Autologous adipose tissue (lipofilling) in treatment of linear scleroderma (literature review)

2020 ◽  
pp. 15-17
Author(s):  
A. R. Misbakhova ◽  
N. E. Manturova ◽  
N. N. Murashkin ◽  
A. G. Stenko
Keyword(s):  
Adipose Tissue ◽  
Fat Grafting ◽  
Scientific Interest ◽  
Fat Transplantation ◽  
Medical Specialties ◽  
Autologous Fat ◽  
Autologous Fat Transplantation ◽  
Biological Substance ◽  
Day By Day ◽  
Indications For Use

Autologous fat is a biological substance that attracting increased scientific interest. Autologous fat considered as ideal filler due to its biocompatibility without risk of an allergic reaction or rejection. Likewise, this substance could be obtained easily, and costs are relatively low. Therapeutic indications for use fat grafting appear day by day, as it is recognized as an effective, reliable methodology and enhancing of areas and pathologies of application in medical specialties. The analysis results show that autologous fat transplantation gives a possibility to compensate for aesthetic and functional signs caused by facial scleroderma.

scholarly journals Principles and Applications of Fat Grafting in Plastic Surgery

2019 ◽  
Vol 33 (03) ◽  
pp. 147-154 ◽  
Author(s):  
Amjed Abu-Ghname ◽  
Aurelia Trisliana Perdanasari ◽  
Edward M. Reece
Keyword(s):  
Plastic Surgery ◽  
Clinical Applications ◽  
Fat Grafting ◽  
Soft Tissue Augmentation ◽  
Fat Transplantation ◽  
Basic Principles ◽  
Autologous Fat ◽  
Autologous Fat Transfer ◽  
Autologous Fat Transplantation ◽  
Injection Techniques

AbstractAutologous fat transplantation has become increasingly popular in recent years. Its biocompatable properties and availability made it a widely used treatment modality for soft tissue augmentation and volume replacement in both reconstructive and aesthetic plastic surgery. Multiple protocols and clinical applications have been described in the literature, with wide variations in the harvesting, processing, and injection techniques. In this review, the authors will discuss the basic principles and clinical applications of fat grafting in plastic and reconstructive surgery. The article will then conclude with a discussion of fat grafting limitations as well as potential future applications, giving the reader a well-rounded understanding of autologous fat transfer.

scholarly journals Improvement of the Survival of Human Autologous Fat Transplantation by Adipose-Derived Stem-Cells-Assisted Lipotransfer Combined with bFGF

2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Aimei Jiang ◽  
Ming Li ◽  
Wenjing Duan ◽  
Yilong Dong ◽  
Yanmei Wang
Keyword(s):  
Stem Cells ◽  
Adipose Tissue ◽  
Histological Analysis ◽  
Angiogenic Factors ◽  
Fat Graft ◽  
Adipose Derived Stem Cells ◽  
Fat Transplantation ◽  
Autologous Fat ◽  
Fat Grafts ◽  
Autologous Fat Transplantation

Adipose-derived stem cells (ASCs) transplanted along with autologous adipose tissue may improve fat graft survival; however, the efficacy of ASCs has been diluted by low vascularization. This study was designed to test the hypothesis that basic fibroblast growth factor (bFGF) may improve the effects of ASCs because it owns the property to boost angiogenesis. In the present study, human fat tissues were mixed with ASCs, ASCs plus 100 U bFGF, or medium as the control and then injected subcutaneously into immunologically compromised nude mice for 12 weeks. Our findings demonstrated that mixture with the ASCs significantly increased the weight and volume of the fat grafts compared to control grafts, and histological analysis revealed that both ASCs and ASCs plus bFGF grafts consisted predominantly of adipose tissue and had significantly less fibrosis but greater microvascular density compared with control and also grafts mixed with ASCs had a high expression of angiogenic factors. More importantly, the bFGF treated fat grafts shown elevate in survival, vascularization, and angiogenic factors expression when compared with the grafts that received ASCs alone. These results indicated that bFGF together with ASCs can enhance the efficacy of autologous fat transplantation and increase blood vessel generation involved in the benefits from bFGF.

scholarly journals Hybrid mastopexy: improving outcomes on implant-based augmentation mastopexy with fat

2021 ◽  
Author(s):  
Giuseppe Cuccia ◽  
Carola Maria Gagliardo ◽  
Marco Romeo ◽  
Benedetto Di Trapani
Keyword(s):  
Breast Augmentation ◽  
Breast Implant ◽  
Fat Grafting ◽  
Safe Procedure ◽  
Fat Transplantation ◽  
Autologous Fat ◽  
Ultrasound Evaluation ◽  
Autologous Fat Transplantation ◽  
Breast Shape ◽  
Augmentation Mastopexy

Abstract Background Autologous fat transplantation for breast augmentation represents an increasingly interesting technique in plastic surgery. Only a few standardized procedures are available. Hybrid augmentation mastopexy combines the benefits of autologous fat transplantation and implant-based breast augmentation mastopexy, reducing implant-related complications and prothesis size. Herein, we describe our surgical approach as a “hybrid aesthetic surgery.” Methods A retrospective analysis of all patients who underwent hybrid breast augmentation and lifting with simultaneous fat grafting was carried out. Clinical outcomes, ultrasound evaluation of upper pole fullness, aesthetic postoperative results, and complications were examined. Results Eighteen patients with a mean age of 33 years (range: 24–52 years) and mean BMI of 25.8 kg/m2 (range: 21.4–32.1 kg/m2) were included in this study. Mean injected fat volume per breast was 115 cc (range: 78–144 cc). Patients were followed up for a mean of 9.4 months (range: 6–24 months). No fat necrosis or major complications were encountered during the follow-up. Patient satisfaction was high in terms of breast shape, size, and coverage of the breast implant. No recurrence of ptosis was observed yet and no secondary revision surgery was performed. Conclusions Hybrid mastopexy augmentation is an effective and safe procedure that combines the benefits of autologous fat grafting and implant-based breast augmentation. The transfer of autologous soft tissue allows obtaining a natural breast shape, reducing the onset of rippling and prothesis size. The reduction of prothesis size prevents ptosis recurrence but provides the desired projection. This reliable option improves long-term breast shape with elevated patient’s satisfaction. Level of evidence: Level IV, therapeutic study.

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