scholarly journals PROLONGED PYREXIA WITH ACUTE RENAL INSULT - UNRAVELING THE PUZZLE AND SOLVING THE ENIGMA

2014 ◽  
Vol 04 (02) ◽  
pp. 129-132
Author(s):  
Raghava Sharma
Keyword(s):  
Renal Failure ◽  
Renal Injury ◽  
Peripheral Blood ◽  
Fever Of Unknown Origin ◽  
Unknown Origin ◽  
Acute Renal Injury ◽  
Middle Aged ◽  
Blood Eosinophilia ◽  
Oliguric Renal Failure ◽  
Peripheral Blood Eosinophilia

Abstract:A middle aged man with prolonged pyrexia was referred to us with a diagnosis of FUO (Fever of unknown origin). He was evaluated by various investigations and a diagnosis of Tuberculosis was established. On anti tubercular treatment (ATT) he developed complication of acute renal injury –non oliguric renal failure, from which he recovered fully after the puzzle was successfully solved & managed accordingly. Even though he was proved to have rifampicin induced acute intersticial nephritis(AIN) by biopsy , he had varied & unconventional presentation like without oliguria, without peripheral blood eosinophilia, and more so particularly on the maiden administration of rifampicin. Thus our case highlights the importance of quickly establishing the cause for FUO, and also need for greater vigilance on part of physicians to solve unconventional presentations of complications arising out of treatment.

scholarly journals Incidence of Acute Renal Failure in Full Term Neonates with Birth Asphyxia

2019 ◽  
Vol 4 (1) ◽  
pp. 671-674
Author(s):  
Chandra Bhushan Jha ◽  
Akhil Tamrakar
Keyword(s):  
Renal Failure ◽  
Acute Renal Failure ◽  
Serum Creatinine ◽  
Renal Injury ◽  
Urine Output ◽  
Birth Asphyxia ◽  
Full Term ◽  
Acute Renal Injury ◽  
Term Neonates ◽  
Oliguric Renal Failure

Introduction: Birth asphyxia is an eventuality having far reaching consequences in the neonatal period. Hypoxia and ischemia can cause damage to almost every tissue and organ in the body and various target organs involved. Renal insult is a recognized complication of birth asphyxia and carries a poor prognosis. Timely detection of renal dysfunction and appropriate management may favorably alter the prognosis in many neonates with birth asphyxia. Objective: The present study was done to find out the incidence of acute renal failure in the full term neonates with birth asphyxia. Methodology: A cross sectional study was conducted at Birat Medical College Teaching Hospital, Morang, Nepal from 1st September 2017 to 28th February 2018. Fifty full term neonates born with Apgar score of <6 at 5 minutes and fulfilling inclusion criteria were enrolled in the study. Asphyxiated neonates having Serum creatinine >1.5gm/dl or urine output<1ml/kg/hr were labeled as cases of Acute Renal Failure. Blood sample for serum creatinine was collected at 24hrs, 48 hrs and 72 hrs of life. Results A total of 50 term asphyxiated neonates were enrolled in the present study. Among them 54% and 46% were males and females respectively with male to female ratio of 1.2:1. In the present study 62% of cases developed acute renal failure in either of the first three days of life with mean urine output 1.02±0.27ml/kg/hr and mean serum creatinine of 1.49±0.32 mg/dL. The incidence of oliguric renal failure was 52% and non oliguric renal failure was 48%.The association between serum creatinine and urine output was statistically significant. Conclusion: In the present study birth asphyxia has been an important cause of neonatal acute renal injury, revealing 31 (62%) cases. Monitoring urine output and serum creatinine has helped in detecting the asphyxiated neonates with acute renal injury in the early stage.

A Case of Allergic Granulomatous Angiitis with Peripheral Blood Eosinophilia Revealing Resistance to Systemic Steroid

2006 ◽  
Vol 68 (1) ◽  
pp. 19-23
Author(s):  
Yuki SUZUKI ◽  
Hideaki WATANABE ◽  
Amane KITAMI ◽  
Hirohiko SUEKI ◽  
Masafumi IIJIMA ◽  
...  
Keyword(s):  
Peripheral Blood ◽  
Systemic Steroid ◽  
Granulomatous Angiitis ◽  
Blood Eosinophilia ◽  
Allergic Granulomatous Angiitis ◽  
Peripheral Blood Eosinophilia

Malignant Fibrous Histiocytoma Associated with Peripheral Blood Eosinophilia

Oncology ◽  
1986 ◽  
Vol 43 (4) ◽  
pp. 230-233 ◽  
Author(s):  
Stefan Serke ◽  
Monika Brenner ◽  
Robert Zimmermann ◽  
Hartmut Lobeck
Keyword(s):  
Malignant Fibrous Histiocytoma ◽  
Peripheral Blood ◽  
Fibrous Histiocytoma ◽  
Blood Eosinophilia ◽  
Peripheral Blood Eosinophilia

Allergic altered reactivity in the early neonatal period

1982 ◽  
Vol 63 (4) ◽  
pp. 11-13
Author(s):  
A. G. Shamova ◽  
R. M. Bakhtiarova
Keyword(s):  
Enzymatic Activity ◽  
Social Factors ◽  
Peripheral Blood ◽  
Neonatal Period ◽  
Allergic Reactions ◽  
Blood Eosinophilia ◽  
Early Neonatal Period ◽  
Peripheral Blood Eosinophilia

