scholarly journals Principles and Applications of Fat Grafting in Plastic Surgery

2019 ◽  
Vol 33 (03) ◽  
pp. 147-154 ◽  
Author(s):  
Amjed Abu-Ghname ◽  
Aurelia Trisliana Perdanasari ◽  
Edward M. Reece
Keyword(s):  
Plastic Surgery ◽  
Clinical Applications ◽  
Fat Grafting ◽  
Soft Tissue Augmentation ◽  
Fat Transplantation ◽  
Basic Principles ◽  
Autologous Fat ◽  
Autologous Fat Transfer ◽  
Autologous Fat Transplantation ◽  
Injection Techniques

AbstractAutologous fat transplantation has become increasingly popular in recent years. Its biocompatable properties and availability made it a widely used treatment modality for soft tissue augmentation and volume replacement in both reconstructive and aesthetic plastic surgery. Multiple protocols and clinical applications have been described in the literature, with wide variations in the harvesting, processing, and injection techniques. In this review, the authors will discuss the basic principles and clinical applications of fat grafting in plastic and reconstructive surgery. The article will then conclude with a discussion of fat grafting limitations as well as potential future applications, giving the reader a well-rounded understanding of autologous fat transfer.

scholarly journals Treatment of “En Coupe De Sabre “ Linear Scleroderma. Soft Tissue Augmentation and Regeneration by Autologous Fat Transfer

2021 ◽  
pp. 30
Author(s):  
◽  
Keyword(s):  
Stem Cells ◽  
Soft Tissue ◽  
Fat Grafting ◽  
Soft Tissue Augmentation ◽  
Congenital Deformity ◽  
Autologous Fat Grafting ◽  
Fat Transfer ◽  
Autologous Fat ◽  
Autologous Fat Transfer ◽  
Linear Scleroderma

Aim: Frontal linear scleroderma, also known as ‘‘en coup de sabre,’’ is a congenital deformity characterized by atrophy and furrowing of the skin of the front parietal area above the level of the eyebrows. In most cases it occurs as a single paramedian line that may be associated with hypoplasia of underlying structures and facial hemiatrophy. In case of a wide lesion many reconstructive strategies have been proposed. The modern approach is aimed at augmentation of the tissue deficiency by using lipostructure and tissue regeneration. Autologous fat transfer (AFT) seems to be an effective strategy to restore the normal volume and contour of the face while providing a source of adipose-derived stem cells (ADSCs) with a multilineage differentiation potential. Methods: In this report, we present a rare case of linear scleroderma en coupe de sabre which was successfully managed with three stages of autologous fat grafting. Conclusion: The proposed uses for ADSCs in tissue repair and regeneration are quite impressive. Recent works on ADSCs would suggest that adult cells may prove to be an equally powerful regenerative tool in treating congenital and acquired maxillofacial disorders. More importantly, physicians, researchers and international associations need to cooperate in informing clinicians about what practices are based on evidence and to encourage support of additional research. There is increasing interest in a possible therapeutic effect of ADSCs from processed lipoaspirate for a wide spectrum of clinical applications in the facial and craniofacial area. AFT can be used in any facial area where soft tissue is lacking or where there is scarring, producing natural and long-lasting results. Mesenchymal stem cells represent a great tool in regenerative medicine. However, more definitive studies are needed to answer specific questions regarding the best technique to be used and the role of ADSCs. Autologous fat grafting provides a safe and easy approach for the treatment of linear scleroderma en coup de sabre, long-term clinically satisfactory results can be obtained.

scholarly journals Hybrid mastopexy: improving outcomes on implant-based augmentation mastopexy with fat

2021 ◽  
Author(s):  
Giuseppe Cuccia ◽  
Carola Maria Gagliardo ◽  
Marco Romeo ◽  
Benedetto Di Trapani
Keyword(s):  
Breast Augmentation ◽  
Breast Implant ◽  
Fat Grafting ◽  
Safe Procedure ◽  
Fat Transplantation ◽  
Autologous Fat ◽  
Ultrasound Evaluation ◽  
Autologous Fat Transplantation ◽  
Breast Shape ◽  
Augmentation Mastopexy

Abstract Background Autologous fat transplantation for breast augmentation represents an increasingly interesting technique in plastic surgery. Only a few standardized procedures are available. Hybrid augmentation mastopexy combines the benefits of autologous fat transplantation and implant-based breast augmentation mastopexy, reducing implant-related complications and prothesis size. Herein, we describe our surgical approach as a “hybrid aesthetic surgery.” Methods A retrospective analysis of all patients who underwent hybrid breast augmentation and lifting with simultaneous fat grafting was carried out. Clinical outcomes, ultrasound evaluation of upper pole fullness, aesthetic postoperative results, and complications were examined. Results Eighteen patients with a mean age of 33 years (range: 24–52 years) and mean BMI of 25.8 kg/m2 (range: 21.4–32.1 kg/m2) were included in this study. Mean injected fat volume per breast was 115 cc (range: 78–144 cc). Patients were followed up for a mean of 9.4 months (range: 6–24 months). No fat necrosis or major complications were encountered during the follow-up. Patient satisfaction was high in terms of breast shape, size, and coverage of the breast implant. No recurrence of ptosis was observed yet and no secondary revision surgery was performed. Conclusions Hybrid mastopexy augmentation is an effective and safe procedure that combines the benefits of autologous fat grafting and implant-based breast augmentation. The transfer of autologous soft tissue allows obtaining a natural breast shape, reducing the onset of rippling and prothesis size. The reduction of prothesis size prevents ptosis recurrence but provides the desired projection. This reliable option improves long-term breast shape with elevated patient’s satisfaction. Level of evidence: Level IV, therapeutic study.

