scholarly journals Giant Cell Tumor of the Capitate and Hamate: Case Report and of Literature Review

2020 ◽  
Vol 09 (05) ◽  
pp. 425-430
Author(s):  
V. Abdusamad ◽  
Vivek Singh ◽  
Rohit Jain ◽  
Divya Singh
Keyword(s):  
Literature Review ◽  
Giant Cell ◽  
Histopathological Examination ◽  
Case Reports ◽  
English Literature ◽  
Hand Function ◽  
Autologous Bone Graft ◽  
Carpal Bones ◽  
Carpal Bone ◽  
Giant Cell Tumors

Abstract Background In the hand, giant cell tumors (GCTs) of the bones account for 2 to 5% of all hand tumors; they are often seen in the metacarpals and phalanges, seldom in the carpal bones. In the carpal bones, GCT usually occurs as a single lesion, with multifocal involvement being extremely rare. On analysis of recent English literature, we could find out only two reports having simultaneous involvement of multiple carpal bones. Case Description We report a case of a 29-year-old female with simultaneous involvement of two carpal bones: capitate and hamate. After confirming the diagnosis by histopathological examination, the affected carpals were resected, and the defect was filled with autologous bone graft. Follow-up at 18 months demonstrated no evidence of local recurrence or metastatic disease, and the patient is now having a reasonable hand function. Literature Review We analyzed nine case reports on GCTs in carpal bones in the past 25 years. Seven out of nine cases that we could analyze showed single carpal bone involvement (three capitate, two scaphoid, one hamate, one triquetrum). In these, four patients had undergone resection, and five patients had undergone curettage, of whom one patient came back 5 months later with recurrence. Only two cases were there with simultaneous involvement of multiple carpal bones. Both the cases were managed with resection and reconstruction with autologous graft iliac graft. Clinical Relevance GCTs of the carpal bones are relatively rare, and simultaneous involvement of two bones is rarer. Every attempt should be made to preserve useful wrist range of motion by excision and limited carpal fusion.

Giant Cell Tumor of Triquetrum: A Case Report with Literature Review

2020 ◽  
Author(s):  
Mohammed T. Ansari ◽  
Vijay K. Digge ◽  
Asjad Mahmood
Keyword(s):  
Literature Review ◽  
Giant Cell Tumor ◽  
Giant Cell ◽  
Case Reports ◽  
Cell Tumor ◽  
Carpal Bone ◽  
Scaphoid Bone ◽  
Intralesional Curettage ◽  
High Tendency ◽  
Long Term Study

Abstract Background Giant cell tumor (GCT) of bone is a benign, aggressive tumor of bone and occurs commonly around the knee and distal radius. GCT of bone rarely occurs in hand. In hand, metacarpals are the most common site and there have been only a few case reports of GCT of the carpal bone. In hand, these tumors are very aggressive and these have a high tendency to recur after intralesional curettage. No long-term study is available for choosing an appropriate method of treatment for these tumors in hand. Case Description Herein, we report a case of GCT of the bone involving triquetrum which was managed by excision of triquetrum and scaphoid bone. The reconstruction of the wrist was done through limited carpal fusion, by doing three corner fusion of the wrist. At 2 years after surgery, the patient was asymptomatic and radiographs revealed fusion of lunocapitate and lunohamate joints with no evidence of recurrence. Literature review Current literature regarding GCT of triquetrum includes case reports that are reviewed in this report. Clinical Relevance This case illustrates the successful treatment of GCT of triquetrum, which is a rare tumor. Three-corner fusion is a reliable and reproducible procedure that has been used for other arthritic conditions. The use of three corner fusion procedure can be extended to GCT of carpal bones. It has been a motion-preserving alternative to proximal row carpectomy (PRC).

Acute Herpetic Nasopharyngitis in an Adult Patient: A Case Report and Literature Review

2022 ◽  
pp. 000348942110701
Author(s):  
Cathleen C. Kuo ◽  
Ellen M. Piccillo ◽  
Jason C. DeGiovanni ◽  
Matt Kabalan ◽  
Gregg Zimmer ◽  
...  
Keyword(s):  
Literature Review ◽  
Adult Patient ◽  
Soft Palate ◽  
Case Reports ◽  
Nasal Congestion ◽  
English Literature ◽  
Immunohistochemical Analysis ◽  
Anatomical Location ◽  
Posterior Aspect ◽  
Mesh Terms

