scholarly journals Update on the Diagnosis and Treatment of Idiopathic Intracranial Hypertension

2019 ◽  
Vol 39 (06) ◽  
pp. 682-691
Author(s):  
Sarah R. Ahmad ◽  
Heather E. Moss

AbstractAdvances in ophthalmic diagnostics and results of interventional clinical trials are shifting diagnosis and management of idiopathic intracranial hypertension (IIH) to be more technology- and evidence-based. In this article, the evidence supporting current diagnostic criteria, evaluation, and medical and surgical management of IIH are reviewed.

2012 ◽  
Vol 2012 (dec13 1) ◽  
pp. bcr2012007949-bcr2012007949
Author(s):  
Z. Zakaria ◽  
E. Fenton ◽  
M. T. Sattar

2018 ◽  
Vol 89 (10) ◽  
pp. A10.1-A10
Author(s):  
Scotton Sangeeta ◽  
Liczkowski Anthony ◽  
Mollan Susan P ◽  
Sinclair Alexandra J

ObjectiveTo quantify the rate of diagnostic error amongst patients with IIH. Additionally to identify factors contributing to diagnostic error.MethodsSequential patients referred with a diagnosis of IIH to the Birmingham tertiary neuro-ophthalmology IIH clinic were prospectively included (October 2013- February 2017) A diagnostic error taxonomy tool was applied to cases referred as ‘definite’ or ‘possible’ IIH. Discrepancy between referred and final diagnosis were recorded. Results212 patients were referred, (96.2% female), 138/212 (65%) with definite IIH and 74/212 (35%) with possible IIH. Of those diagnosed with definite IIH 25% were not IIH and out of those diagnosed with possible IIH 57% were not IIH. Reasons for diagnostic error included incorrectly identifying papilloedema where in fact pseudopapilloedema existed and diagnosing IIH following an isolated lumbar puncture (LP) pressure >25 cmCSF (but in the absence of other diagnostic criteria for IIH). Misdiagnosis lead to 43% receiving unnecessary acetazolamide (or other diuretics) and 14% having multiple LPs.ConclusionsWe noted a high diagnostic error rate amongst IIH patients referred to a tertiary centre for ongoing management. Where there is doubt about the presence of true papilloedema early specialist review may reduce unnecessary treatment and LP’s.


2021 ◽  
Vol 96 (1) ◽  
pp. 30-35
Author(s):  
Sehee Kim ◽  
Hae-Rim Kim ◽  
Sang-Heon Lee ◽  
Hong Ki Min

Adult-onset Still’s disease (AOSD) is an obscure disease that is usually diagnosed after the exclusion of other febrile diseases, including other autoimmune, infectious, and malignant diseases. Although definitive diagnostic criteria and treatment guidelines for AOSD are thus far lacking, the typical manifestations of AOSD have been identified and effective medications for remission and maintenance have been proposed. The pathophysiology of the AOSD is unclear, but diagnostic criteria and treatment guidelines for AOSD can be established by determining its core etiology and conducting clinical trials of previously tested immunosuppressants and biologics.


2016 ◽  
Vol 11 (2) ◽  
pp. 135-149 ◽  
Author(s):  
Paolo Gionchetti ◽  
Axel Dignass ◽  
Silvio Danese ◽  
Fernando José Magro Dias ◽  
Gerhard Rogler ◽  
...  

Author(s):  
Jenna L. Schleien ◽  
Gina Dimitropoulos ◽  
Katharine L. Loeb ◽  
Daniel Le Grange

It is well recognized that diagnostic assessments and evidence-based treatment approaches developed for anorexia nervosa (AN) or bulimia nervosa (BN) do not apply as well to atypical and complex eating disorders. This chapter provides a description of the evolution of diagnostic criteria for eating disorder presentations that do not fall under the categories of AN and BN. The chapter begins with an overview of atypical and complex comorbid eating disorders, including historical development, diagnostic criteria, and symptom presentation. Following this conceptual overview, the chapter discusses the challenges of applying results from randomized clinical trials for AN or BN to individuals affected by atypical eating disorders or comorbid diagnoses such as anxiety and substance abuse. The chapter concludes by outlining some possible solutions to the conundrum of identifying effective solutions for individuals with atypical and complex comorbid eating disorders.


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