Autologous Fat Transplantation for Aesthetic Breast Augmentation: A Systematic Review and Meta-Analysis

2021 ◽  
Author(s):  
Yingjie Wu ◽  
Feng Hu ◽  
Xueping Li ◽  
Guoqian Yin
Keyword(s):  
Cohort Studies ◽  
Breast Augmentation ◽  
Meta Analysis ◽  
Cochrane Library ◽  
Fat Transplantation ◽  
Term Survival ◽  
Autologous Fat ◽  
Autologous Fat Transfer ◽  
Autologous Fat Transplantation ◽  
Aesthetic Breast

Abstract Background Autologous fat transfer (AFT) has already become a part of clinical practice for aesthetic breast augmentation, even though evidence regarding its efficacy is still lacking. Objectives To determine the current worldwide status and efficacy, techniques, and oncologic safety on this subject. Methods PubMed, EMBASE, and Cochrane Library databases were searched to identify all relevant studies. Results Eighty-four articles published between 1987 and April 2020, consisting of 6468 patients, were included, and 64 studies consisting of 5162 unique patients were included in the meta-analysis. Most studies had a low level of evidence (levels 2b–5); In this meta-analysis, there were 17 prospective cohort studies, four retrospective cohort studies, six case-control studies, and 38 case series. The publications were from 21 countries. Indications for autologous fat transplantation were aesthetic augmentation (93.2%) and congenital malformation (6.8%). Among the 5162 patients, two cases (0.04%) of cancer were reported. The meta-analysis revealed very high overall patient and surgeon satisfaction rates of 93% and 87%, respectively. Overall, only 1.56 sessions were needed to achieve the desired result. Long-term survival was calculated to be about 60–70% at 1-year follow-up. Only 8% of procedures resulted in clinical complications, and 5% of patients required biopsy because of abnormal clinical or radiological findings. Conclusions Autologous fat transplantation seems to be a major tool in aesthetic breast augmentation. Preoperative patient selection is essential but under-reported. Future research should focus on evaluating the technical and patient factors influencing the rate of fat survival and its oncological safety.

Autologous adipose tissue (lipofilling) in treatment of linear scleroderma (literature review)

2020 ◽  
pp. 15-17
Author(s):  
A. R. Misbakhova ◽  
N. E. Manturova ◽  
N. N. Murashkin ◽  
A. G. Stenko
Keyword(s):  
Adipose Tissue ◽  
Fat Grafting ◽  
Scientific Interest ◽  
Fat Transplantation ◽  
Medical Specialties ◽  
Autologous Fat ◽  
Autologous Fat Transplantation ◽  
Biological Substance ◽  
Day By Day ◽  
Indications For Use

Autologous fat is a biological substance that attracting increased scientific interest. Autologous fat considered as ideal filler due to its biocompatibility without risk of an allergic reaction or rejection. Likewise, this substance could be obtained easily, and costs are relatively low. Therapeutic indications for use fat grafting appear day by day, as it is recognized as an effective, reliable methodology and enhancing of areas and pathologies of application in medical specialties. The analysis results show that autologous fat transplantation gives a possibility to compensate for aesthetic and functional signs caused by facial scleroderma.

scholarly journals Platelet-Rich Plasma: Principles and Applications in Plastic Surgery

2019 ◽  
Vol 33 (03) ◽  
pp. 155-161 ◽  
Author(s):  
Amjed Abu-Ghname ◽  
Aurelia Trisliana Perdanasari ◽  
Matthew J. Davis ◽  
Edward M. Reece
Keyword(s):  
Plastic Surgery ◽  
Platelet Rich Plasma ◽  
New Technology ◽  
Clinical Applications ◽  
Great Promise ◽  
Clinical Settings ◽  
Skin Rejuvenation ◽  
Basic Principles ◽  
Reconstructive Plastic Surgery ◽  
Reconstructive Plastic

AbstractPlatelet-rich plasma (PRP) is an autogenously harvested liquid platelet concentrate extracted from a patient's peripheral blood that contains higher than baseline concentrations of growth factors and cytokines. This innovative new technology has demonstrated great promise in the field of plastic surgery, and its use has been evaluated in several clinical settings including wound healing, hair restoration, and skin rejuvenation. The goal of this article is to explain the biology behind PRP and to review the basic principles involved in its preparation. This will be followed by a discussion of some clinical applications of PRP in both aesthetic and reconstructive plastic surgery.

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