Objective: To report a case of herpes virus-associated nasopharyngitis in an adult patient. Methods: The patient’s medical record was reviewed for demographic and clinical data. For literature review, all case reports or other publications published in English literature were identified using Pubmed with the MeSH terms “herpes,” “nasopharyngitis,” and “upper respiratory infection.” Results: A 40-year-old male presented for nasal congestion and a suspected nasal mass. Computed tomography of the sinuses revealed edematous changes in the nasopharynx which exerted a downward mass effect at the right aspect of the soft palate. Flexible fiberoptic laryngoscopy (FFL) revealed a lesion arising from the posterior aspect of the soft palate with extension into the posterior nasal cavity as well as copious mucopurulent secretions consistent with a superimposed acute sinusitis. Rigid nasal endoscopy demonstrated a friable and ulcerated lesion arising from the aforementioned anatomical location. Biopsy of this lesion and subsequent immunohistochemical analysis revealed a diagnosis of herpetic nasopharyngitis. Conclusions: Herpetic infection should be in the differential diagnosis of patients presenting with atypical symptoms of nasopharyngitis. Early accurate diagnosis and appropriate specific management can limit the duration of disease course and prevent further complications.

scholarly journals Coronavirus disease 2019 infection and pituitary apoplexy: A causal relation or just a coincidence? A case report and review of the literature

2021 ◽  
Vol 12 ◽  
pp. 317
Author(s):  
Walaa A. Kamel ◽  
Mustafa Najibullah ◽  
Mamdouh S. Saleh ◽  
Waleed A. Azab
Keyword(s):  
Mr Imaging ◽  
Causal Relation ◽  
Histopathological Examination ◽  
Case Reports ◽  
English Literature ◽  
Clinical Findings ◽  
Oculomotor Nerve Palsy ◽  
Future Research ◽  
Endoscopic Endonasal ◽  
Transsphenoidal Resection

Background: Pituitary tumor apoplexy (PA) is an emergency condition caused by hemorrhage or infarction of the preexisting adenoma. Many factors are currently well-known to predispose to PA. However, during the period of coronavirus disease 2019 (COVID-19) pandemic, case reports of PA associated with COVID-19 infection have been sequentially published. To the best of our knowledge, four cases have been reported so far in the English literature. We herein report the fifth case of this association and review the pertinent literature. Case Description: A 55-year-old male patient with confirmed COVID-19 infection presented by progressive decrease in visual acuity and oculomotor nerve palsy. His medical history is notable for diabetes mellitus, hypertension, and pituitary macroadenoma resection 11 years ago. He was on hormonal replacement therapy for panhypopituitarism that complicated the surgery. Previous magnetic resonance (MR) imaging studies were consistent with enlarging residual pituitary adenoma. During the current hospitalization, computed tomography revealed hyperdensity of the sellar and suprasellar areas. MR imaging revealed PA in a recurrent large adenoma. Endoscopic endonasal transsphenoidal resection was uneventfully undertaken with near total excision of the adenoma and partial improvement of visual loss and oculomotor palsy. Histopathological examination demonstrated classic features of PA. However, his chest condition progressed and he had to be transferred to COVID-19 intensive care unit in the referring hospital where he was intubated and put on mechanical ventilation. One week later, the patient unfortunately passed away due to complications of severe COVID-19 pneumonia. Conclusion: We report the fifth case of PA associated with COVID-19 infection. Based on our patient’s clinical findings, review of the other reported cases, as well as the available literature, we put forth a multitude of pathophysiological mechanisms induced by COVID-19 that can possibly lead to the development of PA. In our opinion, the association between both conditions is not just a mere coincidence. Although the histopathological features of PA associated with COVID-19 are similar to PA induced by other etiologies, future research may disclose unique pathological fingerprints of COVID-19 virus that explains its capability of inducing PA.

