvement [18 patients], vascular system involvement [9 patients]and mental retardation [all patients to varying degrees]. A number of unusual findings were reported. The parents of 21 patients were first-degree relatives and 19 patients had at least one other family member affected by the same disease. Only 4 patients responded to pyridoxine; their methionine level decreased to almost normal range

A Developmental Study of Intonation Recognition

1968 ◽  
Vol 11 (4) ◽  
pp. 825-832 ◽  
Author(s):  
Marilyn M. Corlew
Keyword(s):  
Significant Interaction ◽  
Multiple Choice ◽  
Semantic Content ◽  
First Grade ◽  
Choice Test ◽  
Developmental Study ◽  
Multiple Choice Test ◽  
The Third ◽  
Matching Test ◽  
Better Than

Two experiments investigated the information conveyed by intonation from speaker to listener. A multiple-choice test was devised to test the ability of 48 adults to recognize and label intonation when it was separated from all other meaning. Nine intonation contours whose labels were most agreed upon by adults were each matched with two English sentences (one with appropriate and one with inappropriate intonation and semantic content) to make a matching-test for children. The matching-test was tape-recorded and given to children in the first, third, and fifth grades (32 subjects in each grade). The first-grade children matched the intonations with significantly greater agreement than chance; but they agreed upon significantly fewer sentences than either the third or fifth graders. Some intonation contours were matched with significantly greater frequency than others. The performance of the girls was better than that of the boys on an impatient question and a simple command which indicates that there was a significant interaction between sex and intonation.

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