scholarly journals Retrograde Approach for Intra-arterial Chemotherapy Delivery in Retinoblastoma

Author(s):  
Giancarlo Saal-Zapata ◽  
Walter Durand ◽  
Alfredo Ramos ◽  
Raúl Cordero ◽  
Rodolfo Rodríguez

AbstractIntra-arterial chemotherapy (IAC) is currently, the first-line treatment for retinoblastomas with successful cure rates. In difficult access or unsuccessful catheterization of the ophthalmic artery (OA), the middle meningeal artery is a second alternative followed by the Japanese technique using balloon. Nevertheless, when a well-developed posterior communicating artery is present, a retrograde approach to the OA through this vessel can be performed to deliver the chemotherapeutic drugs.We present a case of an unsuccessful catheterization of the OA through the internal carotid artery due to a challenging configuration of the OA/carotid siphon angle and describe an alternative form of navigation and catheterization through the posterior circulation.To our knowledge, this is the third report of a successful retrograde catheterization of the OA for IAC and constitutes an alternative route to deliver chemotherapy.

2021 ◽  
pp. 197140092110246
Author(s):  
Giancarlo Saal-Zapata ◽  
Rodolfo Rodríguez ◽  
Aaron Rodriguez-Calienes ◽  
Raúl Cordero

Retinoblastoma is the most frequent ocular malignancy in the pediatric population and intra-arterial chemotherapy has emerged as the first-line treatment of this entity with cure rates ranging from 33–100%, depending on the severity of the disease. We present the case of an advanced retinoblastoma in a pediatric patient who underwent intra-arterial chemotherapy through a contralateral route due to unsuccessful catheterization of the ophthalmic artery. The patient was diagnosed with a class D retinoblastoma which underwent the catheterization of the ophthalmic artery through the contralateral internal carotid and through the anterior communicating artery. In this case, intra-arterial chemotherapy administration was successfully delivered without complications. Contralateral routes for intra-arterial chemotherapy are safe and allow adequate penetration of the chemotherapeutic drugs in cases where a well-developed anterior communicating artery is present.


1985 ◽  
Vol 93 (3) ◽  
pp. 298-312 ◽  
Author(s):  
Mitchell Marion ◽  
Raúl Hinojosa ◽  
Anwar A. Khan

Persistence of the stapedial artery is a rare event. Fewer than 30 cases have been reported since the discovery of this artery in 1836. We carried out a histopathologic study on three temporal bones from two patients who had this anomaly, and were able to trace the full course of the artery. In two specimens a large stapedial artery persisted and substituted for the middle meningeal artery. In the third, a small, persistent stapedial artery ended in the arterial plexus surrounding the facial nerve. Persistence is discussed in terms of embryogenesis, developmental theories, histologic findings, and clinical significance. The material suggests that the stapedial artery can persist to varying degrees


Skull Base ◽  
2004 ◽  
Vol 14 (3) ◽  
pp. 153-156 ◽  
Author(s):  
Mehmet Erkan Üstün ◽  
Mustafa Büyükmumcu ◽  
Muzaffer Şeker ◽  
Ahmet Kağan Karabulut ◽  
İsmihan İlknur Uysal ◽  
...  

Author(s):  
Kiana Moussavi ◽  
Mohammad Moussavi

Introduction : Embolization of the Middle Meningeal Artery (MMA) is a minimally invasive procedure used as an alternative or adjunctive treatment of chronic subdural hematoma (cSDH). The benefits of MMA embolization have been attributed to targeting of the pathophysiology of cSDH which currently favors a process of increasing inflammatory response causing immature and leaky neovascularization. The major dural arteries and hazards associated with their embolization have been thoroughly described in past literature. The unintended embolization of orbital arteries leading to blindness is the most significant hazard associated with MMA embolization. The purpose of this study is to present 5 cases demonstrating the success of our technique in the treatment of cSDH while preventing the possibility of blindness by coiling the anastomotic vessel between MMA and Ophthalmic Artery (OA) branches prior to particle embolization. Methods : After doing an Internal Carotid Artery (ICA) run and ensuring the origination of the OA from the ICA and observing retinal blush, we routinely infused 10–20mcg of Nitroglycerine into the main trunk of MMA through a microcatheter to dilate and better visualize the MMA branches including anastomosis. If the meningeo‐ophthalmic collaterals were visualized during the follow‐up microcatheter run, we coil embolized the proximal segment of those collaterals through the same microcatheter. We then infused 100–300µm particles through the main branches of the MMA supplying the dura. Results : Of the 39 patients who underwent MMA embolization for cSDH, 5 received MMA/OA collateral variants coil embolization followed by successful particle embolization of all MMA branches supplying the dura without complication. Conclusions : In our cSDH patients, the collaterals from MMA to Ophthalmic or Lacrimal branches were safely coil embolized before complete particle embolization of the MMA dural branches. In a few patients these collaterals became obvious after inducing vasodilatation. None of these patients had major complications. This technique may be safer, more effective and cheaper than wedging, gluing or low pressure infusion. Our literature search did not find a similar technique used in this application.