Spindle Cell Lipomas of the Respiratory Tract: A Case Report and Comprehensive Literature Review

2019 ◽  
Vol 128 (11) ◽  
pp. 1086-1091 ◽  
Author(s):  
Jonathan Reid ◽  
Bret Wehrli ◽  
Leigh J. Sowerby
Keyword(s):  
Literature Review ◽  
Oral Cavity ◽  
Respiratory Tract ◽  
Spindle Cell ◽  
Case Reports ◽  
English Literature ◽  
Good Prognosis ◽  
Benign Tumors ◽  
Common Location ◽  
Literature Reviews

Background: Spindle cell lipomas (SCLs) are benign tumors that are characteristically present on the upper back and neck, but in rare cases present throughout the respiratory mucosa, causing hoarseness, stridor, dyspnea, and obstruction. Objective: To highlight the importance of considering SCL in the diagnosis of benign respiratory tract tumors, a literature review identified all published cases of respiratory tract SCLs, including 2 from our institution: one case in the nasopharynx and 1 in the nasal valve. Methods: All case reports, series and literature reviews from the English literature from 1975 through March 2018 were systematically identified for review in the MEDLINE, EMBASE, and Scopus databases. Two additional cases from our institution were described. Results: In total, 24 cases of SCL in the respiratory tract were identified for review. Two cases from our institution are described here, bringing the total of reported cases to 26. Extensive analyses of oral cavity SCLs already exist, so we excluded this site from our review and focused on sites where SCLs may present with respiratory symptoms. Excluding the oral cavity and oropharynx, the most common location described is the larynx. All 26 cases were treated with excision. One tumor required a second surgery, but there were no other complications nor recurrences. Conclusion: Although rare, SCLs may arise from throughout the respiratory tract and cause dyspnea, hoarseness and stridor. Spindle cell lipoma should be considered in the differential diagnosis of a respiratory tract mass. This diagnosis confers a good prognosis and patients may be reassured that surgery is almost always curative.

scholarly journals SCROTAL CALCINOSIS - RARE CASE REPORTS OF TWO CASES

2012 ◽  
Vol 02 (02) ◽  
pp. 57-59
Author(s):  
Harish S. Permi ◽  
Rohan Shetty ◽  
Shalmali Alva ◽  
Balakrishna Shetty ◽  
Rajesh Ballal ◽  
...  
Keyword(s):  
Giant Cell ◽  
Rare Case ◽  
Histopathological Examination ◽  
Case Reports ◽  
Amorphous Material ◽  
Benign Disease ◽  
Cell Reaction ◽  
Granulomatous Reaction ◽  
Large Size

AbstractScrotal calcinosis is a benign disease characterized by multiple calcified scrotal nodules. The nodules develop slowly over many years and patients usually do not seek for treatment, until they grow to large size. Histopathological examination shows deposition of basophilic amorphous material surrounded by giant cell granulomatous reaction. We report two cases of scrotal calcinosis occurring in 27 year and 45 year old males who presented with multiple scrotal swellings. Clinical diagnosis was multiple sebaceous cysts. On histopathology, excised swellings showed deposition of calcium with giant cell reaction. On regular follow up both are doing fine without any recurrence.

scholarly journals Tenosynovial giant cell tumors as accidental findings after episodes of distortion of the ankle: two case reports

2009 ◽  
Vol 3 (1) ◽  
Author(s):  
Christian Illian ◽  
Horst-Rainer Kortmann ◽  
Hans Otto Künstler ◽  
Ludger W Poll ◽  
Markus Schofer
Keyword(s):  
Giant Cell ◽  
Case Reports ◽  
Giant Cell Tumors

scholarly journals Acute haemoperitoneum caused by endometriosis infiltrating the uterine artery - Two case reports and a literature review

2021 ◽  
Vol 13 (3) ◽  
pp. 265-270
Author(s):  
A.-S. Vandenameele ◽  
L Platteeuw ◽  
H Alaerts
Keyword(s):  
Literature Review ◽  
Uterine Artery ◽  
Histopathological Examination ◽  
Case Reports ◽  
Free Fluid ◽  
Bipolar Coagulation ◽  
Lower Quadrant ◽  
Arterial Bleeding ◽  
The Right ◽  
Infiltrating Endometriosis

Objective: We report 2 cases of haemoperitoneum due to a bleeding of the uterine artery caused by infiltrating endometriosis. We have also conducted a literature review on endometriosis-related intra-abdominal haemorrhage and wrote a practical guideline on how this entity can be recognized and handled. Patients: Case 1: A 49-year-old multiparous woman presented with intense stabbing pain in the lower abdomen during her menstruation. CT angiography showed a bleeding from a side branch of the internal iliac artery. Laparoscopy was performed and an active bleeding from the right uterine artery was confirmed, clearly caused by infiltrating endometriosis lesions. Haemostasis was achieved by bipolar coagulation. Case 2: A 29-year-old nulliparous woman was admitted for observation because of heavy stabbing pain in the right lower quadrant and presence of free fluid on CT abdomen. The day after the admission, laparoscopy was performed because of a decreasing haemoglobin level. An arterial bleeding from the right parametrium was observed, probably originating from the right uterine artery. Histopathological examination of a biopsy of the right parametrium proved the presence of endometriosis. Haemostasis was achieved by bipolar coagulation. Conclusion: Although endometriosis-related haemoperitoneum is a rare entity, this diagnosis should be considered when a patient presents with an intra-abdominal haemorrhage during menstruation or withdrawal bleeding - especially in case of a history or suspicion of endometriosis. Laparoscopy is the cornerstone of the treatment.