In 138 newborns with toxic (allergic) erythema, the mediation of allergic reactions by social factors was established. On the 2nd day of life, an allergically altered reactivity is clinically manifested, which is also expressed by an altered picture of peripheral blood (eosinophilia, lymphocytosis) and indicators of the enzymatic activity of leukocytes.

scholarly journals Toxocariasis in children: epidemiological, clinical and laboratory aspects

2020 ◽  
Vol 4 (11) ◽  
pp. 670-675
Author(s):  
A.O. Andreeva ◽  
◽  
N.V. Golovchenko ◽  
A.S. Zhuravlev ◽  
◽  
...  
Keyword(s):  
Peripheral Blood ◽  
Laboratory Data ◽  
Enzyme Linked Immunosorbent Assay ◽  
Blood Eosinophilia ◽  
Rights Protection ◽  
Human Wellbeing ◽  
Consumer Rights ◽  
Positive Rate ◽  
Peripheral Blood Eosinophilia ◽  
Research Institute

Aim: to optimize the diagnosis of toxocariasis based on the analysis of epidemiological, clinical and laboratory data in children with the infestation. Patients and Methods: the analysis of official statistical data for the period of 2014–2018, literature sources, a retrospective analysis of 57 medical records of patients (40 children and 17 adults) who received treatment and diagnostic in the clinic of the Rostov Research Institute of Microbiology and Parasitology of the Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing in 2015–2018 was conducted. Results: a decrease in the incidence of newly diagnosed infestation cases was revealed (registered in the clinic of the Rostov Research Institute of Microbiology and Parasitology of the Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing). It correlated with official statistics (r=0.9, p=0.05). Based on clinical and laboratory examination, the diagnosis was established in 26 patients (45.6%). Among patients with a verified diagnosis of toxocariasis, the proportion of children aged 1 years and 1 months to 10 years old, was 96%. An analysis of epidemiological data showed that 76% of children had close contact with the soil. The infestation occurred in the form of latent toxocariasis in 36% of patients. In more than half of the cases, the disease was clinically manifested by geophagy (56.0%). A permanent laboratory parameter was the eosinophilic leukemoid reaction in patients with toxocariasis. Peripheral blood eosinophilia ranged from 15.66.2±9.31% in latent toxocariasis to 25.5±15.0 % in visceral toxocariasis. The positive rate in ELISA with Toxocara antigen was higher than that in the group of patients with visceral toxocariasis. However, there was no correlation between the eosinophilia level and positive rate (r=0.1, p=0.05). Conclusion: in areas where the incidence of toxocariasis and environmental contamination with invasive helminth eggs are high, it is advisable to perform tests of the peripheral blood in children at least one time per year in the autumn for timely diagnosis of infestation. The use of ELISA with Toxocara antigen is reasonable in the cases of peripheral blood eosinophilia. KEYWORDS: toxocariasis, statistics, incidence, eosinophilia, enzyme-linked immunosorbent assay, Toxocara antigen. FOR CITATION: Andreeva A.O., Golovchenko N.V., Zhuravlev A.S. Toxocariasis in children: epidemiological, clinical and laboratory aspects. Russian Medical Inquiry. 2020;4(11):670–675. DOI: 10.32364/2587-6821-2020-4-11-670-675.

scholarly journals Concurrent sensitization to Aspergillus Fumigatus in tropical pulmonary eosinophilia

2016 ◽  
Vol 81 (1-2) ◽  
Author(s):  
Sunil K. Chhabra ◽  
Devi Jyoti Dash
Keyword(s):  
Aspergillus Fumigatus ◽  
Severe Asthma ◽  
Lung Tissue ◽  
Peripheral Blood ◽  
Allergic Bronchopulmonary Aspergillosis ◽  
Pulmonary Eosinophilia ◽  
Blood Eosinophilia ◽  
Future Risk ◽  
Serum Total Ige ◽  
Peripheral Blood Eosinophilia

<p>Tropical pulmonary eosinophilia (TPE) is characterized by lung tissue and peripheral blood eosinophilia. Serum total IgE is also markedly increased in TPE. However, an association with asthma or other hypersensitivity conditions has not been described. During the diagnostic workup of three patients eventually confirmed to have TPE, hypersensitivity to the fungus, <em>Aspergillus Fumigatus </em>was found. However, there was no evidence of diseases of aspergillus hypersensitivity such as severe asthma with fungal sensitization (SAFS) and allergic bronchopulmonary aspergillosis (ABPA). This association however raises the possibility of a future risk of these potentially serious allergic respiratory manifestations.</p><p><strong>Riassunto</strong></p><p>L’eosinofilia polmonare tropicale (TPE) è caratterizzata da tessuto polmonare e eosinofilia nel sangue periferico. Anche il siero IgE totale è notevolmente aumentato in TPE. Tuttavia, un’associazione con asma o altre condizioni di ipersensibilità non è stata descritta. Durante l'iter diagnostico di tre pazienti, che alla fine si sono rivelati presentare TPE, ipersensibilità al fungo, è stato trovato l’<em>Aspergillus fumigatus</em>. Tuttavia, non vi era alcuna evidenza di malattie di <em>Aspergillus</em> ipersensibilità come l'asma grave con sensibilizzazione fungina (SAF) e aspergillosi broncopolmonare allergica (ABPA). Questa associazione pone tuttavia la possibilità di un rischio futuro di queste potenzialmente gravi manifestazioni allergiche respiratorie.</p>

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