2006 ◽  
Vol 188 (1) ◽  
pp. 33-38 ◽  
Author(s):  
Katsushi Kawai ◽  
Kazuya Yoshinaga ◽  
Masahiro Koizumi ◽  
Satoru Honma ◽  
Akinari Tokiyoshi ◽  
...  

2021 ◽  
Author(s):  
MirHojjat Khorasanizadeh ◽  
Mira Salih ◽  
Dominic Harris ◽  
Christopher S Ogilvy

Abstract Transvenous embolization is the favored treatment for indirect carotid-cavernous fistulas (CCFs). However, transarterial embolization can be used as an alternative method when the venous route is inaccessible. We present the case of a 47-yr-old woman with a history of diplopia, headaches, and sixth cranial nerve (CN-VI) palsy who presented with acute worsening of headache and ophthalmoplegia and rise of intraocular pressures. Angiography demonstrated a left indirect CCF (dural arteriovenous malformation) with multiple arterial feeders from the internal carotid artery as well as the middle meningeal artery (MMA) (Barrow type D). Transvenous approach was attempted first but was unsuccessful due to difficult access to the cavernous sinus. Thus, transarterial embolization through the MMA feeding branches was planned. To avoid occluding distal branches of the MMA by Onyx, we coiled it distally. In addition, we used a scepter balloon proximally to prevent the reflux of Onyx into potential collaterals to cranial nerves from proximal MMA. After trapping a segment of the MMA, Onyx was injected into the CCF fistula through the small MMA feeders. A postembolization arteriogram showed obliteration of the CCF. The patient developed mild left facial nerve paresis on the first postoperative day (thought to be related to partial embolization of tiny arteries in the facial canal), which was resolving in the course of hospitalization. She remained neurologically stable, and was discharged on the third postoperative day. To the best of our knowledge, this is the first report of transarterial embolization of CCF by distal coiling and proximal ballooning to trap a segment of an artery. The authors hereby confirm that informed consent was obtained from the patient after thorough discussion of the procedure's rationale, risks, benefits, and alternatives.


2019 ◽  
Vol 26 (1) ◽  
pp. 111-117
Author(s):  
M AlMatter ◽  
M Aguilar Pérez ◽  
V Hellstern ◽  
U Quäschling ◽  
O Ganslandt ◽  
...  

Deviations from normal embryologic development can manifest in different anatomical variants of the ophthalmic artery. We present a case of an infant treated for a high-flow dural arteriovenous fistula of the superior sagittal sinus, in whom an arterial circle involving the ophthalmic artery, the middle meningeal artery, the inferolateral trunk and a hypoplastic segment of the internal carotid artery was found. The embryologic development is briefly reviewed with emphasis on the possible genesis of this interesting constellation.


1971 ◽  
Vol 34 (6) ◽  
pp. 823-826 ◽  
Author(s):  
Naim K. Atallah ◽  
Sami I. Nassar

✓ The sources of blood supply of calvarial hemangiomas are not well established angiographically but have been reported to derive from the middle meningeal artery. A case is presented in which both the external and the internal carotid arteries supplied the hemangioma. The protean arteriographic picture is explained in terms of the various tissues the tumor involves (galea, calvarium, or meninges).


2013 ◽  
Vol 02 (02) ◽  
pp. 196-198
Author(s):  
Qinghai Huang ◽  
Jianmin Liu ◽  
Xinpu Chen

Abstract Maxillofacial arteriovenous malformation (AVM) is a rare, but potentially life-threatening entity. Surgical excision usually associates with a high rate of significant blood loss and cosmetic defects. We report a patient who had an AVM involving infratemporal fossa and parotid region, supplied by an enlarged branch of the left ophthalmic artery, cavernous internal carotid artery, middle meningeal artery, and internal maxillary. Successful treatment of this lesion was achieved by transarterial embolization with Onyx. Less invasive transarterial embolization with Onyx is rewarding when curing certain types of maxillofacial AVMs.


2020 ◽  
Vol 26 (3) ◽  
pp. 354-357
Author(s):  
Ajit Mishra ◽  
Subhas K Konar ◽  
Dhananjaya I Bhat ◽  
S Nishant ◽  
B Indira Devi

Ophthalmic artery (OA) is known for anomalous origin and aberrant course probably attributable to its complex embryology. Anomalous origin of OA can be associated with intracranial aneurysm. Anomalous origins have been reported from middle meningeal artery (MMA), cavernous carotid, posterior communicating, anterior cerebral and basilar artery. Even though bilateral anomalous origin of OA from MMA is a rare finding, to the author’s best knowledge, association of above condition with bilateral internal carotid artery aneurysms has not been described in the literature. We present a case of such anomalous bilateral OA originating from MMA and associated with bilateral internal carotid artery aneurysms. We have also reviewed the pertinent literature regarding anomalous OA origin.


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