Hemifacial Spasm as a Rare Clinical Presentation of Idiopathic Intracranial Hypertension: Case Report and Literature Review

2020 ◽  
Vol 129 (8) ◽  
pp. 829-832 ◽  
Author(s):  
Charles B. Poff ◽  
Noga Lipschitz ◽  
Gavriel D. Kohlberg ◽  
Joseph T. Breen ◽  
Ravi N. Samy
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Intracranial Hypertension ◽  
Hemifacial Spasm ◽  
Idiopathic Intracranial Hypertension ◽  
Case Reports ◽  
English Literature ◽  
Anterior Inferior Cerebellar Artery ◽  
First Report ◽  
History Of

Objectives: To report a rare case of idiopathic intracranial hypertension (IIH) presenting with hemifacial spasm (HFS) and review the current literature. Methods: Case report and literature review. The patient’s medical record was reviewed for demographic and clinical data. For literature review, all case reports or other publications published in English literature were identified using PUBMED. Results: A 43-year-old obese female presented with a 2-year history of left HFS. Electroencephalography and head computed tomography were unremarkable. Magnetic resonance imaging demonstrated bilateral anterior inferior cerebellar artery vascular loops involving the internal auditory canals as well as IIH-associated findings. A lumbar puncture was performed and revealed an elevated opening pressure of 26 cm H20 cerebrospinal fluid. Acetazolamide treatment was then initiated, resulting in complete resolution of the HFS. Conclusion: HFS may be a rare presenting manifestation of IIH, and treatment of IIH may result in improvement of HFS symptoms. This is the first report of IIH presenting with HFS in the absence of headache or visual change. As a result, this is the first report of HFS as a presenting manifestation of IIH in Otolaryngology literature.

GIANT CELL TUMORS IN CARPAL BONES

Orthopedics ◽  
1994 ◽  
Vol 17 (2) ◽  
pp. 181-185
Author(s):  
Charles S Lane ◽  
Stuart H Kuschner ◽  
Joseph M Mirra
Keyword(s):  
Giant Cell ◽  
Carpal Bones ◽  
Giant Cell Tumors

scholarly journals Aggressive osteoblastoma with a secondary aneurysmal bone cyst treated with denosumab

Rare Tumors ◽  
2021 ◽  
Vol 13 ◽  
pp. 203636132110347
Author(s):  
Karlton Wong ◽  
Jomjit Chantharasamee ◽  
Scott Nelson ◽  
Mark A Eckardt ◽  
Kambiz Motamedi ◽  
...  
Keyword(s):  
Giant Cell ◽  
Case Reports ◽  
Bone Cyst ◽  
Young Patients ◽  
Axial Skeleton ◽  
Giant Cell Tumors ◽  
Bony Lesions ◽  
Aneurysmal Bone Cysts ◽  
Secondary Aneurysmal Bone Cyst ◽  
Primary Bone

Osteoblastomas and aneurysmal bone cysts (ABC) are rare benign bone tumors that make up about 1%–2% of primary bone malignancies, typically occurring in young patients with a median age of 20 years, most commonly effecting the axial skeleton. ABCs may develop independently as primary lesions, or secondary to other bony lesions including osteoblastomas, chondroblastomas, and giant cell tumors. Treatment of unresectable or extensive osteoblastomas can be challenging. In 2013, the Food and Drug Administration (FDA) approved denosumab for the treatment of giant cell tumors of the bone due to its efficacy in these morbid bony lesions. Various case reports have shown that osteoblastomas can respond to denosumab. Furthermore, numerous ABC case reports have described the efficacy of denosumab in these situations. We herein describe a unique case of a young patient with an aggressive osteoblastoma and secondary ABCs who was successfully treated with denosumab.

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